Granulocyte colony-stimulating factor and drugs elevating extracellular adenosine synergize to enhance haematopoietic reconstitution in irradiated mice

European Journal of Haematology

Volumn 60, Issue 3, 1998, Pages 172-180

  Pospisil M ^a   Hofer, M ^a   Znojil, V ^b   Netikova J ^a   Vacha J ^b   Hola J ^a   Vacek, A ^a  

^a INSTITUTE OF MATHEMATICS   (Czech Republic)

^b MASARYK UNIVERSITY   (Czech Republic)

Author keywords

Adenosine monophosphate; Dipyridamole; G CSF; Myelosuppression; Radiation; Therapy

Indexed keywords

ADENOSINE; ADENOSINE PHOSPHATE; COBALT 60; DIPYRIDAMOLE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLONY FORMING UNIT GM; CONTROLLED STUDY; DRUG POTENTIATION; ERYTHROID CELL; GAMMA IRRADIATION; GRANULOPOIESIS; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; MALE; MEGAKARYOPOIESIS; MONOCYTE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0031894651     PISSN: 09024441     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0609.1998.tb01019.x     Document Type: Article

References (43)

1. OGAWA M. Differentiation and proliferation of hematopoietic stem cells. Blood 1993: 81: 2844-2853.
2. METCALF D. Hematopoictic regulators: redundancy or subtlety? Blood 1993: 82: 3515-3523.
3. LOWRY PA. Hematopoietic stem cell cytokine response. J Cell Biochem 1995: 58: 410-415.
4. BRENNAN JK, LICHTMAN MA, DIPERSIO JF, ABBOUD CN. Chemical mediators of granulopoiesis: a review. Exp Hematol 1980: 8: 441-464.
5. IKEBUCHI K, CLARK SC, IHLE JN, SOUZA LM, OGAWA M. Granulocyte colony-stimulating factor enhances interleukin 3-dependent proliferation of multipotential hemopoietic progenitors. Proc Natl Acad Sci USA 1988: 85: 3445-3449.
6. MOLINEUX G, MIGDALSKA A, SZMITKOWSKI M, ZSEBO KM, DEXTER TM. Effects on hematopoiesis of recombinant stem cell factor (ligand for c-kit) administered in vivo to mice either alone or in combination with granulocyte colony-stimulating factor. Blood 1991: 78: 961-966.
7. PATCIIEN ML, FISCHER R, MACVITTIE TJ. Effects of combined administration of interleukin-6 and granulocyte colony-stimulating factor on recovery from radiation-induced hemopoietic aplasia. Exp Hematol 1993: 21: 338-344.
8. HEYWORTH CM, DEXTER TM, NICHOLLS SE, WHETTON AD. Combinations of colony-stimulating factors promote enhanced proliferative potential in enriched granulocyte-macrophage colony-forming cells. Exp Hematol 1994: 22: 1089-1094.
9. GROSSMANN A, LENOX J, DEISHER TA, et al. Synergistic effects of thrombopoietin and granulocyte colony-stimulating factor on neutrophil recovery in myelosuppressed mice. Blood 1996: 88: 3363-3370.
10. POSPÍŠIL M, HOFER M, ZNOJIL V, VÁCHA J, NETÍKOVÁ J, HOLÁ J. Synergistic effect of granulocyte colony-stimulating factor and drugs elevating extracellular adenosine on neutrophil production in mice. Blood 1995: 86: 3692-3697.
11. DALY JW. Adenosine receptors: targets for future drugs. J Med Chem 1982: 25: 197-207.
12. NEWBY AC. Adenosine and the concept of "retaliatory metabolites". Trends Biochem Sci 1984: 9: 42-44.
13. STILES GL. Adenosine receptors and beyond: molecular mechanisms of physiological regulation. Clin Res 1990: 38: 10-18.
14. BURNSTOCK G. Physiological and pathological roles of purines: an update. Drug Devel Res 1993: 28: 195-206.
15. RATHBONE MP, MIDDLEMISS PJ. GYSBERS JW, DEFORGE S, COSTELLO P, DEL MAESTRO RF. Purine nucleosides and nucleotides stimulate proliferation of a wide range of cell types. In Vitro Cell Dev Biol 1992: 28A: 529-536.
16. RATHBONE MP, CHRISTJANSON L, DEFORGE S, et al. Extracellular purine nucleosides stimulate cell division and morphogenesis: pathological and physiological implications. Med Hypotheses 1992: 37: 232-240.
17. 2 receptor on human neutrophils. J Immunol 1985: 135: 1366-1371.
