In vivo administration of nimesulide, a selective PGHS-2 inhibitor, increases in vitro myometrial sensitivity to prostaglandins while lowering sensitivity to oxytocin

Journal of the Society for Gynecologic Investigation

Volumn 5, Issue 6, 1998, Pages 296-299

  Baguma Nibasheka, Mark ^a   Nathanielsz, Peter W ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

Myometrium; Nimesulide; Oxytocin; Prostaglandins; Sheep

Indexed keywords

CYCLOOXYGENASE 2 INHIBITOR; ESTRADIOL; NIMESULIDE; OXYTOCIN; PROSTAGLANDIN; PROSTAGLANDIN E2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DRUG MECHANISM; FEMALE; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; SHEEP; SIGNAL TRANSDUCTION; TISSUE PREPARATION; UTERUS CONTRACTILITY;

ANIMALS; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DINOPROST; DINOPROSTONE; ESTRADIOL; FEMALE; ISOENZYMES; MYOMETRIUM; OVARIECTOMY; OXYTOCIN; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROSTAGLANDINS; SHEEP; SULFONAMIDES; UTERINE CONTRACTION;

EID: 0032213462     PISSN: 10715576     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1071-5576(98)00031-8     Document Type: Article

References (12)

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