Characterization of prostanoid receptor-evoked responses in rat sensory neurones

British Journal of Pharmacology

Volumn 124, Issue 3, 1998, Pages 513-523

  Smith, Jacqueline A M ^a   Amagasu, Shanti M ^a   Eglen, Richard M ^a   Hunter, John C ^a   Bley, Keith R ^a  

^a ROCHE BIOSCIENCE   (United States)

Author keywords

Cyclic AMP; Dorsal root ganglia; F 11; Grease gap; Prostacyclin; Prostanoid receptors; Sensory neurones; Vagus nerve

Indexed keywords

ADENYLATE CYCLASE; CARBACYCLIN; CICAPROST; CYCLIC AMP; FORSKOLIN; ILOPROST; INOSITOL PHOSPHATE; PHORBOL DIBUTYRATE; PHOSPHOLIPASE C; PROSTACYCLIN; PROSTAGLANDIN D2; PROSTAGLANDIN E2; PROSTAGLANDIN F2 ALPHA; PROSTANOID RECEPTOR; THROMBOXANE A2; UNCLASSIFIED DRUG; [3 [4 (4,5 DIPHENYL 2 OXAZOLYL) 5 OXAZOLYL]PHENOXY]ACETIC ACID;

ANIMAL CELL; ARTICLE; BIOCHEMISTRY; CANCER CELL CULTURE; CONTROLLED STUDY; DEPOLARIZATION; DRUG POTENCY; EXCITATION; HYPERALGESIA; MOUSE; NEUROBLASTOMA; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORY NERVE; SENSORY NERVE CELL; SPINAL GANGLION; TISSUE CULTURE; VAGUS NERVE;

EID: 0031747692     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701853     Document Type: Article

References (73)

