Allosteric, chiral-selective drug binding to DNA

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 22, 2000, Pages 12032-12037

  Qu, Xiaogang ^a   Trent, John O ^b   Fokt, Izabela ^c   Priebe, Waldemar ^c   Chaires, Jonathan B ^a  

^a UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

^b University of Louisville School of Medicine   (United States)

^c UNIVERSITY OF TEXAS   (United States)

Author keywords

Allostery; Drug design; Molecular dynamics; Molecular recognition

Indexed keywords

ANTINEOPLASTIC AGENT; DAUNORUBICIN; DNA; WP 900;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; CHIRALITY; CIRCULAR DICHROISM; CONTROLLED STUDY; DNA CONFORMATION; DRUG DNA BINDING; ENANTIOMER; EQUILIBRIUM DIALYSIS; FLUORESCENCE SPECTROSCOPY; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; PRIORITY JOURNAL; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; NUCLEOTIDE SEQUENCE; STEREOISOMERISM;

ALLOSTERIC REGULATION; BASE SEQUENCE; DAUNORUBICIN; DNA; MODELS, MOLECULAR; STEREOISOMERISM;

EID: 0034710853     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.200221397     Document Type: Article

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