Uterine relaxant effects of cyclooxygenase-2 inhibitors in vitro

Obstetrics and Gynecology

Volumn 98, Issue 4, 2001, Pages 563-569

  Slattery, Michael M ^a   Friel, Anne M ^a   Healy, David G ^a   Morrison, John J ^a  

^a UNIVERSITY HOSPITAL GALWAY   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

CELECOXIB; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; MELOXICAM; NIMESULIDE;

ADULT; ARTICLE; CESAREAN SECTION; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; DRUG SELECTIVITY; FEMALE; HUMAN; HUMAN TISSUE; HYSTERECTOMY; IN VITRO STUDY; LABOR; MUSCLE TONE; MYOMETRIUM; PREGNANCY; PRIORITY JOURNAL; UTERUS CONTRACTILITY; UTERUS RELAXATION;

ADULT; CESAREAN SECTION; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; FEMALE; HUMANS; HYSTERECTOMY; ISOENZYMES; LABOR, OBSTETRIC; MEMBRANE PROTEINS; MIDDLE AGED; MYOMETRIUM; PREGNANCY; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PYRAZOLES; SULFONAMIDES; THIAZINES; THIAZOLES; UTERINE CONTRACTION;

EID: 0034802924     PISSN: 00297844     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0029-7844(01)01522-8     Document Type: Article

References (18)

1. Prostaglandins and parturition
2. Characterisation of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2
3. Expression of cyclo-oxygenase types-1 and -2 in human fetal membranes throughout pregnancy
4. COX-2 inhibitors
5. The effect of acetylsalicylic acid and indomethacin on the catecholamine- and oxytocin-induced contractility and prostaglandin (6-keto-PGF1 alpha, PGF2 alpha)-production of human pregnant myometrial strips
6. Neonatal complications after administration of indomethacin for preterm labor
7. Expression of cyclo-oxygenase types-1 and -2 in human myometrium throughout pregnancy
8. In vivo administration of nimesulide, a selective PGHS-2 inhibitor, increases in vitro myometrial sensitivity to prostaglandins while lowering sensitivity to oxytocin
9. Efficacy of the selective prostaglandin synthase type 2 inhibitor nimesulide in blocking basal prostaglandin production and delaying glucocorticoid-induced premature labor in sheep
10. Use of a cyclo-oxygenase type-2-selective non-steroidal anti-inflammatory agent to prevent preterm labour
11. Tocolytic effect of the cyclooxygenase-2 inhibitor, meloxicam: Studies on uterine contractions in the rat
12. Celecoxib, a selective cyclooxygenase-2 inhibitor for the treatment of rheumatoid arthritis and osteoarthritis
13. 2+ channel current in myometrial smooth muscle from pregnant women
14. The effects of potassium channel openers on isolated human myometrium before and after the onset of labor
15. Effect of parathyroid hormone-related peptide (PTHrP) on human and rat myometrial contractility in vitro
16. In vitro comparison of four tocolytic agents, alone and in combination
17. Effects of nitric oxide (NO) substrate, NO donor compounds and NO synthase inhibitors on contractions of isolated human pregnant myometrium
18. Neonatal end-stage renal failure associated with maternal ingestion of cyclo-oxygenase-type-1 selective inhibitor nimesulide as tocolytic