Determinants of bone mineral density in older men and women: Body composition as mediator

Journal of Bone and Mineral Research

Volumn 16, Issue 11, 2001, Pages 2142-2151

  Pluijm, S M F ^a   Visser, M ^a   Smit, J H ^a   Popp Snijders, C ^a   Roos, J C ^a   Lips, P ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Aging; Appendicular muscle mass; Bone mineral density; Fat mass; Hormones; Lifestyle

Indexed keywords

PARATHYROID HORMONE; SEX HORMONE BINDING GLOBULIN;

AGED; AGING; ARTICLE; BODY COMPOSITION; BODY FAT; BODY WEIGHT; BONE DENSITY; BONE MINERAL; CHRONIC DISEASE; CONTROLLED STUDY; DRUG UTILIZATION; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; HIP; HORMONAL REGULATION; HUMAN; LIFESTYLE; MAJOR CLINICAL STUDY; MALE; MUSCLE MASS; NETHERLANDS; PARATHYROID HORMONE BLOOD LEVEL; PROTEIN BLOOD LEVEL; REGRESSION ANALYSIS; SEX DIFFERENCE; SMOKING; SPORT; WALKING;

ADIPOSE TISSUE; AGED; AGED, 80 AND OVER; AGING; BODY COMPOSITION; BODY WEIGHT; BONE DENSITY; FEMALE; HIP; HUMANS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; MUSCLE, SKELETAL; NETHERLANDS; SEX HORMONE-BINDING GLOBULIN; WALKING;

EID: 0034772909     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2001.16.11.2142     Document Type: Article

References (73)

1. Who are candidates for prevention and treatment for osteoporosis?
2. Genetic and environmental components of the population variance in bone density
3. Vitamin D3 and calcium to prevent hip fractures in elderly women
4. Effect of calcium and vitamin D supplementation on bone density in men and women 65 years of age or older
5. A prospective study of alcohol consumption and bone mineral density
6. Cigarette smoking and bone mineral density in older men and women
7. A meta-analysis of cigarette smoking, bone mineral density and risk of hip fracture: Recognition of a major effect
8. Weight-training effects on bone mineral density in early post-menopausal women
9. Effects of high-intensity strength training on multiple risk factors for osteoporotic fractures. A randomized controlled trial
10. Hormonal predictors of bone loss in elderly women: A prospective study
11. Association between insulin-like growth factor I and bone mineral density in older women and men: The Framingham Heart Study
12. Osteoporosis in rheumatoid arthritis
13. Steroid-induced osteoporosis
14. The effect of low-dose continuous estrogen and progesterone therapy with calcium and vitamin D on bone in elderly women. A randomized, controlled trial
15. Hemiosteoporosis after severe stroke, independent of changes in body composition and weight
16. Asthma and chronic obstructive airway diseases are associated with osteoporosis and fractures: A literature review
17. Bone mineral density in patients with type 1 and type 2 diabetes
18. To what extent is bone mass determined by fat-free or fat mass?
19. Associations of fat and muscle masses with bone mineral in elderly men and women
20. Muscle mass and fat mass in relation to bone mineral density in very old men and women: The Framingham Heart Study
21. Determinants of total body and regional bone mineral density in normal postmenopausal women-a key role for fat mass
22. Volumetric bone density of the lumbar spine is related to fat mass but not lean mass in normal postmenopausal women
23. Fat mass is an important determinant of whole body bone density in premenopausal women but not in men
24. Determinants of bone mineral density and risk factors for osteoporosis in healthy elderly women
25. Osteoporosis of the slender smoker. Vertebral compression fractures and loss of metacarpal cortex in relation to postmenopausal cigarette smoking and lack of obesity
26. Decreased axial bone mineral density in perimenopausal women with rheumatoid arthritis: A population based study
27. Osteoporosis in older adults with non-insulin dependent diabetes mellitus: Is it sex related?
28. Associations of body fat distribution, circulating sex hormones, and bone density in postmenopausal women
29. Genetic and environmental influences on total-body and central abdominal fat: The effect of physical activity in female twins
30. Predictors of lean body mass and total adipose mass in community-dwelling elderly men and women
31. Body fat distribution in relation to physical activity and smoking habits in 38-year-old European men. The European Fat Distribution Study
32. Physical activity is a significant predictor of body density in women
33. A multicenter study of the influence of fat and lean mass on bone mineral content: Evidence for differences in their relative influence at major fracture sites
34. Procedures and results of the field work
35. A physical activity questionnaire for the elderly
36. The prevalence of selected physical activities and their relation with coronary heart disease risk factors in elderly men: The Zutphen Study, 1985
37. Dual-energy x-ray absorptiometry for total-body and regional bone-mineral and soft-tissue composition
38. Dual-energy X-ray absorptiometry body composition model: Review of physical concepts
39. Regional skeletal muscle measurement: Evaluation of new dual-energy X-ray absorptiometry model
40. The moderator-mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations
41. Toward terminological, conceptual, and statistical clarity in the study of mediators and moderators: Examples from the child-clinical and pediatric psychology literatures
42. Consequences of childhood-onset growth hormon deficiency for adult bone mass
43. Differential changes in bone mineral density of the appendicular and axial skeleton with aging: Relationship to spinal osteoporosis
44. Lifestyle factors and bone density in the elderly: Implications for osteoporosis prevention
45. Determinants of bone loss in elderly men and women: A prospective population-based study
46. Determinants of bone loss from the femoral neck in women of different ages
47. Heterogeneity in osteoporosis. Men versus women
48. Effect of diet-induced weight loss on total body bone mass
49. Weight change and fractures in older women
50. Bone dimensional change with age: Interactions of genetic, hormonal, and body size variables
51. Bone loss accompanying voluntary weight loss in obese humans
52. Bone mineral density and long term exercise. An overview of cross-sectional athlete studies
53. Exercise: A prevention and treatment for osteoporosis and injurious falls in the older adult
54. Good maintenance of high-impact activity-induced bone gain by voluntary, unsupervised exercises: An 8-month follow-up of a randomized controlled trial
55. Risk factors for increased bone loss in an elderly population: The Rotterdam Study
56. Predictors of fractures in elderly women
57. Sex hormone binding globulin in postmenopausal women: A predictor of osteoporosis superior to endogenous oestrogens
58. Biochemical parameters associated with low bone density in healthy men and women
59. Importance of albumin, 25(OH)-vitamin D and IGFBP-3 as risk factors in elderly women and men with hip fracture
60. Relation between body size and bone mineral density in elderly men and women
61. Fat mass is an important determinant of whole body bone density in premenopausal women but not in men
62. Relation between bone mass and muscle weight
63. Aromatization by skeletal muscle
64. Conversion of androstenedione to estrone by human tissue
65. Source of estrogen production in postmenopausal women
66. Circulating insulin levels are related to bone density in normal postmenopausal women
67. Inhibition of sex hormone-binding globulin production in the human hepatoma (Hep G2) cell line by insulin and prolactin
68. Systemic administration of amylin increases bone mass, linear growth, and adiposity in adult male mice
69. Leptin inhibits bone formation through a hypothalamic relay: A central control of bone mass
70. Sex hormone binding globulin: Origin, function and clinical significance
71. Underweight and overweight in relation to mortality among men aged 40-59 and 50-69 years: The Seven Countries Study
72. Exercise and skeletal health