Toward new designed proteins derived from bovine pancreatic trypsin inhibitor (BPTI): Covalent cross-linking of two 'core modules' by oxime-forming ligation

Bioconjugate Chemistry

Volumn 12, Issue 5, 2001, Pages 726-741

  Carulla, N ^a   Woodward, C ^b   Barany, G ^a  

^a University of Minnesota   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASSOCIATION REACTIONS; CHEMICAL SHIFT; CONFORMATIONS; CROSSLINKING; DIMERS; MAMMALS; MONOMERS; REACTION RATES; SULFUR COMPOUNDS; UREA;

BOVINE PANCREATIC TRYPSIN INHIBITORS; COVALENT CROSSLINKING; COVALENT LINKAGE; ENERGY; HYDROGEN EXCHANGE; LIGATION CHEMISTRY; OPTIMIZED SYNTHESIS; SECONDARY STRUCTURAL ELEMENTS; SYNTHESIS AND CHARACTERIZATIONS; Β-SHEET STRUCTURE;

PEPTIDES;

ANIMALIA; BOS TAURUS; BOVINAE;

EID: 0034809184     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc015518m     Document Type: Article

References (34)

1. Synthesis and Characterization of a β-Hairpin Peptide That Represents a 'Core Module' of Bovine Pancreatic Trypsin Inhibitor (BPTI)
2. The concentration dependence of the diffusion coefficient for Bovine Pancreatic Trypsin Inhibitor: A dynamic light scattering study of a small protein
3. A pulsed-field gradient NMR study of Bovine Pancreatic Trypsin Inhibitor Self-Association
4. Self-Association of Bovine Pancreatic Trypsin Inhibitor: Specific or nonspecific?
5. Facile synthesis of homogeneous artificial proteins
6. Unprotected peptides as building blocks for the synthesis of peptide dendrimers with oxime, hydrazone, and thiazolidine linkages
7. Natural peptides as building blocks for the synthesis of large protein-like molecules with hydrazone and oxime linkages
8. New protein mimetics: The zinc finger motif as a locked-in tertiary fold
9. Functional molecular thin films: Topological templates for the chemoselective ligation of antigenic peptides to self-assembled monolayers
10. Total chemical synthesis of a unique transcription factor-related protein: cMyc-Max
11. Cyclisation of totally unprotected peptides in aqueous solution by oxime formation
12. Analogues of oxytocin with an oxime bridge using chemoselective addressable building blocks
13. Preparation and application of the 5-(4-(9-fluorenylmethyoxycarbonyl)aminoethyl-3,5-dimethoxyphenoxy)valeric acid (PAL) handle for the solid-phase synthesis of c-terminal peptide amides under mild conditions
14. Solid-phase synthesis of Bovine Pancreatic Trypsin Inhibitor (BPTI) and two Aaalogues
15. Optimized methods for chemical synthesis of Bovine Pancreatic Trypsin Inhibitor (BPTI) analogues
16. Preparation and applications of polyethylene glycol-polystyrene graft resin supports for solid-phase peptide synthesis
17. Occurrence and minimization of cysteine racemization during stepwise solid-phase peptide synthesis
18. α-alloc temporary protection in solid-phase peptide synthesis. The use of amine-borane complexes as allyl scavengers
19. Disulfide bond formation in peptides
20. α-trifiuoroacetylation of N-terminal hydroxyamino acids: A new side reaction in peptide synthesis
21. A cleavage method which minimizes side reactions following fmoc solid-phase peptide synthesis
22. Functionalization of peptides and proteins by Aldehyde or Keto Groups
23. Construction of protein analogues by site-specific condensation of unprotected fragments
24. New cyclization reaction at the amino terminus of peptides and proteins
25. Reactions of the cyanate present in aqueous urea with amino acids and proteins
26. Determination of cyanate, and a study of its accumulation in aqueous solutions of urea
27. 1H chemical shifts obtained as a function of temperature and trifluoroethanol concentration for the peptide series GGXGG
28. 15N random coil nmr chemical shifts of the common amino acids. I. Investigations of nearest-neighbor effects
29. Dynamic structure of a highly ordered β-sheet molten globule: Multiple Conformations with a stable core
30. Local fluctuations and global unfolding of partially folded BPTI detected by NMR
31. A residue-specific NMR view of the non-cooperative unfolding of a molten globule
32. MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures
33. IUPAC-IUB commission of biochemical nomenclature