Phenylcoumaran benzylic ether and isoflavonoid reductases are a new class of cross-reactive allergens in birch pollen, fruits and vegetables

European Journal of Biochemistry

Volumn 268, Issue 20, 2001, Pages 5310-5320

  Karamloo, Fariba ^a   Wangorsch, Andrea ^b   Kasahara, Hiroyuki ^c   Davin, Laurence B ^c   Haustein, Dieter ^b   Lewis, Norman G ^c   Vieths, Stefan ^b  

^a SWISS INSTITUTE OF ALLERGY AND ASTHMA RESEARCH SIAF   (Switzerland)

^b PAUL EHRLICH INSTITUT   (Germany)

^c WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Birch pollen related food allergy; Cross reaction; Isoflavone reductase; Phenylcoumaran benzylic ether reductase; Plant defense

Indexed keywords

ALCOHOL DERIVATIVE; ALLERGEN; BLOOD CLOTTING FACTOR 10A; DEHYDRODICONIFERYL ALCOHOL; EPITOPE; FOOD ALLERGEN; HYBRID PROTEIN; IMMUNOGLOBULIN E; ISODIHYDRODEHYDRODICONIFERYL ALCOHOL; ISOFLAVONOID; MONOCLONAL ANTIBODY; OXIDOREDUCTASE; PHENYLCOUMARAN BENZYLIC ETHER REDUCTASE; POLLEN ANTIGEN; PROTEIN P30; PROTEIN P35; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; UNCLASSIFIED DRUG; VEGETABLE PROTEIN;

ALLERGIC REACTION; AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CATALYSIS; CHROMATOGRAPHY; CONTROLLED STUDY; CROSS REACTION; DEFENSE MECHANISM; ENZYME INHIBITION; ESCHERICHIA COLI; FOOD ALLERGY; FRUIT; HUMAN; IMMUNOBLOTTING; MEDIATOR RELEASE; NUCLEOTIDE SEQUENCE; PLANT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SEQUENCE HOMOLOGY; VEGETABLE;

NON-PROGRAMMATIC;

ALLERGENS; AMINO ACID SEQUENCE; BETULA; CLONING, MOLECULAR; CROSS REACTIONS; FOOD HYPERSENSITIVITY; FRUIT; HISTAMINE RELEASE; HUMANS; HYPERSENSITIVITY; IMMUNE SERA; IMMUNOBLOTTING; IMMUNOGLOBULIN E; MOLECULAR SEQUENCE DATA; NADP; OXIDOREDUCTASES; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; POLLEN; SEQUENCE HOMOLOGY, AMINO ACID; VEGETABLES;

EID: 0034791266     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0014-2956.2001.02463.x     Document Type: Article

References (35)

1. Food hypersensitivity in patients with birch pollen allergy
2. Association between pollen hypersensitivity and edible vegetable allergy: A review
3. Allergenic cross-reactivity, food allergy and pollen
4. The gene coding for the major birch pollen allergen Bet v I is highly homologous to a pea disease resistance response gene
5. Profilin is a cross-reactive allergen in pollen and vegetable foods
6. Identification of allergens in fruits and vegetables: IgE cross-reactivities with the important birch pollen allergens Bet v 1 and Bet v 2 (birch profilin)
7. Involvement of carbohydrate epitopes in the IgE response of celery-allergic patients
8. Core α1,3-fucose is a key part of the epitope recognized by antibodies reacting against plant N-linked oligosaccharides and is present in a wide variety of plant extracts
9. Cross-reactive carbohydrate determinants
10. Molecular cloning and characterization of a birch pollen minor allergen, Bet v 5, belonging to a family of isoflavone reductase-related proteins
11. IgE binding to a new cross-reactive structure: A 35 kDa protein in birch pollen, exotic fruit and other plant foods
12. Characterisation of a new IgE-binding 35-kDa protein from birch pollen with cross-reacting homologues in various plant foods
13. Evolution of plant defense mechanisms: Relationships of phenylcoumaran benzylic ether reductases to pinoresinol-lariciresinol and isoflavone reductases
14. Stereo-isomerism in plant disease resistance: Induction and isolation of the 7,2′-dihydroxy-4′5′methylenedioxyisoflavone oxyreductase, an enzyme introducing chirality during synthesis of isoflavonoid phytoalexins in pea (Pisum sativum L)
15. Phylogenetic links in plant defense systems: Lignans, isoflavonoids and their reductases
16. (+)-Pinoresinol/(-)-lariciresinol reductase from Forsythia intermedia: Protein puriiccation, cDNA cloning, heterologous expression and comparison to isoflavone reductase
17. Characterization of the 18-kDa apple allergen by two-dimensional immunoblotting and microsequencing
18. Pyr c 1, the major allergen from pear (Pyrus communis), is a new member of the Bet v 1 allergen family
19. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
20. Cleavage of structural proteins during the assembly of the head of bacterio-phage T4
21. Electroblotting of multiple gels: A simple apparatus without buffer tank for rapid transfer of proteins from polyacrylamide to nitrocellulose
22. Apple allergy: The IgE binding potency of apple strains is related to the occurrence of the 18-kDa allergen
23. A new and simple radioimmunoassay method for the determination of IgE
24. An automated continuous-flow system for the extraction and fluorometric analysis of histamine
25. Refinements in the automated histamine analysis system
26. Automated histamine analysis for in vitro allergy testing. I. A method utilizing allergen-induced histamine release from whole blood
27. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
28. The isoflavonoid phytoalexin pathway: From enzymes to genes to transcription factors
29. Multiple sequence alignment with hierarchical clustering
30. Plant allergens and pathogenesis-related proteins. What do they have in common?
31. X-ray and NMR structure of Bet v 1, the origin of birch pollen allergy
32. Isolation and characterisation of the 18-kDa major apple allergen and comparison with the major birch pollen allergen (Bet v I)
33. Molecular cloning, expression and characterisation of Pru a 1, the major cherry allergen
34. Recombinant allergens expressed in E. coli: Benefits and drawbacks in the diagnosis of food allergies