1. BERKENKOPF, J.W. & WEICHMAN, B.M. (1998). Production of prostacyclin in mice following intraperitoneal injection of acetic acid, phenylbenzoquinone and zymosan: its role in the writhing response. Prostaglandins, 36, 693-707.
2. BEVAN, S. & GEPPETTI, P. (1994). Protons: small stimulants of capsaicin-sensitive sensory nerves. Trends Neurosci., 17, 509-512.
3. 2-induced activation and sensitization of articular mechanoreceptors. Neurosci. Lett., 124, 5-8.
4. 2, and cicaprost on the discharge of articular sensory receptors in vitro. Brain Res., 611, 103-107.
5. BLEY, K.R., EGLEN, R.M. & WONG, E.H.F. (1994). Characterization of 5-hydroxytryptamine-induced depolarizations in rat isolated vagus nerve. Eur. J. Pharmacol., 260, 139-147.
6. BOMBARDIERI, S., CATTANI, P., CIABATTONI, G., DI MUNNO, O., PASERO, G., PATRONO, C., PINCA, E. & PUGLIESE, F. (1981). The synovial prostaglandin system in chronic inflammatory arthritis: differential effects of steroidal and non-steroidal anti-inflammatory drugs. Br. J. Pharmacol., 73, 893-901.
7. BRODIE, M.J., HENSBY, C.N., PARKE, A. & GORDON, D. (1980). Is prostacyclin the major pro-inflammatory prostanoid in joint fluid? Life Sci., 27, 603-608.
8. BROWN, D.A. & MARSH, S.J. (1978). Axonal GABA-receptors in mammalian peripheral nerve trunks. Brain Res., 156, 187-191.
9. BROWN, E., KENDALL, D.A. & NAHORSKI, S.R. (1984). Inositol phospholipid hydrolysis in rat cerebral cortical slices. I. Receptor characterisation. J. Neurochem., 42, 1379-1387.
10. 4 receptors couple positively to tetrodotoxin-insensitive sodium channels in a sub-population of capsaicin-sensitive rat sensory neurons. J. Neurosci., 17, 7181-7189.
11. CODERRE, T.J. (1993). The role of excitatory amino acid receptors and intracellular messengers in persistent nociception after tissue injury in rats. Mol. Neurobiol., 7, 229-246.
12. COLEMAN, R.A., SMITH, W.L. & NARUMIYA, S. (1994). Classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes. Pharmacol. Rev., 46, 205-229.
13. 2-induced potentiation of bradykinin excitation in sensory neurons. Neuroscience, 66, 459-466.
14. DEVOR, M., WHITE, D.M., GOETZL, E.J. & LEVINE, J.D. (1992). Eicosanoids, but not tachykinins, excite C-fiber endings in rat sciatic nerve-end neuromas. NeuroReport, 3, 21-24.
15. DOHERTY, N.S., BEAVER, T.H., CHAN, K.Y., COUTANT, J.E. & WESTRICH, G.E. (1987). The role of prostaglandins in the nociceptive response induced by intraperitoneal injection of zymosan in mice. Br. J. Pharmacol., 91, 39-47.
16. 2) in the circulation of the dog. Br. J. Pharmacol., 64, Suppl. 414P.
17. 2 modulates the tetrodotoxin-resistant sodium current in neonatal rat dorsal root ganglion neurones via the cyclic AMP-protein kinase A cascade. J. Physiol., 495, 429-440.
18. FERREIRA, S.H. (1972). Prostaglandins, aspirin-like drugs and analgesia. Nature, 240, 200-203.
19. FERREIRA, S.H. (1979). Site of action of aspirin-like drugs and opioids. In Mechanisms of Pain and Analgesic Compounds, ed. Beers, R.F. Jr. & Bassett, E.G. pp. 309-321. New York: Raven Press.
20. 2+ dependent process. Prostaglandins, 18, 179-190.
21. 2. Prostaglandins, 16, 31-37.
22. 2+ influx in visceral afferent neurons. Brain Res., 345, 345-49.
23. FRANCEL,P.C., HARRIS, K. SMITH, M., FISHMAN, M.C., DAWSON, G. & MILLER, R.J. (1987). Neurochemical characteristics of a novel dorsal root ganglion X neuroblastoma hybrid cell line, F-11. J. Neurochem., 48, 1624-1631.
24. + current in nociceptors. Proc. Natl. Acad. Sci. U.S.A., 93, 1108-1112.
25. 2 antagonist and analgesic. Bioorgan. Medic. Chem. Lett., 4, 509-514.
