Clinical features in women with polycystic ovaries: Relationships to insulin sensitivity, insulin gene VNTR and birth weight

Clinical Endocrinology

Volumn 55, Issue 4, 2001, Pages 439-446

  Michelmore, Katherine ^a   Ken Ong, Sam Mason ^b   Bennett, Simon ^c   Perry, Leslie ^d   Vessey, Martin ^a   Balen, Adam ^e   Dunger, David ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c Oxagen Limited   (United Kingdom)

^d ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^e LEEDS GENERAL INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACNE; ADULT; ALLELE; ARTICLE; BIOCHEMISTRY; BIRTH WEIGHT; BODY MASS; CLINICAL EXAMINATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; HIRSUTISM; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; MENSTRUAL IRREGULARITY; MULTICENTER STUDY; OVARY POLYCYSTIC DISEASE; PHENOTYPE; PRIORITY JOURNAL; TESTOSTERONE BLOOD LEVEL; ULTRASOUND;

ADOLESCENT; ADULT; ALLELES; BIOLOGICAL MARKERS; BIRTH WEIGHT; BODY CONSTITUTION; BODY MASS INDEX; FEMALE; HUMANS; INSULIN; INSULIN RESISTANCE; MINISATELLITE REPEATS; POLYCYSTIC OVARY SYNDROME;

EID: 0034797755     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.2001.01375.x     Document Type: Article

References (51)

1. Prevalence of polycystic ovaries in women with anovulation and idiopathic hirsutism
2. Menstrual irregularities are more common in adolescents with type 1 diabetes: Association with poor glycaemic control and weight gain
3. Polycystic ovary syndrome: The spectrum of the disorder in 1741 patients
4. Pathogenesis of polycystic ovary syndrome - The enigma unravels?
5. Human type 1 diabetes and the insulin gene: Principles of mapping polygenes
6. Association of insulin gene VNTR polymorphism with polycystic ovary syndrome
7. Measurement of insulin-like growth factor-II in physiological fluids and tissues. I. An improved extraction procedure and radioimmunoassay for human and rat fluids
8. Rapid isolation of eukaryotic DNA
9. Serum immunoreactive leptin concentrations in women with polycystic ovary syndrome
10. Circulating leptin concentrations in polycystic ovary syndrome: Relation to anthropometric and metabolic parameters
11. Increased plasma leptin levels are associated with fat accumulation in Japanese Americans
12. Ovarian volume in gynecologically healthy women using no contraception, or using IUD or oral contraception
13. How common are polycystic ovaries in normal women and what is their significance for the fertility of the population?
14. Serum immunoreactive-leptin concentrations in normal-weight and obese humans
15. Fetal growth, length of gestation, and polycystic ovaries in adult life
16. Women with polycystic ovary syndrome wedge resected in 1956-65: A long-term follow-up focusing on natural history and circulating hormones
17. Insulin resistance and the polycystic ovary syndrome: Mechanism and implications for pathogenesis
18. Association of the INS VNTR with size at birth
19. Body fat assessed from total body density and its estimation from skinfold thickness: Measurements on 481 men and women aged from 16 to 72 years
20. Transmission ratio distortion at the INS-IGF2 VNTR
21. Homeostasis model assessment as a clinical index of insulin resistance in type 2 diabetic patients treated with sulfonylureas
22. Clinical assessment of body hair growth in women
23. Polycystic ovary syndrome
24. The genetic basis of polycystic ovary syndrome
25. Is there a role for leptin in the endocrine and metabolic aberrations of polycystic ovary syndrome?
26. Histologic changes associated with oral contraceptive usage
27. The homeostasis model in the San Antonio heart study
28. Alterations in the insulin-like growth factor system during the menstrual cycle in normal women
29. Disturbances in insulin secretion and sensitivity in women with the polycystic ovary syndrome
30. High prevalence of polycystic ovaries and associated clinical, endocrine, and metabolic features in women with previous gestational diabetes mellitus
31. Analysis of parent-offspring trials provides evidence for linkage and association between the insulin gene and type 2 diabetes mediated exclusively through paternally transmitted class III variable number tandem repeat alleles
32. Precocious pubarche, hyperinsulinism, and ovarian hyperandrogenism in girls: Relation to reduced fetal growth
33. Exaggerated adrenarche and hyperinsulinism in adolescent girls born small for gestational age
34. The prevalence of polycystic ovaries in the hepatic glycogen storage diseases: Its association with hyperinsulinism
35. Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
36. Glucose tolerance and resistance to insulin-stimulated glucose uptake in men aged 70 years in relation to size at birth
37. Polycystic ovaries and associated clinical and biochemical features in young women
38. Prevalence of mutations in the insulin receptor gene in subjects with features of the type A syndrome of insulin resistance
39. Which measure of body fat distribution is best for epidemiologic research?
40. Metabolic lessons from the study of young adolescents with polycystic ovary syndrome. Is insulin the culprit?
41. The insulin gene VNTR, type 2 diabetes and birth weight
42. Thinness at birth and insulin resistance in adult life
43. Polycystic ovaries - A common finding in normal women
44. Reduced insulin secretion: An independent predictor of body weight gain
45. The effect of insulin and insulin-like growth factor-I on glucose transport in normal and small for gestational age fetal rats
46. Ultrasound appearance of the ovaries during the pill-free interval
47. Linkage and association of insulin gene VNTR regulatory polymorphism with polycystic ovary syndrome
48. A relationship between sex hormone binding globulin and dehydroepiandrosterone sulfate in normally menstruating females
49. Can weight gain in healthy, nonobese volunteers be predicted by differences in baseline plasma insulin concentration?
50. Whole genome amplification from a single cell: Implications for genetic analysis