Thyroid hormone stimulation of osteocalcin gene expression in ROS 17/2.8 cells is mediated by transcriptional and post-transcriptional mechanisms

Journal of Endocrinology

Volumn 170, Issue 3, 2001, Pages 667-675

  Gouveia, C H ^a   Schultz, J J ^a   Bianco, A C ^a   Brent, G A ^a  

^a VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; CALCITRIOL; CYCLOHEXIMIDE; DACTINOMYCIN; DNA; LIOTHYRONINE; MESSENGER RNA; OSTEOCALCIN; OSTEOPONTIN; THYROID HORMONE; VITAMIN D;

ANIMAL CELL; ARTICLE; ASSAY; BONE DEVELOPMENT; CANCER CELL CULTURE; CELL DENSITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; GENE CONSTRUCT; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HALF LIFE TIME; HORMONAL REGULATION; INCUBATION TIME; NONHUMAN; OSTEOBLAST; OSTEOSARCOMA; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN SYNTHESIS; RAT; REPORTER GENE; TIME;

ANIMALS; BONE NEOPLASMS; GENE EXPRESSION REGULATION; OSTEOBLASTS; OSTEOCALCIN; OSTEOSARCOMA; RATS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TRIIODOTHYRONINE; TUMOR CELLS, CULTURED;

EID: 0034824203     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1700667     Document Type: Article

References (50)

1. Thyroid hormones and bone
2. The isoform-specific expression of the triiodothyronine receptor in osteoblasts and osteoclasts
3. Factors that promote progressive development of the osteoblast phenotype in cultured fetal rat calvaria cells
4. Hormonal regulation of lipogenic enzymes in chick embryo hepatocytes in culture. Thyroid hormone and glucagon regulate malic enzyme mRNA level at post-transcriptional steps
5. 3 analog KH1060
6. Triiodothyronine amplifies norepinephrine stimulation of uncoupling protein gene transcription by a mechanism not requiring protein synthesis
7. Fourier transform infrared microspectroscopic analysis of bones of osteocalcin-deficient mice provides insight into the function of osteocalcin
8. Characterization of a negative thyroid hormone response element in the rat sodium, potassium-adenosine triphosphatase alpha3 gene promoter
9. Hormone binding induces rapid proteasome-mediated degradation of thyroid hormone receptors
10. 3 on gene transcription
11. A therapeutic dilemma: Suppressive doses of thyroxine significantly reduce bone mineral measurements in both premenopausal and postmenopausal women with thyroid carcinoma
12. Increased bone formation in osteocalcin-deficient mice
13. Concerted control of multiple histone promoter factors during cell density inhibition of proliferation in osteosarcoma cells: Reciprocal regulation of cell cycle-controlled and bone-related genes
14. The T3R alpha gene encoding a thyroid hormone receptor is essential for post-natal development and thyroid hormone production
15. Different functions for the thyroid hormone receptors TRalpha and TRbeta in the control of thyroid hormone production and post-natal development
16. Impaired recruitment and differentiation of osteoclast progenitors by osteocalcin-deplete bone implants
17. Mice devoid of all known thyroid hormone receptors are viable but exhibit disorders of the pituitary-thyroid axis, growth, and bone maturation
18. Effects of thyroid hormone administration and estrogen deficiency on bone mass of female rats
19. Triiodothyronine regulates beta 3-adrenoceptor expression in 3T3-F442A differentiating adipocytes
20. Serum concentrations of osteocalcin in patients with hyperthyroidism, hypothyroidism and subacute thyroiditis
21. Spinal bone mineral content in myxoedema and thyrotoxicosis. Effects of thyroid hormone(s) and antithyroid treatment
22. A rat model of thyroid hormone-induced bone loss: Effect of antiresorptive agents on regional bone density and osteocalcin gene expression
23. Thyroid hormone 5′-deiodinase activity, nuclear binding, and effects on mitogenesis in UMR-106 osteoblastic osteosarcoma cells
24. Bone mineral density and metabolism in children with congenital hypothyroidism after prolonged L-thyroxine therapy
25. 1,25-Dihydroxyvitamin D3 stimulates rat osteoblastic cells to release a soluble factor that increases osteoclastic bone resorption
26. 3 metabolism in normal and type 1 deiodinase-deficient mice
27. 3
28. A tetracycline-based histomorphometric evaluation of bone resorption and bone turnover in hyperthyroidism and hyperparathyroidism
29. The propeptide of rat bone gamma-carboxyglutamic acid protein shares homology with other vitamin K-dependent protein precursors
30. Regulation of rabbit cytochrome P450 2E1 expression in HepG2 cells by insulin and thyroid hormone
31. Triiodothyronine induces collagenase-3 and gelatinase B expression in murine osteoblasts
32. Regulation of thyroid hormone nuclear receptor levels in GH1 cells by 3,5,3′-triido-L-thyronine. Use of dense amino acid labeling to determine the influence of hormone on the receptor half-life and the rate synthesized receptor
33. Thyroid hormone receptor does not heterodimerize with the vitamin D receptor but represses vitamin D receptor-mediated transactivation
34. Transcriptional and posttranscriptional mechanisms in uncoupling protein mRNA response to cold
35. Nuclear thyroid hormone receptors in cultured bone cells
36. Increased rat femur osteocalcin mRNA concentrations following in vivo administration of thyroid hormone
37. Thyroid hormone stimulates alkaline phosphatase activity in cultured rat osteoblastic cells (ROS 17/2.8) through 3,5,3′-triiodo-L-thyronine nuclear receptors
38. 3-thyroid hormone receptor heterodimer polarity directs ligand sensitivity of transactivation
39. Specificity and flexibility of vitamin D signaling. Modulation of the activation of natural vitamin D response elements by thyroid hormone
40. Multiple levels of steroid hormone-dependent control of osteocalcin during osteoblast differentiation: Glucocorticoid regulation of basal and vitamin D stimulated gene expression
41. DNA sequences downstream from the vitamin D response element of the rat osteocalcin gene are required for ligand-dependent transactivation
42. Transcriptional control of osteoblast growth and differentiation
43. Differential regulation of the expression of fast-type sarcoplasmic-reticulum Ca(2+)-ATPase by thyroid hormone and insulin-like growth factor-I in the L6 muscle cell line
44. Msx-2/Hox 8.1: A transcriptional regulator of the rat osteocalcin promoter
45. Thyroid hormone modulates apolipoprotein-AI gene expression at the post-transcriptional level in Hep G2 cells
46. 3, and retinoid signaling
47. 3 and thyroid hormone in three osteosarcoma cell lines
48. Vitamin D receptors repress basal transcription and exert dominant negative activity on triiodothyronine-mediated transcriptional activity
49. Influence of thyroid function on serum bone Gla protein