26. 1α in the rat paw. Prostaglandins, 16, 153-162.
27. HINGTGEN, C.M., WAITE, K.J. & VASKO, M.R. (1995). Prostaglandins facilitate peptide release from rat sensory neurons by activating the adenosine 3′, 5′-cyclic monophosphate transduction cascade. J. Neurosci., 15, 5411-5419.
28. 1 on tissues which respond to bradykinin. Nature, 200, 892-895.
29. HOUSLAY, M.D. (1991). 'Crosstalk': a pivotal role for protein kinase C in modulating relationships betwen signal transduction pathways. Eur. J. Biochem., 195, 9-27.
30. h via adenylyl cyclase. Neuron, 3, 179-186.
31. IRELAND, S.J. & TYERS, M.B. (1987). Pharmacological characterization of 5-hydroxytryptamine-induced depolarization of the rat isolated vagus nerve. Br. J. Pharmacol., 90, 229-238.
32. 2. Agents Actions Suppl., 4, 204-212.
33. KIRIYAMA, M., USHIKUBI, F., KOBAYASHI, T., HIRATA, M., SUGIMOTO, Y. & NARUMIYA, S. (1997). Ligand binding specificities of the eight types and subypes of the mouse prostanoid receptors expressed in Chinese Hamster Ovary cells. Br. J. Pharmacol., 122, 217-224.
34. LAWRENCE, R.A., JONES, R.L. & WILSON, N.H. (1992). Characterization of receptors involved in the direct and indirect actions of prostaglandins E and I on the guinea-pig ileum. Br. J. Pharmacol., 105, 271-278.
35. LAWSON, S.N. (1992). Morphological and biochemical cell types of sensory neurons. In Sensory Neurons, Diversity, Development and Plasticity, ed. Scott, S. pp. 27-59. New York: Oxford UP.
36. LEUNG, E., MICHELSON, S., VILLARUBIA, C., PERKINS, L.A. & EGLEN, R.M. (1992). Analysis of concentration-response relationships by seemingly unrelated non-linear regression (SUNR) techniques. J. Pharmacol. Toxicol. Methods, 28, 209-216.
37. LINDSAY, R.M., EVISON, C.J. & WINTER, J. (1991). Culture of adult mammalian peripheral neurons. In Cellular Neurobiology: A Practical Approach, Vol. 1, ed. Wheal, H. & Chad, J. pp. 3-17. New York: Oxford UP.
38. 3 prostaglandin receptor subtypes. Prostaglandins, 52, 175-185.
39. MARSH, S.J., STANSFELD, C.E., BROWN, D.A., DAVEY, R. & MCCARTHY, D. (1987). The mechanism of action of capsaicin on sensory C-type neurons and their axons in vitro. Neuroscience, 23, 275-289.
40. 3H]iloprost Neuroscience, 65, 493-503.
41. 2 on testicular nociceptor activities studied in vitro. Naunyn-Schmiedeberg's Arch. Pharmacoi. 344, 368-376.
42. 2. J. Immunol., 155, 4437-4444.
43. MURATA, T., USHIKUBI, F., MATSUOKA, T., HIRATA, M., YAMASAKI, A., SUGIMOTO, Y., ICHIKAWA, A , AZE, Y., TANAKA, T., YOSHIDE, N., UONO, A., OH-ISHI, S. & NARUMIYA, S. (1997). Altered pain perception and inflammatory response in mice lacking prostacyclin receptor. Nature, 388, 678-682.
44. NAMBA, T., OIDA, H., SUGIMOTO, Y., KAKIZUKA, A., NEGISHI, M., ICHIKAWA, A. & NARUMIYA, S. (1994). cDNA cloning of a mouse prostacyclin receptor. J. Biol. Chem., 269, 9986-9992.
45. 2 receptors mediate different effects on synaptically evoked potential of the rat superior cervical ganglion. Neurosci. Lett., 88, 100-106.
46. NICOL, G.D., VASKO, M.R. & EVANS, A.R. (1997). Prostaglandins suppress an outward potassium current in embryonic rat sensory neurons. J. Neurophysiol., 55, 167-176.
47. OIDA, H., NAMBA, T., SUGIMOTO, Y., USHIKUBI, F., OHISHI, H., ICHIKAWA, A. & NARUMIYA, S. (1995). In situ hybridization studies of prostacyclin receptor mRNA expression in various mouse organs. Br. J. Pharmacol., 116, 2828-2837.
48. PAINTAL, A.S. (1963). Vagal afferent fibers. Ergebn. Physiol., 52, 74-156.
49. PARKER, R.B. & WAUD, D.R. (1971). Pharmacological estimation of drug-receptor dissociation constants. Statistical evaluation. I. Agonists. J. Pharmacol. Exp. Ther., 177, 1-12.
