Evidence that spinal segmental nitric oxide mediates tachyphylaxis to peripheral local anesthetic nerve block

Acta Anaesthesiologica Scandinavica

Volumn 45, Issue 8, 2001, Pages 945-953

  Wang, C ^a,b   Sholas, M G ^a   Berde, C B ^a   Dicanzio, J ^a   Zurakowski, D ^a,b   Wilder, R T ^a,b,c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c MAYO CLINIC   (United States)

Author keywords

Anesthetics, local: 2 chloroprocaine; Dose response relationship, drug; Injections, spinal; NG nitroarginine methyl ester; Nitric oxide; Sciatic nerve; Tachyphylaxis

Indexed keywords

CHLOROPROCAINE; LOCAL ANESTHETIC AGENT; N(G) NITRO DEXTRO ARGININE METHYL ESTER; NITRIC OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENZYME INHIBITION; HYPERALGESIA; NERVE BLOCK; NONHUMAN; PERIPHERAL NERVE; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SECOND MESSENGER; SENSORY STIMULATION; SPINAL CORD TRANSSECTION; TACHYPHYLAXIS; WITHDRAWAL REFLEX;

ANESTHETICS, LOCAL; ANIMALS; ARGININE; MALE; NERVE BLOCK; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; PROCAINE; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD; TACHYPHYLAXIS;

EID: 0034804031     PISSN: 00015172     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-6576.2001.450805.x     Document Type: Article

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