Factors affecting prostacyclin receptor agonist efficacy in different cell types

Cellular Signalling

Volumn 13, Issue 11, 2001, Pages 841-847

  Kam, Yiu Wing ^a   Chow, Kevin B S ^a   Wise, Helen ^a  

^a and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

Author keywords

IP receptor; Neuroblastoma cells; Partial agonists; Prostacyclin; Receptor coupling

Indexed keywords

2 [3 [2 (4,5 DIPHENYL 2 OXAZOLYL)ETHYL]PHENOXY]ACETIC ACID; [3 [4 (4,5 DIPHENYL 2 OXAZOLYL) 5 OXAZOLYL]PHENOXY]ACETIC ACID; ADENYLATE CYCLASE; BMY 42393; CICAPROST; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL PHOSPHATE; ISOPROTEIN; OCTIMIBATE; PERTUSSIS TOXIN; PROSTACYCLIN DERIVATIVE; PROSTACYCLIN RECEPTOR; PROSTANOID; PROTEIN KINASE C; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; TRITIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL TYPE; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; ENZYME ACTIVITY; ENZYME INHIBITION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INHIBITION KINETICS; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING;

ACETATES; ADENYLATE CYCLASE TOXIN; ANIMALS; CHO CELLS; CRICETINAE; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; EPOPROSTENOL; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; IMIDAZOLES; OXAZOLES; PERTUSSIS TOXIN; PHENOXYACETATES; PHOSPHOLIPASE C; RECEPTORS, EPOPROSTENOL; RECEPTORS, PROSTAGLANDIN; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; VIRULENCE FACTORS, BORDETELLA;

CRICETINAE; CRICETULUS GRISEUS;

EID: 0034802914     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0898-6568(01)00210-8     Document Type: Article

References (36)