Effects of thyroid hormone administration and estrogen deficiency on bone mass of female rats

Journal of Bone and Mineral Research

Volumn 12, Issue 12, 1997, Pages 2098-2107

  Gouveia, Cecilia H A ^a   Jorgetti, Vanda ^a   Bianco, Antonio C ^a,b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b Office #140   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

THYROXINE;

ANIMAL MODEL; ARTICLE; BONE MASS; CONTROLLED STUDY; CORTICAL BONE; ESTROGEN DEFICIENCY; FEMALE; HORMONE ACTION; INTRAPERITONEAL DRUG ADMINISTRATION; NONHUMAN; OSTEOPENIA; OVARIECTOMY; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; TRABECULAR BONE;

EID: 0030731805     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.1997.12.12.2098     Document Type: Article

References (60)

1. Mundy GR, Shapiro JL, Bandelin JG, Canalis EM, Raisz LG 1976 Direct stimulation of bone resorption by thyroid hormones. J Clin Invest 58:529-534.
2. Britto JM, Fenton AJ, Holloway WR, Nicholson GC 1994 Osteoblasts mediate thyroid hormone stimulation of osteoclastic bone resorption. Endocrinology 134:169-176.
3. Rizzoli R, Poser J, Bürgi U 1986 Nuclear thyroid hormone receptors in cultured bone cell. Metabolism 35:71-74.
4. Wilkings JN, Mayer SE, Vanderlaan WP 1974 The effects of hypothyroidism and 2,4-dinitrophenol on growth hormone synthesis. Endocrinology 95:1259.
5. Evans RM, Birnberg NC, Rosenfeld MG 1982 Glucocorticoid and thyroid hormones transcriptionally regulate growth hormone gene expression. Proc Natl Acad Sci USA 79:7659.
6. 1 on thyroid hormone action in cultured fetal rat limb bones. Calcif Tissue Int 50:123-128.
7. Rasmussen H, Bordier P 1974 The Physiological and Cellular Basis of Metabolic Bone Disease. Williams & Wilkins, Baltimore, MD, U.S.A., pp. 194-196.
8. Mosekilde L, Melsen F 1978 Morphometric and dynamic studies of bone changes in hypothyroidism. Acta Path Microbiol Scand Sect A 86:56-62.
9. Kragstrup J, Melsen F, Mosekilde 1981 Effects of thyroid hormone(s) on mean wall thickness of trabecular bone packets. Metab Bone Dis Rel Res 3:181-185.
10. Melsen F, Mosekilde L 1977 Morphometric and dynamic studies of bone changes in hyperthyroidism. Acta Pathol Microbiol Scand [A] 85:141.
11. Coindre J, David J, Riviére L, Goussot J, Roger P, de Mascarel A, Meunier PJ 1986 Bone loss in hypothyroidism with hormone replacement: A histomorphometric study. Arch Intern Med 146:48-53.
12. Eriksen EF, Mosekilde L, Melsen F 1985 Trabecular bone remodeling and bone balance in hyperthyroidism. Bone 6:421-428.
13. Krane SM, Brownell GL, Stanbury JB, Corrigan H 1956 The effect of thyroid disease on calcium metabolism in man. J Clin Invest 35:874-887.
14. Tohn SH, Claunch BC, Brown PH 1985 Effect of hyperthyroidism and its treatment on bone mineral content. Arch Intern Med 145:883-886.
15. von Recklinghausen FC 1891 Die fibrose oder deformierende Ostitis, die Osteomalazie und die osteoplastische Karcinose in ihren gegenseitigen Beziehungen. In: Reimer G (ed.) Festschrif Rudol Virchou, Berlin, Germany, pp. 1-89.
16. Fraser SA, Anderson JB, Smith DA, Wilson GM 1971 Osteoporosis and fractures following thyrotoxicosis. Lancet 1:981-983.
17. Fallon MD, Perry HM III, Bergfeld M, Droke D, Teitelbaum SL, Avioli LV 1983 Exogenous hyperthyroidism with osteoporosis. Arch Intern Med 143:442-442.
18. Compston EJ 1993 Thyroid hormone therapy and the skeleton. Clin Endocrinol 39:519-520.
19. Burman KD 1995 How serious are the risks of thyroid hormone over-replacement? Thyroid Today 18:1-9.
20. Grant DJ, McMurdo MET, Mole PA, Paterson CR, Davies RR 1993 Suppressed TSH levels secondary to thyroxine replacement are not associated with osteoporosis. Clin Endocrinol 39:529-533.
