Unravelling mechanisms of action of angiotensin II on cardiorespiratory function using in vivo gene transfer

Acta Physiologica Scandinavica

Volumn 173, Issue 1, 2001, Pages 127-137

  Paton, J F R ^a   Boscan, P ^a   Murphy, D ^a   Kasparov, S ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Adenoviral vectors; AT1 receptors; Endothelial nitric oxide synthase; Nucleus of the solitary tract

Indexed keywords

4 AMINOBUTYRIC ACID; ANGIOTENSIN; CALCIUM ION; MUTANT PROTEIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ADENOVIRUS; CALCIUM CELL LEVEL; ENDOTHELIUM; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ESSENTIAL HYPERTENSION; GENE TRANSFER; GENETIC TRANSFECTION; HEART FAILURE; HEART FUNCTION; NERVE CELL; NONHUMAN; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RESPIRATORY FUNCTION; REVIEW; SOLITARY TRACT NUCLEUS;

ADENOVIRIDAE; ANGIOTENSIN II; ANIMALS; BAROREFLEX; GENE TRANSFER TECHNIQUES; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTORS, ANGIOTENSIN; SOLITARY NUCLEUS;

EID: 0034798257     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201X.2001.00898.x     Document Type: Review

References (42)

1. Functional interactions between angiotensin II and substance P in the dorsal medulla
2. Anatomy of the lower brainstem
3. Baroreflex inhibition of cardiac sympathetic outflow is attenuated by angiotensin II in the solitary tract nucleus
4. Angiotensin II-like activity in circulating arterial blood in immature and adult rabbits
5. Endothelial nitric oxide synthase. N-terminal myristoylation determines subcellular localization
6. Angiotensin II attenuates baroreflexes at nucleus tractus solitarius of rats
7. Increased expression of angiotensin peptides in the brain of transgenic hypertensive rats
8. Morphological and electrophysiological properties of neurones in the dorsal vagal complex of the rat activated by arterial baroreceptors
9. ANG II receptor blockade and arterial baroreflex regulation of renal nerve activity in cardiac failure
10. Angiotensin II: A peptidergic neurotransmitter in central autonomic pathways
11. Volume transmission in transmitter peptide costoring neurons in the medulla oblongata
12. Increased concentration of angiotensin II binding sites in selected brain areas of spontaneously hypertensive rats
13. Tetracycline-regulated transgene expression in hippocampal neurones following transfection with adenoviral vectors
14. Switching transgene expression in the brain using an adenoviral tetracycline-regulatable system
15. Quantitative autoradiography of angiotensin II receptors in the rat solitary-vagal area: Effects of nodose gangionectomy or sinoaortic denervation
16. A role for endothelial NO synthase in LTP revealed by adenovirus-mediated inhibition and rescue
17. Changes in baroreceptor vagal reflex performance in the developing rat
18. Differential effects of angiotensin II in the nucleus tractus solitarius - II. Plausible neuronal mechanisms
19. Angiotensin II receptors within the nucleus of the solitary tract attenuate the baroreceptor vagal reflex in pre-weaned rats
20. The pharmacologic alteration of renin release
21. Oligomerization of endothelial nitric oxide synthase. Evidence for a dominant negative effect of truncation mutants
22. Identification of covalently bound amino-terminal myristic acid in endothelial nitric oxide synthase
23. 2 receptor subtypes in the tonic inhibitory modulation of baroreceptor reflex response by endogenous angiotensins at the nucleus tractus solitarii in the rat
24. Central gain of the cardiac sympathetic afferent reflex in dogs with heart failure
25. Angiotensin II acts at AT1 receptors in the nucleus of the solitary tract to attenuate the baroreceptor reflex
26. Angiotensin II as a modulator of baroreceptor reflexes in the brainstem of conscious rats
27. Angiotensin II and nitric oxide: A question of balance
28. Effect of an antihypertensive drug on brain angiotensin II levels in renal and spontaneously hypertensive rats
29. A working heart-brainstem preparation of the mouse
30. Differential effects of angiotensin II on cardiovascular reflexes mediated by nucleus tractus solitarii I. A microinjection study
31. Sensory channel specific modulation in the nucleus of the solitary tract
32. Adeno viral vector demonstrates that angiotensin II induced depression of the cardiac baroreflex is mediated by endothelial nitric oxide synthase in the nucleus tractus solitarii
33. Lowering of hypertension by central saralasin in the absence of plasma renin
34. Levels of angiotensin and molecular biology of the tissue renin angiotensin systems
35. Antisense inhibition of hypertension: A new strategy for renin-angiotensin candidate genes
36. Interactions between Ang II, sympathetic nervous system, and baroreceptor reflexes in regulation of blood pressure
37. Release of immunoreactive angiotensin II from neuronal cultures: Adrenergic influences
38. Differential ontogeny of rat brain peptidases: Prenatal expression of enkephalin convertase and postnatal development of angiotensin converting enzyme
39. Brain angiotensin II contributes to the development of hypertension in Dahl-Iwai salt-sensitive rats
40. Localization of angiotensin II receptor-like immunoreactivity in catecholaminergic neurons of the rat medulla oblongata
41. Mapping tissue angiotensin-converting enzyme and angiotensin AT1, AT2 and AT4 receptors