Identification of KIN (KIN17), a human gene encoding a nuclear DNA-binding protein, as a novel component of the TP53-independent response to ionizing radiation

Radiation Research

Volumn 156, Issue 5 I, 2001, Pages 535-544

  Masson, C ^a   Menaa, F ^a   Pinon Lataillade, G ^a   Frobert, Y ^a   Radicella, J P ^a   Angulo, J F ^a  

^a Centre de Fontenay aux Roses   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; CESIUM 137; DNA BINDING PROTEIN; PROTEIN P53;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DNA DAMAGE; GAMMA IRRADIATION; GENOTOXICITY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IONIZING RADIATION; MELANOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR GENE;

BACTERIA (MICROORGANISMS);

EID: 0034758051     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/0033-7587(2001)156[0535:IOKKAH]2.0.CO;2     Document Type: Article

References (44)

1. Molecular cloning and characterisation of the human Kin17 cDNA encoding a component of the UVC-response that is conserved among metazoans
2. Identification of a mouse cDNA fragment whose expressed polypeptide reacts with anti-recA antibodies
3. KIN17, a mouse nuclear protein, binds to bent DNA fragments that are found at illegitimate recombination junctions in mammalian cells
4. Btcd, a mouse protein that binds to curved DNA, can substitute in Escherichia coil for H-NS, a bacterial nucleoid protein
5. The nuclear concentration of kin17, a mouse protein that binds to curved DNA, increases during cell proliferation and after UV irradiation
6. Enhanced expression of the kin17 protein immediately after low doses of ionizing radiation
7. UV-induced stabilization of fos and other short-lived mRNAs
8. Ectopic expression of (Mm)Kin17 protein inhibits cell proliferation of human tumor-derived cells
9. Overexpression of kin17 protein disrupts nuclear morphology and inhibits the growth of mammalian cells
10. Impairment of Fas-antigen expression in Adriamycin-resistant but not TNF-resistant MCF7 tumor cells
11. Ataxia-telangiectasia: Mutations in ATM cDNA detected by protein-truncation screening
12. Reverse transcription-polymerase chain reaction (RT-PCR) assays of estrogen and progesterone receptors in breast cancer
13. Inhibition of growth of human malignant glioblastoma in nude mice by antagonists of bombesin/gastrin-releasing peptide
14. DNA damage-related gene expression as biomarkers to assess cellular response after gamma irradiation of a human lymphoblastoid cell line
15. Overexpression of kin17 protein forms intranuclear foci in mammalian cells
16. Ultraviolet light-responsive element (TGACAACA)-binding proteins in cells of xeroderma pigmentosum patients
17. WAF1, a potential mediator of p53 tumor suppression
18. Cip1/Waf1 proteins following gamma-irradiation of human lymphoma cells
19. Resistance of MCF7 human breast carcinoma cells to TNF-induced cell death is associated with loss of p53 function
20. NBP is the p53 homolog p63
21. Role of the p53-homologue p73 in E2F1-induced apoptosis
22. ATF-2 contains a phosphorylation-dependent transcriptional activation domain
23. ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents
24. Expression of dominant negative CREB reduces resistance to radiation of human melanoma cells
25. ATF2 confers radiation resistance to human melanoma cells
26. Early response gene signalling cascades activated by ionising radiation in primary human B cells
27. Induction of transcription of "immediate early genes" by low-dose ionizing radiation
28. Fluorescent cDNA microarray hybridization reveals complexity and heterogeneity of cellular genotoxic stress responses
29. The complexity of radiation stress responses: Analysis by informatics and functional genomics approaches
30. Twenty years of p53 research: Structural and functional aspects of the p53 protein
31. Signal transduction and cellular radiation responses
32. KARP-1 is induced by DNA damage in a p53- and ataxia telangiectasia mutated-dependent fashion
33. Studies on mammalian mutants defective in rejoining double-strand breaks in DNA
34. Internalisation of the bleomycin molecules responsible for bleomycin toxicity: A receptor-mediated endocytosis mechanism
35. Bleomycin
36. PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes
37. Ionizing radiation and short wavelength UV activate NF-κB through two distinct mechanisms
38. Further characterisation of the p53 responsive element - Identification of new candidate genes for trans-activation by p53
39. Transcription factor ATF2 cooperates with v-Jun to promote growth factor-independent proliferation in vitro and tumor formation in vivo
40. Activation of the rat cyclin A promoter by ATF2 and Jun family members and its suppression by ATF4
41. Heterodimer formation of cJun and ATF-2 is responsible for induction of c-jun by the 243 amino acid adenovirus E1A protein
42. Tumor necrosis factor alpha gene regulation in activated T cells involves ATF-2/Jun and NFATp
43. Down-regulation of tumor necrosis factor alpha expression by activating transcription factor 2 increases UVC-induced apoptosis of late-stage melanoma cells