Tumorigenicity of the mixed spindle-epithelioid SP6.5 and epithelioid TP17 uveal melanoma cell lines is differentially related to α5β1 integrin expression

Investigative Ophthalmology and Visual Science

Volumn 42, Issue 12, 2001, Pages 3058-3065

  Beliveau A ^a   Berube M ^a   Carrier, P ^a   Mercier, C ^a   Guerin S L ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRONECTIN; INTEGRIN;

ARTICLE; CANCER CELL CULTURE; CARCINOGENICITY; CELL COUNT; CELL GROWTH; CELL PROLIFERATION; CELL STRUCTURE; CELL SURFACE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; EPITHELIOID CELL; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; MELANOMA CELL; NUDE MOUSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UVEA MELANOMA;

ANIMALS; ANTIBODIES, BLOCKING; CELL ADHESION; FEMALE; FIBRONECTINS; FLOW CYTOMETRY; GENE EXPRESSION; HUMANS; MELANOMA; MICE; MICE, NUDE; NEOPLASM PROTEINS; RECEPTORS, FIBRONECTIN; TRANSFECTION; TUMOR CELLS, CULTURED; UVEAL NEOPLASMS;

EID: 0034759592     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Pathology of ocular melanomas
2. The biology of haematogenous metastasis in human uveal malignant melanoma
3. Prognostic parameters in uveal melanoma: A review
4. Malignant melanocytic tumors of the eye: A study of histologic types in 111 cases
5. Prognostic features of uveal malignant melanoma
6. Modifications of Callender's classification of uveal melanoma at the Armed Forces Institute of Pathology
7. Integrin and signal transduction pathways: The road taken
8. Integrin signaling
9. Fibronectin and its integrin receptors in cancer
10. Changes in integrin receptors on oncogenically transformed cells
11. Modulatory roles for integrin activation and the synergy site of fibronectin during matrix assembly
12. Fibronectin fibrillogenesis: A paradigm for extracellular matrix assembly
13. Increased tumorigenicity of fibronectin receptor deficient Chinese hamster ovary cell variants
14. Integrin alpha 5 beta 1 expression negatively regulates cell growth: Reversal by attachment to fibronectin
15. Elevated levels of the alpha 5 beta 1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells
16. Role of α5β1 integrin in determining malignant properties of colon carcinomas cells
17. Disruption of epithelial cell-matrix interactions induces apoptosis
18. Inhibition of pp125FAK in cultured fibroblast results in apoptosis
19. Suppression of ICE, and apoptosis in mammary epithelial cells by extracellular matrix
20. Expression of integrin α5β1 and MMPs associated with epithelioid morphology and malignancy of uveal melanoma
21. Gangliosides in human uveal melanoma metastatic process
22. A new technology for assaying infectivity of human adenovirus 5 DNA
23. Characterization of anti-peptide antibodies directed towards the automodification domain and apoptotic fragment of poly (ADP-ribose) polymerase
24. Loss of the tumorigenic phenotype with in vitro, but not in vivo, passaging of a novel series of human bronchial epithelial cell lines: Possible role of an α5/β1-integrin-fibronectin interaction
25. Skin equivalent produced with human collagen
26. Influence of dermal equivalent maturation on the development of a cultured skin equivalent
27. Expression of the integrin α5 subunit in HT29 colon carcinoma cells suppresses apoptosis triggered by serum deprivation
28. The α5β1 integrin supports survival of cells on fibronectin and up-regulates bcl-2 expression
29. Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines
30. Coexpression of vimentin and keratins by human melanoma tumor cells: Correlation with invasive and metastatic potential
31. Intermediate filaments: Structure, dynamics, function, and disease
32. The intermediate filament cytoskeleton in tissues and cultured cells: Differentiation specificity of expression of cell architectural elements
33. Cell-type-specific markers in differentiation and pathology
34. Biologic determinants of uveal melanoma metastatic phenotype: A role of intermediate filaments as predictive markers
35. An immunohistochemical and prognostic analysis of cytokeratin expression in malignant uveal melanoma
36. Experimental coexpression of vimentin and keratin intermediate filaments in human melanoma cells augments motility
37. Role of intermediate filaments in migration, invasion and metastasis
38. Experimental coexpression of vimentin and keratin intermediate filaments in human breast cancer cells results in phenotypic interconversion and increased invasive behavior