Combination of drugs elevating extracellular adenosine with granulocyte colony-stimulating factor promotes granulopoietic recovery in the murine bone marrow after 5-fluorouracil treatment

Physiological Research

Volumn 50, Issue 5, 2001, Pages 521-524

  Hofer, M ^a   Pospisil M ^a   Weiterova L ^a   Znojil, V ^b   Vacha J ^b   Hola J ^a   Vacek, A ^a   Pipalova I ^a  

^a INSTITUTE OF BIOPHYSICS   (Czech Republic)

^b MASARYK UNIVERSITY   (Czech Republic)

Author keywords

5 fluorouracil; Adenosine monophosphate; Dipyridamole; Extracellular adenosine; Granulocyte colony stimulating factor; Granulopoiesis

Indexed keywords

ADENOSINE; ADENOSINE PHOSPHATE; DIPYRIDAMOLE; FLUOROURACIL; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW; CONTROLLED STUDY; DRUG COST; EXTRACELLULAR SPACE; GRANULOCYTE; GRANULOPOIESIS; HEMATOPOIETIC STEM CELL; MACROPHAGE; MALE; MOUSE; NONHUMAN; STEM CELL;

ADENOSINE; ADENOSINE MONOPHOSPHATE; ANIMALS; BONE MARROW; BONE MARROW CELLS; DIPYRIDAMOLE; DRUG INTERACTIONS; EXTRACELLULAR SPACE; FLUOROURACIL; GRANULOCYTE COLONY-STIMULATING FACTOR; GRANULOCYTES; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HUMANS; MACROPHAGES; MALE; MICE; RECOMBINANT PROTEINS;

EID: 0034757814     PISSN: 08628408     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. P1 and P2 receptors in cell growth and differentiation
2. Purinergic signalling: Pathophysiological roles
3. Granulocyte colony-stimulating factor and drugs elevating extracellular adenosine act additively to enhance the hemopoietic spleen colony formation in irradiated mice
4. Myeloid cell kinetics in mice treated with recombinant interleukin-3, granulocyte colony-stimulating factor (CSF), or granulocyte-macrophage CSF in vivo
5. Human granulocyte colony-stimulating factor specifically binds to murine myeloblastic NSF-60 cells and activates their guanosine triphosphate binding proteins/adenylate cyclase system
6. Synergistic effects of granulocyte colony-stimulating factor and drugs elevating extracellular adenosine on neutrophil production in mice
7. Granulocyte colony-stimulating factor and drugs elevating extracellular adenosine synergize to enhance haematopoietic reconstitution in irradiated mice