Species difference in the disposition of liposomes among mice, rats, and rabbits: Allometric relationship and species dependent hepatic uptake mechanism

Pharmaceutical Research

Volumn 13, Issue 7, 1996, Pages 1049-1054

  Harashima, H ^a   Komatsu, S ^a   Kojima, S ^a   Yanagi, C ^a   Morioka, Y ^a   Naito, M ^b   Kiwada, H ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b NIIGATA UNIVERSITY   (Japan)

Author keywords

Drug delivery system; Liposomes; Pharmacokinetics; Species difference

Indexed keywords

LIPOSOME;

ALLOMETRY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG DISPOSITION; DRUG UPTAKE; INTRAVENOUS DRUG ADMINISTRATION; LIVER PERFUSION; MALE; MEAN RESIDENCE TIME; MOUSE; MULTIPLE REGRESSION; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; RABBIT; RAT; SPECIES DIFFERENCE;

ANIMALS; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; IMMUNOHISTOCHEMISTRY; KUPFFER CELLS; LIPOSOMES; LIVER; MICE; OPSONIN PROTEINS; RABBITS; RATS; RATS, WISTAR; SPECIES SPECIFICITY; SPLEEN;

EID: 0029739890     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016058724452     Document Type: Article

References (16)

1. E. F. Adolph. Quantitative relationship in the physiological constitutions of mammals. Science 109:579-585 (1949).
2. H. Boxenbaum. Interspecies variation in liver weight, hepatic blood flow, and antipyrine intrinsic clearance: Extraction of data to benzodiazepines and phenytoin. J. Pharmacokin. Biopharm. 8:165-176 (1980).
3. Y. Sawada, M. Hanano, Y. Sugiyama, and T. Iga. Prediction of the disposition of-lactam antibiotics in humans from pharmacokinetic parameters. J. Pharmacokin. Biopharm. 12:241-261 (1984).
4. J. Mordenti, S. A. Chen, J. A. Moore, B. L. Ferraiolo, and J. D. Green. Interspecies scaling of clearance and volume of distribution data for five therapeutic proteins. Pharm. Res. 8:1351-1359 (1991).
5. A. Gabizon and D. Papahadjopoulos. Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors. Proc. Natl. Acad. Sci. USA 85:6949-6953 (1988).
6. R. L. Juliano and D. Stamp. The effect of particle size and charge on the clearance rates of liposomes and liposomes encapsulated drugs. Biochem. Biophys. Res. Comm. 63:651-658 (1975).
7. P. L. Beaumier and K. J. Hwang. Effects of liposomes size on the degradation of bovine brain sphingomyelin/cholesterol liposomes in the mouse liver. Biochim. Biophys. Acta 731:23-30 (1983).
8. T. M. Allen and C. Hansen. Pharmacokinetics of stealth versus conventional liposomes: effect of dose. Biochim. Biophys. Acta 1068:133-141 (1991).
9. H. Harashima, C. Yamane, Y. Kume, and H. Kiwada. Kinetic analysis of AUC-dependent saturable clearance of liposomes: Mathematical description of AUC dependency. J. Pharmacokin. Biopharm. 21:299-308 (1993).
10. H. Harashima, K. Sakata, K. Funato, and H. Kiwada. Enhanced hepatic uptake of liposomes through complement activation depending on the size of liposomes. Pharm. Res. 11:402-406 (1994).
11. H. Harashima, Y. Sugiyama, T. Iga, and M. Hanano. Nonlinear tissue distribution of ouabain in rabbits. Drug Metab. Disp. 16:645-649 (1988).
12. J. T. P. Derksen, H. W. M. Morselt, and G. L. Scherphof. Procesing of different liposome markers after in vitro uptake of immunoglobulin-coated liposomes by rat liver macroph ages. Biochim. Biphys. Acta 931:33-40 (1987).
13. K. Yamaoka, Y. Tanigawara, T. Nakagawa, andT. Uno. Apharmacokinetic analysis program (MULTI) for microcomputer. J. Pharm. Dyn. 4:879-890 (1981).
14. Y. Isobe, S. Chen, P. K. Nakane, and W. R. Brown. Studies on translocation of immuno globulins across intestinal epithelium. I. Improvements in the peroxidase-labeled antibody method for application to study of human intestinal mucosa. Acta Histochem. Cytochem. 10:161-171 (1977).
15. K. Funato, R. Yoda, and H. Kiwada. Contribution of complement system on destabilization of liposomes composed of hydrogenated egg phosphatidylcholine in rat fresh plasma. Biochim. Biophys. Acta 1103:198-204 (1992).
16. H. Harashima, T. Hiraiwa, Y. Ochi, and H. Kiwada. Size dependent liposome degradation in blood: In vivolin vitro correlation by kinetic modeling. J. Drug Targeting 3:253-261 (1995).