Yields of SSB and DSB induced in DNA by AlK ultrasoft X-rays and α-particles: Comparison of experimental and simulated yields

International Journal of Radiation Biology

Volumn 77, Issue 10, 2001, Pages 1053-1066

  Fulford, J ^a   Nikjoo, H ^a   Goodhead, D T ^a   O'Neill, P ^a  

^a MRC Radiation/Genome Stability Unit   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PLASMID DNA; PLUTONIUM 238;

ALPHA RADIATION; AQUEOUS SOLUTION; ARTICLE; COMPARATIVE STUDY; COMPUTER SIMULATION; CONTROLLED STUDY; DNA DAMAGE; GEL ELECTROPHORESIS; PRIORITY JOURNAL; RADIATION DOSE; SCAVENGING SYSTEM; SYSTEM ANALYSIS; X RAY;

ALPHA PARTICLES; DNA; DNA DAMAGE; DNA, SINGLE-STRANDED; HYDROXYL RADICAL; X-RAYS;

EID: 0034769696     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/09553000110069308     Document Type: Article

References (68)

1. Induction and rejoining of DNA double-strand breaks in Chinese Hamster V79-4 cells irradiated with characteristic Aluminium K and Copper L ultrasoft X-rays
2. Effect of radiation type in water radiolysis
3. Radioprotection by DMSO of mammalian cells exposed to X-rays and to heavy charged-particle beams
4. The deposition of energy in small cylindrical targets by high LET radiations
5. 125I
6. Calculation of initial yields of single- and double-strand breaks in cell nuclei from electrons, protons and alpha particles
7. Computer simulation of initial events in the biochemical mechanisms of DNA damage
8. Dependence of the yield of DNA double strand breaks in Chinese hamster V79-4 cells on photon energy of characteristic ultrasoft X-rays
9. The effect of dimethyl sulfoxide on the induction of DNA double-strand breaks in V79-4 mammalian cells by alpha particles
10. Anatomy of A-, B- and Z-DNA
11. Simulation of DNA fragment distributions after irradiation with photons
12. Monte Carlo simulations of the production of short DNA fragments by low-linear energy transfer radiation using higher-order DNA models
13. Experimental determination of the dependence of OH radical yield on photon energy: A comparison with theoretical simulations
14. Initial events in the cellular effects of ionising radiation: Clustered damage in DNA
15. A versatile plutonium-238 irradiator for radiobiological studies with α-particles
16. Track structure analysis of ultrasoft X-rays compared to high- and low-LET radiations
17. Inactivation and mutation of cultured mammalian cells by aluminium characteristic ultra-soft X-rays. 1. Properties of aluminium X-rays and preliminary experiments with Chinese hamster cells
18. Effectiveness of 0.3 keV carbon ultrasoft X-rays for the inactivation and mutation of cultured mammalian cells
19. Is selective absorption of ultrasoft x-rays biologically important in mammalian cells?
20. Single- and double-strand breaks in pBR322 DNA by vacuum-UV from 8.3 to 20.7 eV
21. Calculation of initial and primary yields in the radiolysis of water
22. Production and dosimetry of copper L ulrasoft x-rays for biological and biochemical investigations
23. Rejoining of γ-radiation induced single strand breaks in plasmid DNA by human cell extracts: Dependence on the concentration of the hydroxyl radical scavenger, Tris
24. Production of DNA strand breaks by direct effects of heavy charged particles
25. Dosimetry comparison and characterisation of an Al K ultrasoft x-ray beam from an MRC cold-cathode source
26. Direct comparison of biological effectiveness of protons and alpha-particles of the same LET
27. Induction and rejoining of DNA double-strand breaks in V79-4 mammalian cells following γ- and α-irradiation
28. The induction of DNA double strand breaks in V79-4 cells by γ and α radiations-complexity of damage
29. Effects of postirradiation temperature on the yields of radiation-induced single and double-strand breakage in SV40 DNA
30. 4He ions
31. Radiation chemical mechanisms of single- and double-strand break formation in irradiated SV40 DNA
32. Yields of OH in gamma-irradiated DNA as a function of DNA hydration: Hole transfer in competition with OH formation
33. Yields of hydroxyl radical and hydrated electron scavenging reactions in aqueous solutions of biological interest
34. Theory of the chemical effects of high-energy electrons
35. Model of DNA damage induced by radiation of different quality
36. Variation of single-strand yield with scavenger concentration for plasmid DNA irradiated in aqueous solution
37. Characterization of the reaction rate coefficient of DNA with the hydroxyl radical
38. Modelling DNA damage induced by different energy photons and tritium beta-particles
39. The cellular environment in computer simulations of radiation-induced damage to DNA
40. DNA double-strand break distribution in X-ray and α-particle irradiated V79 cells: Evidence for non-random breakage
41. Monte Carlo track structure studies of energy deposition and calculation of initial DSB and RBE
42. Energy deposition in small cylinder targets by monoenergetic electrons
43. Computational modelling of low-energy electron-induced DNA damage by early physical and chemical events
44. Modelling of radiation-induced DNA damage: The early physical and chemical event
45. Quantitative modelling of DNA damage using Monte Carlo track structure method
46. Computational approaches for determining the spectrum of DNA damage induced by ionising radiation
47. Track structure in radiation biology: Theory and applications
48. Radiation track structure theory
49. 238Pu α-particles
50. Evidence for induction of DNA double-strand breaks at paired radical sites
51. A study of endonuclease III-sensitive sites in irradiated DNA: Detection of α-particle-induced oxidative damage
52. Characterization of the hydroxyl radical-induced damage after sparsely and densely ionizing irradiation
53. Estimation of life times and diffusion distances of radicals involved in X-ray-induced strand breaks or killing of mammalian cells
54. Pulse radiolysis of aqueous solutions of deoxyribonucleotides and of DNA: Reaction with hydroxy-radicals
55. Stopping powers and ranges of protons, deuterons and alpha-particles in selected materials. Part 2. Deuterons, energy = 10 keV to 20 MeV
56. Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation
57. Simulation of space and time evolution of radiolytic species induced by electrons in water
58. Cross sections for 0.025 eV-1 keV electrons and 10 eV-1 keV photons
59. Monte Carlo simulation of physiochemical processes of liquid water radiolysis
60. Monte Carlo simulation of DNA strand-break induction in supercoiled plasmid pBR322 DNA from indirect effects
61. A knowledge-based model of DNA hydration
62. Radiation-induced strand breaks in ψX174 replicative form DNA: An improved experimental and theoretical approach
63. The complexity of DNA damage: Relevance to biological consequences
64. Oxidation yield of the ferrous ion in a Fricke solution irradiated with monochromatic synchrotron soft X-rays in the 1.8-10 keV region
65. A Monte Carlo code for positive ion track simulation
66. A spur diffusion model applied to estimate yields of species in water irradiated by monoenergetic photons of 50 eV-2 MeV