Small-angle neutron scattering reveals an oxygen-dependent conformational change of the immunogen keyhole limpet hemocyanin type 1 (KLH1)

European Biophysics Journal

Volumn 30, Issue 6, 2001, Pages 471-475

  Hartmann, H ^a   Bongers, A ^a   Decker, H ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Immunogen; Keyhole limpet hemocyanin; Oxygen dependent conformations; Small angle neutron scattering

Indexed keywords

ANTIGEN; KEYHOLE LIMPET HEMOCYANIN; OXYGEN;

ARTICLE; CONFORMATIONAL TRANSITION; GASTROPOD; MOLECULAR MODEL; NEUTRON SCATTERING; OXYGEN AFFINITY; OXYGENATION; PROTEIN CONFORMATION; PROTEIN QUATERNARY STRUCTURE;

ANIMALS; BIOPHYSICS; HEMOCYANIN; MOLLUSCA; NEUTRONS; OXYGEN; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, QUATERNARY; SCATTERING, RADIATION;

GASTROPODA; MEGATHURA CRENULATA; OXY;

EID: 0034778181     PISSN: 01757571     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002490100169     Document Type: Article

References (26)

1. Structures of Helix pomatia oxy-hemocyanin and deoxy-hemocyanin tubular polymers
2. Crystal structure of a functional unit from octopus hemocyanin
3. Small angle X-ray scattering reveals differences between the quaternary structures of oxygenated and deoxygenated tarantula hemocyanin
4. Quaternary structure, subunits and domain pattern of two discrete forms of keyhole limpet hemocyanin: KLH1 and KLH2
5. Keyhole limpet hemocyanin (KLH): A biomedical review
6. Keyhole limpet hemocyanin: Molecular structure of a potent marine immunoactivator. A review
7. Monte Carlo modeling of small-angle scattering data from non-interacting homogeneous and heterogeneous particles in solution
8. Hemocyanins
9. Hemocyanins and invertebrate evolution
10. Keyhole limpet hemocyanin for carcinoma in situ of the bladder: A long-term follow-up study
11. Keyhole limpet hemocyanin immunotherapy of bladder cancer: Laboratory and clinical studies
12. Structures of two molluscan hemocyanin genes: Significance for gene evolution
13. Quaternary structure, subunits and domain patterns of two discrete forms of keyhole limpet hemocyanin: KLH1 and KLH2
14. Molecular structure of arthropodan hemocyanins
15. Structure of a molluscan hemocyanin didecamer (HtH1 from Haliotis tuberculata) at 12 Å resolution by cryoelectron microscopy
16. Sequence of the octopus dofleini hemocyanin subunit: Structural and evolutionary implications
17. Structure of keyhole limpet hemocyanin type 1 (KLH1) at 15 Å resolution by electron cryomicroscopy and angular reconstitution
18. Studies by X-ray small-angle scattering of the quaternary structure in solution of halves and tenths of Helix pomatia haemocyanin and of Sepia officinalis haemocyanin
19. Hemocyanin molecular architecture: Structure and reactivity of the binuclear copper-active site
20. Hemocyanin levels in the giant keyhole limpet, Megathura crenulata, from the coast of California
21. Hemocyanin of the giant keyhole limpet Megathura crenulata
22. Mass determination, subunit organization and control of oligomerization states of keyhole limpet hemocyanin (KLH)
23. Structural changes of the Escherichia coli GroEL-GroES chaperonins upon complex formation in solution: A neutron small angle scattering study
24. Small-angle scattering data treatment by the regularization method
25. A model of the quaternary structure of the Escherichia coli F1 ATPase from X-ray solution scattering and evidence for structural changes in the delta subunit during ATP hydrolysis
26. Keyhole limpet hemocyanin: Structural and functional characterization of two different subunits and multimers