Changes in chromatin conformation during radiation-induced apoptosis in human lymphocytes

Radiation Research

Volumn 156, Issue 4, 2001, Pages 355-364

  Belyaev, I Y ^a   Czene, S ^a   Harms Ringdahl, M ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

DNA FRAGMENT;

APOPTOSIS; ARTICLE; CELL CYCLE G0 PHASE; CHROMATIN CONDENSATION; CHROMATIN STRUCTURE; CONTROLLED STUDY; DNA STRAND BREAKAGE; DOSE RESPONSE; DOSE TIME EFFECT RELATION; FLUORESCENCE; GAMMA RADIATION; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; NORMAL HUMAN; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PULSED FIELD GEL ELECTROPHORESIS; RADIATION INJURY; VISCOSITY;

EID: 0034807583     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/0033-7587(2001)156[0355:CICCDR]2.0.CO;2     Document Type: Article

References (42)

1. Social controls on cell survival and cell death
2. Apoptosis in the pathogenesis and treatment of disease
3. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
4. Topoisomerase II-reactive chemotherapeutic drugs induce apoptosis in thymocytes
5. Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation
6. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
7. Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death)
8. Identification of deoxyribonuclease II as an endonuclease involved in apoptosis
9. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
10. A calcium-dependent nuclease from apoptotic rat thymocytes is homologous with cyclophilin. Recombinant cyclophilins A, B, and C have nuclease activity
11. Mechanisms of induction of apoptotic DNA fragmentation
12. High sensitivity of chromatin conformational state of human leukocytes to low-dose X-rays
13. Effects of gamma rays in the 0.5-50-cGy range on the conformation of chromatin in mammalian cells
14. Relationship between radiation induced adaptive response in human fibroblasts and changes in chromatin conformation
15. Radial migration of DNA molecules in cylindrical flow
16. Radial migration of DNA molecules in cylindrical flow. II Circles and the effect of non-gaussian polymer statistics
17. Physical model of the anomalous viscosity time dependence in solutions of high-polymer DNA-protein complexes
18. Effects of ethidium bromide on DNA loop organization in human lymphocytes measured by anomalous viscosity time dependence and single cell gel electrophoresis
19. Effects of zero magnetic field on the conformation of chromatin in human cells
20. Effects of weak ELF on E. coli cells and human lymphocytes: Role of genetic, physiological and physical parameters
21. RBE for the induction of apoptosis in human peripheral lymphocytes exposed in vitro to high-LET radiation generated by accelerated nitrogen ions
22. Morphological and biochemical criteria of apoptosis
23. The comet assay: Mechanisms and technical considerations
24. DNA damage and repair with age in individual human lymphocytes
25. UV- and gamma-irradiation-induced DNA single-strand breaks and their repair in human blood granulocytes and lymphocytes
26. Detection and repair of single-strand breaks in nuclear DNA
27. Slow repair of X-ray-induced DNA damage in rat 9L cells in vitro analyzed by viscoelastometry
28. The reconstitution of higher-order DNA structure after X-irradiation of mammalian cells
29. Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells
30. A domain model for eukaryotic DNA organisation: A molecular basis for cell differentiation and chromosome evolution
31. Scaffold-associated regions: Cis-acting determinants of chromatin structural loops and functional domains
32. Specificity and functional significance of DNA interaction with the nuclear matrix: New approaches to clarify the old questions
33. The specificity of human lymphocyte nucleolar DNA long-range fragmentation by endogenous topoisomerase II and exogenous Bal 31 nuclease depends on cell proliferation status
34. DNA damage produced by ionizing radiation in mammalian cells: Identities, mechanisms of formation, and repairability
35. The effect of X-rays and neutrons on lymphocyte death and transformation
36. RBE of fast neutrons for apoptosis in mouse thymocytes
37. 60Co gamma-rays in human peripheral blood lymphocytes
38. Genetic processes and the problem of the target in chromosomal mutagenesis
39. The kinetics of postirradiation chromatin restitution as revealed by chromosome aberrations detected by premature chromosome condensation and fluorescence in situ hybridization
40. 2 lymphocytes after low-LET radiation
41. DNA fragmentation during apoptosis is caused by frequent single-strand cuts
42. DNA damage and cell killing by camptothecin and its derivative in human leukemia HL-60 cells