Repression of XMyoD expression and myogenesis by Xhairy-1 in Xenopus early embryo

Mechanisms of Development

Volumn 109, Issue 1, 2001, Pages 61-68

  Umbhauer, Muriel ^a   Boucaut, Jean Claude ^a   Shi, De Li ^a  

^a Université René Descartes   (France)

Author keywords

Hairy; Mesoderm; Myf5; MyoD; Myogenesis; Myogenic factor; Notch signalling; Repressor; Xenopus

Indexed keywords

ACTIVIN; ALPHA ACTIN; CHORDIN; HELIX LOOP HELIX PROTEIN; MYOD PROTEIN; NOTCH RECEPTOR; VIRUS PROTEIN;

ARTICLE; BLASTULA; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ECTODERM; EMBRYO; FEMALE; GASTRULA; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE REPRESSION; GENETIC TRANSCRIPTION; INHIBITION KINETICS; MESODERM; MUSCLE DEVELOPMENT; NEURULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN SYNTHESIS; REPRESSOR GENE; SIGNAL TRANSDUCTION; SOMITE; TRUNK; XENOPUS;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BINDING SITES; DNA; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLYCOPROTEINS; GOOSECOID PROTEIN; HELIX-LOOP-HELIX MOTIFS; HOMEODOMAIN PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MESODERM; MUSCLE DEVELOPMENT; MUSCLE PROTEINS; MYOD PROTEIN; MYOGENIC REGULATORY FACTOR 5; MYOSIN LIGHT CHAINS; PROTEINS; REPRESSOR PROTEINS; T-BOX DOMAIN PROTEINS; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; XENOPUS LAEVIS; XENOPUS PROTEINS;

VERTEBRATA;

EID: 0034767387     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(01)00517-2     Document Type: Article

References (42)

1. Notch signaling: Cell fate control and signal integration in development
2. A dual requirement for neurogenic genes in Drosophila myogenesis
3. Lethal of scute, a proneural gene, participates in the specification of muscle progenitors during Drosophila embryogenesis
4. Notch1 is required for the coordinate segmentation of somites
5. A role for the Drosophila neurogenic genes in mesoderm differentiation
6. How is myogenesis initiated in the embryo?
7. Ectopic mesoderm induction in Xenopus embryos caused by widespread expression of a Brachyury homologue
8. Specificity for the Hairy/Enhancer of split basic Helix-Loop-Helix (bHLH) proteins maps outside the bHLH domain and suggest two separate modes of transcriptional repression
9. Delta 1-activated Notch inhibits muscle differentiation without affecting Myf5 and Pax3 expression in chick myogenesis
10. Role of frizzled 7 in the regulation of convergent extension movements during gastrulation in Xenopus laevis
11. Bmp-4 acts as a morphogen in dorsoventral mesoderm patterning in Xenopus
12. The function of hairy-related bHLH repressor proteins in cell fate decisions
13. Transient expression of XMyoD in non-somitic mesoderm of Xenopus gastrulae
14. In situ hybridization: An improved whole mount method for Xenopus embryos
15. Notch signalling acts in postmitotic avian myogenic cells to control MyoD activation
16. MyoD expression in the forming somites is an early response to mesoderm induction in Xenopus embryos
17. Xenopus Myf5 marks early muscle cells and can activate muscle genes ectopically in early embryo
18. The Notch ligand, X-Delta-2, mediates segmentation of the paraxial mesoderm in Xenopus embryos
19. Periodic repression of Notch pathway genes governs the segmentation of Xenopus embryos
20. Signalling downstream of activated mammalian Notch
21. Notch signalling and the synchronization of the somite segmentation clock
22. Notch signalling is required for cyclic expression of the hairy-like gene HES1 in the presomitic mesoderm
23. The intracellular domain of mouse Notch: A constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD
24. Signal transduction by activated mNotch: Importance of proteolytic processing and its regulation by the extracellular domain
25. Delta-induced Notch signaling mediated by RBP-J inhibits MyoD expression and myogenesis
26. The neurogenic suppressor of hairless DNA-binding protein mediates the transcriptional activation of the enhancer of split complex genes triggered by Notch signaling
27. Expression cloning of Siamois, a Xenopus homeobox gene expressed in dorsal-vegetal cells of blastula and able to induce a complete secondary axis
28. Jagged, a mammalian ligand that activates Notch1
29. Somitogenesis: Segmenting a vertebrate
30. Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts
31. An activated Notch suppresses neurogenesis and myogenesis but not gliogenesis in mammalian cells
32. Avian hairy gene expression identifies a molecular clock linked to vertebrate segmentation and somitogenesis
33. Ubiquitous MyoD transcription at the midblastula transition precedes induction-dependent expression in the presumptive mesoderm
34. Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split
35. Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway
36. Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction
37. Temporal restriction of MyoD induction and autocatalysis during Xenopus mesoderm formation
38. Redefining the genetic hierarchies controlling skeletal myogenesis: Pax-3 and Myf-5 act upstream of MyoD
39. Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to neural fate
40. The myoD gene family: Nodal point during specification of the muscle cell ligneage
41. MyoD stimulates Delta-1 transcription and triggers Notch signaling in the Xenopus gastrula