Cloning and characterization of a novel zinc finger protein (MDZF) that is associated with monocytic differentiation of acute promyelocytic leukemia cells

Journal of Cancer Research and Clinical Oncology

Volumn 127, Issue 11, 2001, Pages 659-667

  Yuan, Zhenglong ^a   Huang, Xin ^a   Zhang, Weiping ^a   Zhang, Minghui ^a   Wan, Tao ^a   Cao, Xuetao ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Gene clonig; Leukemia; Monocytic differentiation; Novel molecule; Zinc finger protein

Indexed keywords

MESSENGER RNA; PROTEIN ANTIBODY; ZINC FINGER PROTEIN;

ACUTE MYELOBLASTIC LEUKEMIA; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CANCER CELL; CANCER GROWTH; CELL DIFFERENTIATION; CHROMOSOME 3; DENDRITIC CELL; GENE STRUCTURE; HEART; HUMAN; KIDNEY PARENCHYMA; LIVER; MOLECULAR CLONING; MYELOID LEUKEMIA; PLACENTA; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SKELETAL MUSCLE; TISSUE DISTRIBUTION;

EID: 0034792147     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004320100266     Document Type: Article

References (45)

1. The BTB/POZ domain: A new protein-protein interaction motif common to DNA- and actin-binding proteins
2. Immunobiology of dendritic cells
3. The POZ domain: A conserved protein-protein interaction motif
4. A switch in broad-complex zinc-finger isoform expression is regulated posttranscriptionally during the metamorphosis of Drosophila imaginal discs
5. Molecular cloning and characterization of a novel CXC chemokine macrophage inflammatory protein-2 gamma chemoattractant for human neutrophils and dendritic cells
6. In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As203) in the treatment of acute promyelocytic leukemia: As203 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins
7. Neutrophils and monocytes express high levels of PU.1 (Spi-1) but not Spi-B
8. Fusion between a novel Kruppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia
9. Temporal mapping of gene expression levels during the differentiation of individual primary hematopoietic cells
10. Recruitment of SMRT/N-CoR-mSin3A-HDAC-repressing complexes is nota general mechanism for BTB/POZ transcriptional repressors: The case of HIC-1 and gammaFBP-B
11. The BTB/POZ domain targets the LAZ3/BCL6 oncoprotein to nuclear dots and mediates homomerisation in vivo
12. Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/ BCL6 oncoprotein
13. The Drosophila Broad-Complex encodes a family of related proteins containing zinc fingers
14. Amino-terminal protein-protein interaction motif (POZ-domain) is responsible for activities of the promyelocytic leukemia zinc finger-retinoic acid receptor-alpha fusion protein
15. Differential expression of Broad-Complex transcription factors may forecast tissue-specific developmental rates during Drosophila metamorphosis
16. Related Articles Increased hepatic cell proliferation and lung abnormalities in mice deficient in CCAAT/enhancer binding protein alpha
17. Pattern formation in the limbs of Drosophila: Bric a brac is expressed in both a gradient and a wave-like pattern and is required for specification and proper segmentation of the tarsus
18. The tramtrack gene encodes a Drosophila finger protein that interacts with the ftz transcriptional regulatory region and shows a novel embryonic expression pattern
19. Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL
20. SMRT corepressor interacts with PLZF and with the PMLretinoic acid receptor alpha (RARalpha) and PLZF-RARalpha oncoproteins associated with acute promyelocytic leukemia
21. The BCL-6 POZ domain and other POZ domains interact with the co-repressors N-CoR and SMRT
22. The ZiN/POZ domain of ZF5 is required for both transcriptional activation and repression
23. Modulation of idarubicin-induced apoptosis in human acute myeloid leukemia blasts by all-trans retinoic acid, 1,25(OH)2 vitamin D3, and granulocyte-macrophage colony-stimulating factor
24. NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3)
25. Cloning and characterization of a novel zinc finger protein that associates with nuclear matrix
26. Comparison of the GAGA factor genes of Drosophila melanogaster and Drosophila virilis reveals high conservation of GAGA factor structure beyond the BTB/POZ and DNA-binding domains
27. Transcriptional activation of the human p21(WAF1/CIP1) gene by retinoic acid receptor. Correlation with retinoid induction of U937 cell differentiation
28. Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities
29. Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia
30. Alternative splicing and genomic structure of the AML1 gene involved in acute myeloid leukemia
31. Spi-1 is a putative oncogene in virally induced murine erythroleukaemias
32. Common defects of different retinoic acid resistant promyelocytic leukemia cells are persistent telomerase activity and nuclear body disorganization
33. The zinc finger transcription factor Egr-1 is essential for and restricts differentiation along the macrophage lineage
34. Downing JR AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
35. PU. 1 is not essential for early myeloid gene expression but is required for terminal myeloid differentiation
36. An alternative pathway for gene regulation by Myc
37. Destruction of Myc by ubiquitin-mediated proteolysis: Cancer-associated and transforming mutations stabilize Myc
38. Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages
39. Transcriptional regulation in myeloid cell differentiation
40. Subspecies-specific targeting mechanism of protein kinase C
41. Transcription factors, normal myeloid development, and leukemia
42. Impaired energy homeostasis in C/EBP alpha knockout mice
43. Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis
44. Tissue factors on acute promyelocytic leukemia and endothelial cells are differently regulated by retinoic acid, arsenic trioxide and chemotherapeutic agents
45. The BTB domain, round primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila