Long-term persistence and reactivation of T cell memory in the lung of mice infected with respiratory syncytial virus

European Journal of Immunology

Volumn 31, Issue 9, 2001, Pages 2574-2582

  Ostler, Tobias ^a   Hussell, Tracy ^b   Surh, Charles D ^c   Openshaw, Peter ^a   Ehl, Stephan ^a,d  

^a UNIVERSITY OF FREIBURG   (Germany)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

CD4+ T cell; CD8+ T cell; Lung; Memory; Respiratory syncytial virus

Indexed keywords

CD4 ANTIGEN; CD69 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; NEUTRALIZING ANTIBODY; PADGEM PROTEIN; PEPTIDE;

ADOPTIVE TRANSFER; ARTICLE; CELL DIVISION; CELL SPECIFICITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE RELEASE; LUNG; LUNG INFECTION; LYMPH NODE; LYMPHOCYTE ACTIVATION; LYMPHOID TISSUE; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECALL; REINFECTION; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; T LYMPHOCYTE; TARGET ORGAN; VIRUS INFECTION;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS, VIRAL; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; IMMUNOLOGIC MEMORY; INTERFERON TYPE II; KINETICS; LUNG; LUNG DISEASES; LYMPH NODES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES;

EID: 0034807184     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200109)31:9<2574::AID-IMMU2574>3.0.CO;2-V     Document Type: Article

References (24)

1. Cytotoxic T cells clear virus but augment lung pathology in mice infected with respiratory syncytial virus
2. Role of T lymphocyte subsets in the pathogenesis of primary infection and rechallenge with respiratory syncytial virus in mice
3. The 22-kilodalton protein of respiratory syncytial virus is a major target for Kd-restricted cytotoxic T lymphocytes from mice primed by infection
4. Anatomical environment as a determinant in viral immunity
5. Cellular events in the lymph node and lung of mice with influenza. Consequences of depleting CD4+ T cells
6. Partitioning of responder CD8+ T cells in lymph node and lung of mice with Sendai virus pneumonia by LECAM-1 and CD45RB phenotype
7. Recruitment and proliferation of CD8+ T cells in respiratory virus infections
8. Functionally distinct T cells in three compartments of the respiratory tract after influenza virus infection
9. Systemic T cell expansion during localized viral infection
10. Virus-specific CD8+ T cells in primary and secondary influenza pneumonia
11. In vivo proliferation of naive and memory influenza-specific CD8(+) T cells
12. T cell redistribution kinetics after secondary infection of BALB/c mice with respiratory syncytial virus
13. A novel approach to visualize polyclonal virus-specific CD8 T cells in vivo
14. Cytotoxic T cells specific for a single peptide on the M2 protein of respiratory syncytial virus are the sole mediators of resistance induced by immunization with M2 encoded by a recombinant vaccinia virus
15. Induction of bystander T cell proliferation by viruses and type I interferon in vivo
16. The traffic of lymphocytes
17. Th1 and Th2 cytokine induction in pulmonary T cells during infection with respiratory syncytial virus
18. Cytotoxic T-lymphocyte precursor frequencies in BALB/c mice after acute respiratory syncytial virus (RSV) infection or immunization with a formalin-inactivated RSV vaccine
19. Activated antigen-specific CD8+ T cells persist in the lungs following recovery from respiratory virus infections
20. Protection from respiratory virus infections can be mediated by antigen- specific CD4(+) T cells that persist in the lungs
21. Visualizing the generation of memory CD4 T cells in the whole body
22. Preferential localization of effector memory cells in nonlymphoid tissue
23. Mucosal T cell distribution during infection with respiratory syncytial virus
24. Activated T cells from draining lymph nodes and an effector site differ in their responses to TCR stimulation