Selective development of a strong Th2 cytokine profile in high-risk children who develop atopy: Risk factors and regulatory role of IFN-γ, IL-4 and IL-10

Clinical and Experimental Allergy

Volumn 31, Issue 7, 2001, Pages 997-1006

  Van Der Velden, V H J ^a   Laan, M P ^a   Baert, M R M ^a   De Waal Malefyt, R ^c   Neijens, H J ^b   Savelkoul, H F J ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Allergen; Atopy; Cord blood; Cytokines; High risk children; Risk factors; Th1 Th2

Indexed keywords

ALLERGEN; CD4 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5;

ANALYTIC METHOD; ARTICLE; ATOPIC DERMATITIS; ATOPY; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE RESPONSIVE ELEMENT; DATA ANALYSIS; DISEASE COURSE; DOWN REGULATION; GENETIC RISK; HIGH RISK POPULATION; HUMAN; IMMUNE RESPONSE; INFLAMMATION; MAJOR CLINICAL STUDY; MONONUCLEAR CELL; NEWBORN; PRIORITY JOURNAL; REGULATORY MECHANISM; RISK FACTOR; SMOKING HABIT; STIMULATION; TH2 CELL;

ALLERGENS; CLONE CELLS; CYTOKINES; FEMALE; FETAL BLOOD; HUMANS; HYPERSENSITIVITY, IMMEDIATE; INFANT; INFANT, NEWBORN; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; MALE; PHENOTYPE; RISK FACTORS; TH2 CELLS;

EID: 0034817716     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2222.2001.01176.x     Document Type: Article

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