50. PIERCE, K.L., GIL, D.W., WOODWARD, D.F. & REGAN, J.W. (1995). Cloning of human prostanoid receptors. Trends Pharmacol. Sci., 16, 253-256.
51. PITCHFORD, S. & LEVINE, J.D. (1991). Prostaglandins sensitise nociceptors in cell culture. Neurosci. Lett., 132, 105-108.
52. PLATIKA, D., BOULOS, M.H., BAIZER, L, & FISHMAN, M.C. (1985). Neuronal traits of clonal cell lines derived by fusion of dorsal root ganglia neurons with neuroblastoma cells. Proc. Natl. Acad. Sci. U.S.A., 82, 3499-3503.
53. 2 blocks inflammation, hyperalgesia and interleukin 6 production in vivo. J. Exp. Med., 184, 883-891.
54. RANG, H.P. & RITCHIE, J.M. (1988). Depolarization of nonmyelinated fibers of the rat vagus nerve produced by activation of protein kinase C. J. Neurosci., 8, 2606-2617.
55. 2. J. Appl. Physiol., 58, 1823-1831.
56. RUEFF, A. & DRAY, A. (1993). Sensitization of peripheral afferent fibres in the in vitro neonatal rat spinal cord-tail by bradykinin and prostaglandins. Neuroscience, 54, 527-535.
57. 2. J. Physiol., 403, 91-104.
58. 2. Neuroscience, 50, 237-247.
59. 2+ concentration in the human erythroleukemia cell line, HEL, via pertussin toxin-insensitive G-proteins. Eicosanoids, 5, Suppl: S10-2.
60. SEILER, S.M., BRASSARD, C.L., FEDERICI, M.E., ROMINE, J. & MEANWELL, N.A. (1997). [3-[4[(4,5-diphenyl-2-oxazolyl)-5-oxazolyl]phenoxy]acetic acid is a potent non-prostanoid prostacyclin partial agonist: effects on platelet aggregation, adenylyl cyclase, cyclic AMP levels, protein kinase, and iloprost binding. Prostaglandins, 53, 21-35.
61. 2 antagonists. Adv. Prostaglandin Thrombox. Res., 6, 493-496.
62. + conductance in rat optic nerve axons. Proc. Natl. Acad. Sci. U.S.A., 90, 6976-6980.
63. TAIWO, Y.O. & LEVINE, J.D. (1988). Characterization of the arachidonic acid metabolites mediating bradykinin and noradrenaline hyperalgesia. Brain Res., 458, 402-406.
64. TAKECHI, H., MATSUMURA, K., WATANABE, Y., KATO. K., NOYORI, R., SUZUKI, M. & WATANABE, Y. (1996). A novel subtype of the prostacyclin receptor expressed in the central nervous system. J. Biol. Chem., 271, 5901-5906.
65. TONUSSI, C.R. & FERREIRA, S.H. (1992). Rat-knee carrageenan incapacitation test: an objective screen for central and peripheral analgesics. Pain, 48, 421-427.
66. TREZISE, D.J., KENNEDY, I. & HUMPHREY, P.P.A. (1993). Characterization of purinoceptors mediating depolarization of rat isolated vagus nerve. Br. J. Pharmacol., 110, 1055-1060.
67. TYERS, M.B. & HAYWOOD, H. (1979). Effects of prostaglandins on peripheral nociceptors in acute inflammation. Agents Actions Suppl., 6, 65-78.
68. UNDEM, B.J. & WEINREICH, D. (1993). Electrophysiological properties and chemosensitivity of guinea pig nodose ganglion neurons in vitro. J. Autonom. Nervous System, 44, 17-34.
69. USHIKUBI, F., HIRATA, M. & NARUMIYA, S. (1995). Molecular biology of prostanoid receptors: an overview. J. Lipid Mediators Cell Signal., 12, 343-359.
70. VASSAUX, G., GAILLARD, D., AILHAUD, G. & NEGREL, R. (1992). Prostacyclin is a specific effector of adipose cell differentiation. J. Biol. Chem., 268, 11092-11097.
71. WATANABE, T., YATOMI, Y., SUNAGA, S, MIKI, I., ISHII, A., NAKAO, A., HIGASHIHARA, M., SEYAMA, Y., OGURA, M., SAITO, H., KUROKAWA, K. & SHIMIZU, T. (1991). Characterization of prostaglandin and thromboxane receptors expressed on a megakaryoblastic leukemia cell line, MEG-01s. Blood, 78, 2328-2336.
72. 2. Agents Actions Suppl., 32, 107-111.
73. WISE, H. & JONES, R.L. (1996). Focus on prostacyclin and its novel mimetics. Trends Pharmacol. Sci., 17, 17-21.