Heat shock protein 90 and the nuclear transport of progesterone receptor

Cell Stress and Chaperones

Volumn 6, Issue 3, 2001, Pages 256-262

  Haverinen, Marjaana ^a   Passinen, Satu ^a   Syvälä, Heimo ^b   Pasanen, Susanna ^a   Manninen, Tommi ^a   Tuohimaa, Pentti ^b,c   Ylikomi, Timo ^a,c  

^a Graduate School of Biosciences   (Finland)

^b UNIVERSITY OF TAMPERE MEDICAL SCHOOL   (Finland)

^c TAMPERE UNIVERSITY HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; DIGITONIN; ESTRADIOL; HEAT SHOCK PROTEIN 90; NUCLEAR PROTEIN; OLIGOMER; PROGESTERONE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CHICKEN; CONTROLLED STUDY; CYTOSOL; DISSOCIATION; HELA CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MEMBRANE PERMEABILITY; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; OVIDUCT; PRIORITY JOURNAL; PROTEIN TRANSPORT; RETICULOCYTE LYSATE;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL NUCLEUS; CHICKENS; FEMALE; HELA CELLS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MACROMOLECULAR SUBSTANCES; OVIDUCTS; RECEPTORS, PROGESTERONE;

EID: 0034817258     PISSN: 13558145     EISSN: None     Source Type: Journal    
DOI: 10.1379/1466-1268(2001)006<0256:HSPATN>2.0.CO;2     Document Type: Article

References (56)

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6. The common 90-kd protein component of non-transformed '8S' steroid receptors is a heat-shock protein
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14. Nucleocytoplasmic shuttling of the progesterone receptor
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16. Molybdate inhibits Hsp90, induces structural changes in its C-terminal domain, and alters its interactions with substrates
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19. Heat shock protein 90 strongly stimulates the binding of purified estrogen receptor to its responsive element
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21. Characterization of a novel 23-kilodalton protein of unactive progesterone receptor complexes
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31. The cytoskeleton and the cellular traffic of the progesterone receptor
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35. Nuclear protein migration involves two steps: Rapid binding at the nuclear envelope followed by slower translocation through nuclear pores
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40. Animal and plant cell lysates share a conserved chaperone system that assembles the glucocorticoid receptor into a functional heterocomplex with Hsp90
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45. Nuclear progesterone receptor is mainly heat shock protein 90-free in vivo
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47. Translational regulation by steroids: Identification of a steroid modulatory element in the 5′-untranslated region of the myelin basic protein messenger RNA
48. Antibodies to chicken progesterone receptor peptide 523-536 recognize a site exposed in receptor-deoxyribonucleic acid complexes but not in receptor-heat shock protein-90 complexes
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53. Differential roles of heat shock protein 70 in the in vitro nuclear import of glucocorticoid receptor and simian virus 40 large tumor antigen
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