Conformation and other biophysical properties of cyclic antimicrobial peptides in aqueous solutions

Journal of Peptide Research

Volumn 58, Issue 4, 2001, Pages 293-306

  Jelokhani Niaraki, M ^a,b   Prenner, E J ^a   Kay, C M ^a   McElhaney, R N ^a   Hodges, R S ^c   Kondejewski, L H ^a,d  

^a UNIVERSITY OF ALBERTA   (Canada)

^b BRANDON UNIVERSITY   (Canada)

^c UNIVERSITY OF COLORADO   (United States)

^d Caprion Pharmaceuticals   (Canada)

Author keywords

Amphipathicity; Biological activity; Biophysical properties in aqueous solution; Cyclic antimicrobial peptides; Structure function relationship

Indexed keywords

[4 DEXTRO LYSINE] PEPTIDE GS14; GRAMICIDIN S; PEPTIDE GS10; PEPTIDE GS12; PEPTIDE GS14; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CONCENTRATION RESPONSE; CYCLIZATION; DRUG ACTIVITY; HYDROPHOBICITY; IONIC STRENGTH; MEMBRANE STRUCTURE; NONHUMAN; PEPTIDE ANALYSIS; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN CONFORMATION; STRUCTURE ACTIVITY RELATION; TEMPERATURE MEASUREMENT;

ANTI-BACTERIAL AGENTS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PEPTIDES, CYCLIC; POLYTETRAFLUOROETHYLENE; SODIUM FLUORIDE; SOLUTIONS; SURFACE PROPERTIES; TEMPERATURE; THERMODYNAMICS; WATER;

BACTERIA (MICROORGANISMS);

EID: 0034776345     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3011.2001.00893.x     Document Type: Article

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