TNP-470 reduces collagen and macrophage accumulation in expanded polytetrafluoroethylene tube implants

Journal of Surgical Research

Volumn 101, Issue 1, 2001, Pages 99-103

  Bond, S J ^a   Klein, S A ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; FUMAGILLOL CHLOROACETYLCARBAMATE; HYDROXYPROLINE; POLITEF;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; MACROPHAGE MIGRATION INHIBITION; MALE; MICROVASCULARIZATION; MOUSE; NONHUMAN; POLITEF IMPLANT; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; SCAR FORMATION; TENSILE STRENGTH;

EID: 0034764192     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.2001.6259     Document Type: Article

References (22)

1. Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth
2. Suppression of tumor metastasis by angiogenesis inhibition
3. Analysis of experimental antiangiogenic therapy
4. Angiogenesis inhibitor TNP-470 inhibits murine cutaneous wound healing
5. Development of a new miniature method for the study of wound healing in human subjects
6. Examination of expanded polytetrafluoroethylene wound healing models
7. The determination of hydroxyproline in tissue and protein samples containing small proportions of the amino acid
8. Comparison of the polyvinyl alcohol sponge and expanded polytetrafluoroethylene subcutaneous implants as models to evaluate wound healing potential in human beings
9. TNP-470 (AGM-1470): Mechanisms of action early clinical development
10. Interaction of angiogenesis inhibitor TNP-470 with basic fibroblast growth factors receptors
11. Fibroblast growth factors: At the heart of angiogenesis
12. Accelerated wound repair, cell proliferation and collagen accumulation are produced by a cartilage-derived growth factor
13. Mechanisms of accelerated wound repair using epidermal growth factor and basic fibroblast growth factor
14. Recombinant basic fibroblast growth factor accelerates wound healing
15. Immune aspects of wound repair
16. Wound healing: The role of the macrophage and other immune cells
17. Basic FGF and TRGF-beta differentially modulate integrin expression of human microvascular endothelial cells
18. Basic fibroblast growth factor modulates integrin expression in microvascular endothelial cells
19. Molecular recognition of angiogenesis inhibitors fumagillin and ovalicin by methionine aminopeptidase 2
20. The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2
21. Effects of perioperative treatment with TNP-470 on the resistance of colonic anastomoses in rats
22. TNP-470 inhibits intraabdominal adhesion formation