A working heart-brainstem preparation of the mouse

Journal of Neuroscience Methods

Volumn 65, Issue 1, 1996, Pages 63-68

  Paton, Julian F R ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Cardiac vagal; Cardio respiratory; In vitro milieu; Intra arterially perfused; Intracellular; Phrenic; Sinus arrhythmia

Indexed keywords

ANIMAL TISSUE; ARTICLE; BRAIN STEM; CARDIOVASCULAR SYSTEM; CONTROLLED STUDY; FEMALE; INTRACELLULAR RECORDING; MALE; MOUSE; NONHUMAN; PHRENIC NERVE; PRIORITY JOURNAL; RESPIRATORY NERVE CELL;

EID: 0030009461     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-0270(95)00147-6     Document Type: Article

References (18)

1. Bard, P. (1961) Medical Physiology, 11th edn., Mosby, USA.
2. Fung, M.-L, Wang, W. and St. John, W.M. (1994) Medullary loci critical for expression of gasping in adult rats. J. Physiol., 480: 597-611.
3. Gilbey, M.P., Jordan, D., Richter, D.W. and Spyer, K.M. (1984) Synaptic mechanisms involved in the inspiratory modulation of vagal cardio-inhibitory neurones in the cat. J. Physiol., 356: 65-78.
4. Kangrga, I.M. and Loewy, A.D. (1994) Whole-cell patch-clamp recordings from visualized bulbospinal neurons in brainstem slices. Brain Res., 641: 181-190.
5. Kubin, L. and Davies, R.O. (1995) Central pathways of pulmonary and airway vagal afferents. In: J.A. Dempsey and A.I. Pack (Eds.), Regulation of Breathing, Marcel Dekker, New York, pp. 219-284.
6. McAllen, R.M. (1987) Central respiratory modulation of subretrofacial bulbospinal neurones in the cat. J. Physiol., 388: 533-545.
7. Onimaru, H., Arata, A. and Homma, I. (1990) Inhibitory synaptic input to the respiratory rhythm generator in the medulla isolated from newborn rats. Pflügers Arch., 417: 425-432.
8. Paton, J.F.R. (1995) A working heart brainstem preparation of the mouse. J. Physiol. (Abst.), 489: 155P.
9. Paton, J.F.R. and Richter, D.W. (1995a) Role of fast inhibitory synaptic mechanisms in respiratory rhythm generation in the maturing mouse. J. Physiol., 484.2: 505-521.
10. Paton, J.F.R and Richter, D.W. (1995b) Maturational changes in the respiratory rhythm generator of the mouse. Pflügers Arch., 430: 115-124.
11. Paton, J.F.R., Ramirez, J.-M. and Richter, D.W. (1994) Functionally intact in vitro preparation generating respiratory activity in neonatal and mature mammals. Pflügers Arch., 428: 250-260.
12. Pegg, D.E. and Farrant, J. (1969) Vascular resistance and edema in the isolated rabbit kidney perfused with a cell-free solution. Cryobiology, 6: 200-210.
13. Richter, D.W. (1982) Generation and maintenance of the respiratory rhythm. J. Exp. Physiol., 100: 93-107.
14. Ross, C., White, F.N., Brown, A.W. and Kolen, A. (1966) Regional blood flow in the rat. J. Appl. Physiol., 21: 1273-1275.
15. Siesjo, B.K. (1978). Brain Energy Metabolism. John Wiley, New York.
16. Smith, J.C., Ellenberger, H.H., Ballanyi, K., Richter, D.W. and Feldman, J.L. (1991a) Pre-Bötzinger complex: a brainstem region that may generate respiratory rhythm in mammals. Science, 254: 726-729.
17. Smith, J.C., Greer, J.L., Liu, G. and Feldman, J.L. (1991b) Neural mechanisms generating respiratory pattern in mammalian brainstem-spinal cord in vitro. I. Spatiotemporal patterns of motor and medullary neuron activity. J. Neurophysiol., 64: 1149-1169.
18. Sun, M-K., Young, B.S., Hackett, J.T. and Guyenet, P.G. (1988) Rostral ventrolateral medullary neurons with intrinsic pacemaker properties are not catecholaminergic. Brain Res., 451: 345-349.