Regulation of microglial cell function by ATP

Japanese Journal of Psychopharmacology

Volumn 21, Issue 3, 2001, Pages 89-93

  Honda, S ^a   Kohsaka, S ^a  

^a NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

Author keywords

ATP; Chemotaxis; Gi o coupled P2Y receptors; Microglia; P2X7

Indexed keywords

ADENOSINE TRIPHOSPHATE; INTERLEUKIN 1BETA; PLASMINOGEN; PURINE P2Y RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

CELL DEATH; CELL FUNCTION; CHEMOTAXIS; CONCENTRATION RESPONSE; CYTOKINE RELEASE; MICROGLIA; NERVOUS SYSTEM; NEUROMODULATION; NEUROTRANSMISSION; REGULATORY MECHANISM; SHORT SURVEY;

ADENOSINE TRIPHOSPHATE; ANIMALS; CHEMOTAXIS; MICROGLIA; RECEPTORS, PURINERGIC P2;

EID: 0034762408     PISSN: 13402544     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (30)

1. Receptor and ion channel nomenclature supplement, 10th ed
2. ATP-induced arachidonic acid release in cultured astrocytes is mediated by Gi protein coupled P2Y1 and P2Y2 receptors
3. Chemokines induce migration and changes in actin polymerization in adult rat brain microglia and a human fetal microglial cell line in vitro
4. Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides
5. 2+ wave propagation in dorsal spinal cord astrocytes
6. Mouse microglial cells express a plasma membrane pore gated by extracellular ATP
7. Purinergic modulation of Interleukin-1β release from microglial cells stimulated wih bacterial endotoxin
8. Extracellular ATP activates transcription factor NF-KB through the P2Z purinoreceptor by selectively targeting NF-KB p65 (RelA)
9. P2Z purinoceptor ligation induces activation of caspases with distinct roles in apoptotic and necrotic alterations of cell death
10. P2X7/P2Z purinoreceptor-mediated activation of transcription factor NFAT in microglial cells
11. Production and function of monocyte chemoattractant protein-1 and other β-chemokines in murine glial cells
12. Extracellular ATP triggers TNF-α release from rat microglia
13. Identification of the platepet ADP receptor targeted by antithrombotic drugs
14. Extracellular ATP or ADP induce chemotaxis of cultured microglia through Gi/o-coupled P2Y receptors
15. 2+ dependent plasminogen release from cultured microglia
16. 2+ release from InsP3. sensitive internal stores in mammalian oligodendrocytes
17. Microglia: A sensor for pathological events in the CNS
18. Plasminogen promotes the development of rat mesencephalic dopaminergic neurons in vitro
19. Microglia-derived elastase produces a low-molecular weight plasminogen that enhances neurite out-growth in rat neocortical explant cultures
20. Extracellular ATP induces stellation and increases glial fibrillary acidic protein content and DNA synthesis in primary astrocyte cultures
21. Trophic actions of extracellular nucleotides and nucleosides on glial and neuronal cells
22. Mitogenic signaling by ATP/P2Y purinergic receptors in astrocytes: Involvement of a calcium-independent protein kinase C, extracellular signal-regulated protein kinase pathway distinct from the phosphatidylinositol-specific phospholipase C/calcium pathway
23. Complement 5a controls motility of murine microglial cells in vitro via activation of an inhibitory G-protein and the rearrangement of the actin cytoskeleton
24. Epidermal growth factor is a motility factor for microglial cells in vitro: Evidence for EGF receptor expression
25. Kinetics and mechanism of ATP-dependent IL-1β release from microglial cells
26. Intercellular communication in spinal cord astrocytes: Fine tuning between gap junctions and P2 nucleotide receptors in calcium wave propagation
27. 7)
28. Brain macrophages: On the role of pericytes and perivascular cells
29. Chemotaxis by a CNS macrophage, the microglia