Effects of potassium channel and Na+-Ca2+ exchange blockers on the responses of slowly adapting pulmonary stretch receptors to hyperinflation in flecainide-treated rats

British Journal of Pharmacology

Volumn 134, Issue 3, 2001, Pages 682-690

  Matsumoto, S ^a   Nishikawa, T ^a   Yoshida, S ^a   Ikeda, M ^a   Tanimoto, T ^a   Saiki, C ^a   Takeda, M ^a  

^a NIPPON DENTAL UNIVERSITY   (Japan)

Author keywords

Hyperinflation; Slowly adapting pulmonary stretch receptor

Indexed keywords

2 [2 [4 (4 NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA METHANESULFONATE; 4 AMINOPYRIDINE; FLECAINIDE; INHIBITOR PROTEIN; POTASSIUM CHANNEL; SLOW ADAPTING RECEPTOR; TETRYLAMMONIUM; VERATRIDINE;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG RECEPTOR BINDING; LUNG INFLATION; LUNG RECEPTOR; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; SODIUM CALCIUM EXCHANGE; VAGOTOMY;

EID: 0034769434     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704277     Document Type: Article

References (39)

1. Antiarrhythmic. 2. Synthesis and antiarrhythmic activity of N-(piperidylalkyl) trifluoroethyoxybenzamides
2. Function and distribution of three types of rectifying channel in rat spinal root myelinated axons
3. Identification of vagal sensory receptors in the rat lung: Are there subtypes of slowly adapting receptors?
4. Tetrodotoxin-resistant impulses in single nociceptor nerve terminals in guinea-pig cornea
5. Voltage- and time-dependent depression of maximum rate of depolarization of guinea-pig ventricular action potential by two new antiarrhythmic drugs, flecainide and lorcainide
6. Alkaloid-modified sodium channels from lobster walking leg nerves in planar liquid bilayers
7. 4-Aminopyridine antagonizes saxitoxin- and tetrodotoxin-induced cardiorespiratory depression
8. --ATPase at a site different from ouabain and atrial peptides
9. Inward and delayed outward membrane currents in isolated neural somata under voltage-clamp
10. Polypeptides neurotoxins modify gating and apparent single-channel conductance of veratridine-activated channels in planar liquid bilayers
11. Characterization of the reverse Na/Ca exchange in squid axons and its modulation by Cai and ATP. Ca i-dependent Na i/Ca o and Na i/Na o exchange modes
12. Development of 4-AP and TEA sensitivities in mammalian myelinated nerve fibers
13. Cellular and molecular biology of voltage-gated sodium channels
14. Pharmacological sensitivities of two after hyperpolarizations in rat optic nerve
15. + Channels in the central nervous system
16. A quantitative description of membrane current and its application to conductance and excitation in nerve
17. Ionic selectivity of mechanically activated channels in spider neurons
18. Sodium-dependent receptor current in a new mechanoreceptor preparation
19. Functional differences between 4-aminopyridine and tetraethylammonium-sensitive potassium channels in myelinated axons
20. Hypoxic changes in hippocampal neurons
21. Effects of sodium and potassium channel blockers on hyperinflation-induced slowly adapting pulmonary stretch receptor stimulation in the rat
22. Flecainide blocks the stimulatory effect of veratridine on slowly adapting pulmonary stretch receptors in anaesthetized rabbits without changing lung mechanics
23. 2-induced slowly adapting pulmonary stretch receptor inhibition
24. Excitatory mechanism of veratridine on slowly adapting pulmonary stretch receptors in anesthetized rabbits
25. Potassium activation in Helix aspersa neurons under voltage clamp: A component mediated by calcium influx
26. 2+ exchange
27. Chemical as tools in the study of excitable membranes
28. Different voltage-dependent potassium conductances regulate action potential repolarization and excitability in frog myelinated axon
29. Heterogeneous distribution of fast and slow potassium channels in myelinated rat nerve fibers
30. Regulation of intracellular sodium in cultured rat hippocampal neurones
31. + current in hippocampal neurons
32. Role of extracelullar calcium in anoxic injury of mammalian central white matter
33. 2+ influx during anoxia in mammalian central nervous system white matter
34. 2+ exchanger
35. Characteristics of vagal afferent activity in rats: Three types of pulmonary receptors responding to collapse, inflation and deflation of the lung
36. 2+ exchange inhibitor, KB-R7943, on ouabain-induced arrhythemias in guinea-pigs
37. 2+ exchange current in guinea-pig cardiac ventricular cells
38. Interactions of amino-pyridines with potassium channels of squid axon membranes
39. Dynamics of amino-pyridine block of potassium channels in squid axon membranes