Effect of Na+/Ca2+ exchange inhibitor, KB-R7943 on ouabain-induced arrhythmias in guinea-pigs

British Journal of Pharmacology

Volumn 127, Issue 8, 1999, Pages 1846-1850

  Watano, Tomokazu ^a   Harada, Yoshimitsu ^b   Harada, Kengo ^b   Nishimura, Noriyasu ^b  

^a FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^b Pharmacol Group R/D Labs   (Japan)

Author keywords

Heart; KB R7943; Lidocaine; Na+ Ca2+ exchange (NCX); Ouabain induced arrhythmias; Positive tonotropic effect

Indexed keywords

(3 METHYLSULFONYL 4 PIPERIDINOBENZOYL)GUANIDINE METHANESULFONATE; 2 [2 [4 (4 NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA METHANESULFONATE; ANTIARRHYTHMIC AGENT; DILTIAZEM; LIDOCAINE; N [1 [4 (4 FLUOROPHENOXY)BUTYL] 4 PIPERIDINYL] N METHYL 2 BENZOTHIAZOLAMINE; OUABAIN; SODIUM CHANNEL BLOCKING AGENT; UNCLASSIFIED DRUG; 2 (2 (4 (4 NITROBENZYLOXY)PHENYL)ETHYL)ISOTHIOUREA METHANESULFONATE; 2-(2-(4-(4-NITROBENZYLOXY)PHENYL)ETHYL)ISOTHIOUREA METHANESULFONATE; CARDIOTONIC AGENT; DRUG DERIVATIVE; SODIUM CALCIUM EXCHANGE PROTEIN; THIOUREA; VASOCONSTRICTOR AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIARRHYTHMIC ACTIVITY; ARTERIAL PRESSURE; ARTICLE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ELECTROCARDIOGRAM; HEART ARREST; HEART ARRHYTHMIA; HEART ATRIUM ARRHYTHMIA; HEART ATRIUM CONTRACTION; HEART RATE; HEART VENTRICLE EXTRASYSTOLE; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; INOTROPISM; INTRAVENOUS DRUG ADMINISTRATION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; SODIUM CALCIUM EXCHANGE; SYSTOLIC TIME INTERVAL; ANIMAL; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; DRUG EFFECT; GUINEA PIG; HEART ATRIUM FUNCTION;

ANIMALS; ARRHYTHMIA; ATRIAL FUNCTION; CARDIOTONIC AGENTS; GUINEA PIGS; LIDOCAINE; MALE; OUABAIN; SODIUM-CALCIUM EXCHANGER; THIOUREA; VASOCONSTRICTOR AGENTS;

EID: 0032588144     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702740     Document Type: Article

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