Tumor necrosis factor-α and nitric oxide in vertically HIV-1-infected children: Implications for pathogenesis

European Cytokine Network

Volumn 12, Issue 3, 2001, Pages 437-444

  Gonzalez Nicolas J ^a   Resino, S ^a   Jimenez J L ^a   Alvarez, S ^a   Fresno, M ^a   Munoz Fernandez M A ^a  

^a HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

Author keywords

HIV infection; Immunological and virological markers; Nitric oxide; Tumor necrosis factor

Indexed keywords

NITRIC OXIDE; NITRIC OXIDE SYNTHASE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HOST RESISTANCE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOPATHOGENESIS; IMMUNOREACTIVITY; MALE; VERTICAL TRANSMISSION; VIRUS TRANSMISSION;

CELLS, CULTURED; CHILD, PRESCHOOL; CROSS-SECTIONAL STUDIES; DISEASE TRANSMISSION, VERTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; FEMALE; HIV INFECTIONS; HIV-1; HUMANS; MALE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OMEGA-N-METHYLARGININE; TUMOR NECROSIS FACTOR-ALPHA; VIRAL LOAD; VIRUS REPLICATION;

EID: 0034816954     PISSN: 11485493     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Nitric oxide: A physiologic messenger molecule
2. Nitric oxide: What role does it play in inflammation and tissue destruction?
3. Nitric oxide in inflammation and immune response
4. Nitric oxide: Physiology, pathophysiology, and pharmacology
5. Regulation of lymphocyte functions by nitric oxide
6. Nitric oxide synthases: Roles, tolls, and controls
7. Role of nitric oxide in autoimmunity
8. Nitric oxide synthases in mammals
9. Nitric oxide and macrophage function
10. Nitric oxide regulates Th1 cell development through the inhibition of IL-12 synthesis by macrophages
11. Altered immune responses in mice lacking inducible nitric oxide synthase
12. The multiplex function of nitric oxide in (auto)immunity
13. Activation of human peripheral blood mononuclear cells by nitric oxide-generating compounds
14. Nitric oxide suppresses human T lymphocyte proliferation through IFN-gamma-dependent and IFN-gamma-independent induction of apoptosis
15. Macrophage-derived nitric oxide regulates T cell activation via reversible disruption of the Jak3/STAT5 signaling pathway
16. Nitric oxide synthase plays a signaling role in TCR-triggered apoptotic death
17. Nitric oxide regulates endotoxin-induced TNF-alpha production by human neutrophils
18. Cytokines in HIV infection
19. Increased spontaneous secretion of interleukin-6 and tumor necrosis factor alpha by peripheral blood lymphocytes of human immunodeficiency virus-infected children
20. Replication of human immunodeficiency virus-1 in primary human T cells is dependent on the autocrine secretion of tumor necrosis factor through the control of nuclear factor-kappa B activation
21. The effect of cytokines and pharmacologic agents on chronic HIV infection
22. Tumor necrosis factor alpha functions in an autocrine manner in the induction of human immunodeficiency virus expression
23. Elevated cerebrospinal fluid and serum nitrate and nitrite levels in patients with central nervous system complications of HIV-1 infection: A correlation with blood-brain-barrier dysfunction
24. Increased production of nitric oxide correlates with viral load and activation of mononuclear phagocytes in HIV-infected patients
25. Production of nitric oxide from peripheral blood mononuclear cells and polymorphonuclear leukocytes of patients with HIV-1
26. Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: Implications for HIV- associated neurological disease
27. A critical role of nitric oxide in human immunodeficiency virus type 1-induced hyperresponsiveness of cultured monocytes
28. Role of nitric oxide in the regulation of lymphocyte apoptosis and HIV-1 replication
29. HIV-1 infection induces differentiation of immature neural cells through autocrine tumor necrosis factor and nitric oxide production
30. Relationship of virologic, immunologic, and clinical parameters in infants with vertically acquired human immunodeficiency virus type 1 infection
31. Center for diseases control prevention. Revised classification system for HIV-1 infection in children less than 13 years of age
32. Elevated levels of circulating intercellular adhesion molecule 1 and tumor necrosis factor α in the serum of children vertically infected with HIV-1
33. Correlation of viral load and CD8 T lymphocyte with development of neurological manifestations in vertically HIV-infected infants. A prospective longitudinal study
34. The relationship between serum human immunodeficiency virus type 1 (HIV-1) RNA level. CD4 lymphocyte percent, and long-term mortality risk in HIV-1-infected children
35. Predictive markers of clinical outcome in vertically HIV-1 infected infants. A prospective longitudinal study
36. Prognostic markers of survival in infants younger than twelve months of age vertically infected by human immunodeficiency virus type-1
37. Serum levels of tumor necrosis factor-alpha (TNF-alpha) and soluble TNF receptors in human immunodeficiency virus type 1 infection-correlations to clinical, immunologic, and virologic parameters
38. Relationship of plasma HIV-RNA levels and levels of TNF-alpha and immune activation products in HIV infection
39. Control of T lymphocyte activation and IL-2 receptor expression by endogenously secreted lymphokines
40. Synergy of tumor necrosis factor with protein kinase C activators on T cell activation
41. Regulation of the immune response by nitric oxide differentially produced by T helper type 1 and T helper type 2 cells
42. Immunologic NO synthase: Elevation in severe AIDS dementia and induction by HIV-1 gp41
43. The role of tumour necrosis factor, interleukin-6, interferon-gamma and inducible nitric oxide synthase in the development and pathology of the nervous system
44. Host factors and the pathogenesis of HIV-induced disease
45. A Tat-induced auto-up-regulatory loop for superactivation of the human immunodeficiency virus type 1 promoter
46. HIV-1 induces tumour necrosis factor and IL-1 gene expression in primary human macrophages independent of productive infection
47. Role of cytokines in the pathogenesis of human immunodeficiency virus infection
48. Regulation of biosynthesis of nitric oxide
49. The antiviral role of nitric oxide
50. The antiviral effects of nitric oxide