21. Hawkins F, Rigopoulou D, Papapietro K, Lopez MB 1994 Spinal bone mass after long-term treatment with 1-thyroxine in postmenopausal women with thyroid cancer and chronic lymphocytic thyroiditis. Calcif Tissue Int 54:16-19.
22. Földes J, Tarján G, Szathmari M, Varga F, Krasznai I, Horvath Cs 1993 Bone mineral density in patients with endogenous subclinical hyperthyroidism: Is this thyroid status a risk factor for osteoporosis? Clin Endocrinol 39:521-527.
23. Uzzan B, Campos J, Cucherat M, Nony P, Boissel JP, Perret GY 1996 Effects on bone mass of long term treatment with thyroid hormones: A meta-analysis. J Clin Endocrinol Metab 81:4278-4289.
24. Diamond T, Nery L, Hales I 1991 A therapeutic dilemma: Suppressive doses of thyroxine significantly reduce bone mineral measurements in both premenopausal and post-menopausal women with thyroid carcinoma. J Clin Endocrinol Metab 72:1184-1188.
25. Rosen HN, Sullivan EK, Middlebrooks VL, Zeind AJ, Gundberg C, Pollak RD, Maitland LA, Hock JM, Moses AC, Greenspan SL 1993 Parenteral pamidronate prevents thyroid hormone-induced bone loss in rats. J Bone Miner Res 8:1255-1261.
26. Kung AW, Ng F 1994 A rat model of thyroid hormone-induced bone loss: Effect of antiresorptive agents on regional bone density and osteocalcin gene expression. Thyroid 4:93-98.
27. Allain TJ, Thomas MR, McGregor AM, Salisbury JR 1995 A histomorphometric study of bone changes in thyroid dysfunction in rats. Bone 16:505-509.
28. Dias AA Jr, Marone MMS, Lewin S, Corrêa PHS, Bianco AC 1990 Rapid bone mass recovery following medical treatment of hyperthyroidism: A comparison of lumbar spine and proximal femur by dual photon absorptiometry. The Endocrine Society 72nd Annual Meeting, Atlanta, GA, U.S.A., June, Abstract 323, p. 105.
29. Pastor MMC, Torres MM, Jimenez FE, Almodovar MR, Gimeno EJ 1993 Bone mass in females with different thyroid disorders: Influence of menopausal status. Bone Miner 21:1-8.
30. Bianco AC, Silva JE 1987 Intracellular conversion of thyroxine to triiodothyronine is required for the optimal thermogenic formation of brown adipose tissue. J Clin Invest 79:295-300.
31. Samuels HH, Stanley F, Casanova J 1979 Depletion of 1-3,5,3′-triiodothyronine and 1-thyroxine in euthyroid calf serum for use in cell culture studies of the action of thyroid hormone. Endocrinology 105:80-85.
32. Lu PW, Briody JN, Howman-Giles R, Trube A, Cowell CT 1994 DXA for bone density measurement in small rats weighing 150-250 g. Bone 15:199-202.
33. Fox KM, Kimura S, Plato CC, Kitagawa T 1995 Bilateral asymmetry in bone weight at various skeletal sites of the rat. Anatom Rec 241:284-287.
34. Schenk RK, Merz WA, Müller J 1969 A quantitative histological study on bone resorption in human cancellous bone. Acta Anat 74:44-53.
35. Gouveia CHA, Jorgetti V, Bianco AC 1995 Physiological doses of 1-thyroxine prevent the ovariectomy-induced bone loss in rats as measured by bone densitometry and histomorphometry. 17th Meeting of The American Society of Bone and Mineral Research September, Baltimore, MD, U.S.A. J Bone Miner Res 10 (Suppl 1): abstract T503.
36. Ongphiphadhanakul B, Alex S, Bravemann LE, Baran D 1992 Excessive 1-thyroxine therapy decreases femoral bone mineral densities in the male rat: effect of hypogonadism and calcitonin. J Bone Miner Res 7:1227-1231.
37. Suwanwalaikorn S, Ongphiphadanalkul B, Braverman LE, Baran DT 1996 Differential responses of femoral and vertebral bones to long-term excessive 1-thyroxine administration in adult rats. Eur J Endocrinol 134:655-659.
38. Rosen HN, Middlebrooks VL, Sullivan EK, Rosenblatt M, Maitland LA, Moses AC, Greenspan SL 1994 Subregion analysis of the rat femur: a sensitive indicator of changes in bone density following treatment with thyroid hormone or bisphosphonates. Calcif Tissue Int 55:173-175.
