Effects of nipradilol, a nitric oxide-releasing β-adrenoceptor blocking agent, on phosphoenolpyruvate carboxykinase gene transcription in a rat hepatoma cell line

Japanese Journal of Pharmacology

Volumn 87, Issue 1, 2001, Pages 83-85

  Yamauchi, K ^a   Nakajima, K ^a   Ikeo, S ^a   Nishimura, Y ^a   Komatsu, M ^a   Aizawa, T ^a   Hashizume, K ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Dexamethasone; Nipradilol; Phosphoenolpyruvate carboxykinase

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DEXAMETHASONE; GUANYLATE CYCLASE; METHYLENE BLUE; NIPRADILOL; NITRIC OXIDE; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); TIMOLOL;

ANIMAL CELL; ARTICLE; CELL LINE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME INHIBITION; GENETIC TRANSCRIPTION; HEPATOMA CELL; LIVER CELL; NONHUMAN; RAT;

EID: 0034800120     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.87.83     Document Type: Article

References (13)

1. New insights in steroid diabetes
2. Contribution of cyclic GMP generation to the relaxation by nipradilol in the rabbit aorta
3. Nipradilol: A β-adrenoceptor antagonist with nitric oxide-releasing action
4. Impairment of endothelium dependent relaxation in the diabetic rat heart: Mechanisms and implications
5. Excessive NO production does not account for inhibition of hepatic glucogenesis in endotoxemia
6. Insulin regulation of phosphoenolpyruvate carboxykinase gene expression does not require activation of the Ras/mitogen-activated protein kinase signaling pathway
7. Phosphoenolpyruvate carboxykinase (GTP) gene transcription and hyperglycemia are regulated by glucocorticoids in genetically obese db/db transgenic mice
8. Mechanism of the impairment of the glucagon-stimulated phosphoenolpyruvate carboxy-kinase gene expression by interleukin-6 in rat hepatocytes: Inhibition of the increase in cyclic 3′,5′ adenosine monophosphate and the downstream cyclic 3′,5′ adenosine monophosphate action
9. Glycine N-methyl-transferase is a mediator of cytochrome P4501A1 gene expression
10. β-Adrenergic receptor blockade in hypertension, past, present and future
11. Methylene blue inhibition of oestradiol-induced increase of ceruloplasmin serum levels in rats
12. Canine retinal arterial and arteriolar dilatation induced by nipradilol, a possible glaucoma therapeutic
13. The importance of nitric oxide in the cytokine-induced inhibition of glucose formation by cultured hepatocytes incubated with insulin, dexamethasone, and glucagon