39. Paul TL, Kerrigan J, Kelly AM, Braverman LE, Baran DT 1988 Long-term 1-thyroxine therapy is associated with decreased hip bone density in premenopausal women. JAMA 259:3137-3141.
40. Lazar MA 1993 Thyroid hormone receptors: Multiple forms, multiple possibilities. Endocr Rev 14:184-193.
41. Baran DI 1994 Detrimental skeletal effects of thyrotropin suppressive doses of thyroxine: Fact or fantasy? J Clin Endocrinol Metab 78:816-817.
42. Oppenheimer JH, Schwartz HL, Lane JT, Thompson MP 1991 Functional relationship of thyroid hormone - induced lipogenesis, lipolysis, and thermogenesis in rat. J Clin Invest 87:125-132.
43. Kimmel DB, Thomas J, Wronski 1990 Nondestructive measurement of bone mineral in femurs from ovariectomized rats. Calcif Tissue Int 46:101-110.
44. Beall PT, Misra LK, Young RL, Spjut HJ, Evans HJ, LeBlanc A 1984 Clomiphene protects against osteoporosis in the mature ovariectomized rat. Calcif Tissue Int 36:123-125.
45. Samuels HH 1983 Identification and characterization of thyroid hormone receptors and action using cell culture techniques. In: Oppenheimer and Samuels (eds.) Molecular Basis of Thyroid Hormone Action, 1st Ed. Academic Press, New York, NY, U.S.A., pp. 36-65.
46. Wolf M, Ingbar SH, Moses AC 1989 Thyroid hormone and growth hormone interact to regulate insulin-like growth factor-I messenger ribonucleic acid and circulating levels in the rat. Endocrinology 125:2905-2914.
47. Spencer EM, Liu CC, Si ECC, Howard GA 1991 In vivo actions of insulin-like growth factor-I (IGF-I) on bone formation and resorption in rats. Bone 12:21-26.
48. Tobias JH, Chow JWM, Chambers TJ 1992 Opposite effects of insulin-like growth factor-I on the formation of trabecular and cortical bone in adult female rats. Endocrinology 131:2387-2392.
49. Andreassen TT, Jorgensen PH, Flyvbjerg A, Orskov H, Oxlund H 1995 Growth hormone stimulates bone formation and strength of cortical bone in aged rats. J Bone Miner Res 10:1057-1067.
50. Johansson AG, Lindh E, Blum WF, Kollerup G, Sorensen OH, Ljunghall S 1996 Effects of growth hormone and insulin-like growth factor-I in men with idiopathic osteoporosis. J Clin Endocrinol Metab 81:44-48.
51. Hunter WM, Greenwood FC 1964 Studies on the secretion of human-pituitary-growth hormone. Br Med J 5386:804.
52. Frantz AG, Rabkin MT 1965 Effects of estrogen and sex difference on secretion of human growth hormone. J Clin Endocrinol Metab 25:1470.
53. Schalch DS 1967 The influence of physical stress and exercise on growth hormone and insulin secretion in man. J Lab Lin Med 69:256.
54. Wiedemann E, Schwartz E, Frantz AG 1976 Acute and chronic estrogen effects upon serum somatomedin activity, growth hormone and prolactin in man. J Clin Endocrinol Metab 42:942.
55. Dawson-Hughes B, Stern D, Goldman J, Reichlin S 1986 Regulation of growth hormone and somatomedin-C secretion in postmenopausal women: Effect of physiological estrogen replacement. J Clin Endocrin ol Metab 63:424-432.
56. Simard J, Hubert J-F, Hosseinzadeth T, Labrie F 1986 Stimulation of growth hormone release and synthesis by estrogen in rat anterior pituitary in culture. Endocrinology 119:2004-2011.
57. 3H]-estradiol in GRF neurons. Endocrinology 127:344-349.
58. Dipippo VA, Lindsay R, Powers A 1995 Estradiol and tamoxifen interactions with thyroid hormone in the ovariectomized-thyroidectomized rat. Endocrinology 136:1020-1033.
59. Lewin S, Gouveia CHA, Marone MMS, Wehba S, Malvestiti LF, Bianco AC 1997 Vertebral and femoral bone mineral density of 724 normal Brazilian women. Rev Assoc Med Bras 43(2): 127-136.
60. Oppenheimer JH, Schwartz HL, Strait KA 1995 An integrated view of thyroid hormone actions in vivo. In: Weintraub BD (ed.) Molecular Endocrinology: Basic Concepts and Clinical Correlation. Raven Press, New York, NY, U.S.A., pp. 249-268.