18. GUALTIERI RJ, BERNE; RM, MCGRATH HE, HUSTER WJ, QUESENBERRY PJ. Effect of adenine nucleotides on granulopoiesis and lithium-induced granulocytosis in long-term bone marrow cultures. Exp Hematol 1986: 14: 689-695.
19. PLAGEMANN PGW, WOHLHUETER RM, WOFFENDIN C. Nucleoside and nucleobase transport in animal cells. Biochim Biophys Acta 1988: 947: 405-443.
20. GORDON EL, PEARSON JD, DICKINSON ES, MOREAU D, SLAKEY LL.The hydrolysis of extracellular adenine nucleotides by arterial smooth muscle cells. J Biol Chem 1989: 264: 18986-18992.
21. HARMENBERG J, HÖGLUND M, HELLSTRÖM-LINDBERG E. G-and GM-CFC in oncology and oncological haematology. Eur J Haematol 1994: 52: 1-28.
22. KILLMANN SA. Radiation effects on the myelocytic cell renewal system. In: Manual on Radiation Haematology. Technical Reports Series No 123, Vienna: International Atomic Energy Agency, 1971: 89-97.
23. LORD BI, MOLINEUX G, POJDA Z, SOUZA LM, MERMOD JJ, DEXTER TM. Myeloid cell kinetics in mice treated with recombinant interleukin-3, granulocyte colony-stimulating factor (CSF), or granulocyte-macrophage CSF in vivo. Blood 1991: 77: 2154-2159.
24. UCHIDA T, YAMAGIWA A. Kinetics of rG-CSF-induced neutrophilia in mice. Exp Hematol 1992: 20: 152-155.
25. TANIKAWA S, NAKAO I, TSUNEOKA K, NARA N. Effects of recombinant granulocyte colony-stimulating factor (rG-CSF) and recombinant granulocyte-macrophage colony-stimulating factor (rGM-CSF) on acute radiation hematopoietic injury in mice. Exp Hematol 1989: 17: 883-888.
26. PATCHEN ML, MACVITTIE TJ, SOLBERG BD, SOUZA LM. Therapeutic administration of recombinant human granulocyle colony-stimulating factor accelerates hemopoietic regeneration and enhances survival in a murine model of radiation-induced myelosuppression. Int J Cell Cloning 1990: 8: 107-122.
27. BROXMEYER HE, WILLIAMS DE, COOPER S, HANGOC G, RALPH P. Recombinant human granulocyte-colony stimulating factor and recombinant human macrophage-colony stimulating factor synergize in vivo to enhance proliferation of granulocyte-macrophage, crythroid, and multipotential progenitor cells in mice. J Cell Biochem 1988: 38: 127-136.
28. DE HAAN G, DONTJE B, ENGEL C, LOEFFLER M, NIJHOF W. The kinetics of murine hematopoietic stem cells in vivo in response to prolonged increased mature blood cell production induced by granulocyte colony-stimulating factor. Blood 1995: 86: 2986-2992.
29. POSPÍŠIL M, HOFER M, NETÍKOVÁ J, et al. Elevation of extracellular adenosine induces radioprotective effects in mice. Radial Res 1993: 134: 323-330.
30. POSPÍŠIL M, HOEFR M, ZNOJIL V, VÁCHA J, NETÍKOVÁ J, HOLÁ J. Radioprotection of mouse hemopoiesis by dipyridamole and adenosine monophosphate in fractionated treatment. Radiat Res 1995: 142: 16-22.
31. POJDA Z, MOLINEUX G, DEXTER TM. Hemopoietic effects of short-term in vivo treatment of mice with various doses of rhG-CSF. Exp Hematol 1990: 18: 27-31.
32. TAMURA M, HATTORI K, NOMURA H, et al. Induction of neutrophilic granulocytosis in mice by administration of purified human native granulocyte colony-stimulating factor (G-CSF). Biochem Biophys Res Commun 1987: 142: 454-460.
33. GILMORE GL, DEPASQUALE DK, FISCHER BC, SHADDUCK RK. Enhancement of monocytopoiesis by granulocyte colony-stimulating factor: evidence for secondary cytokine effects in vivo. Exp Hematol 1995: 23: 1319-1323.
34. ROZENGURT E. Early signals in the mitogenic response. Science 1986: 234: 161-166.
35. NAGASHIMA K, KARASAWA A. Modulation of erythropoietin production by selective adenosine agonists and antagonists in normal and anemic rats. Life Sci 1996: 59: 761-771.
36. BOUMA MG, STAD RK, VAN DEN WILDENBERG FAJM, BUURMAN WA. Differential regulatory effects of adenosine on cytokine release by activated human monocytes. J Immunol 1994: 153: 4159-4167.
37. RITCHIE PK, SPANGELO BL, KRZYMOWSKI DK, ROSSITER TB, KURTH E, JUDD AM. Adenosine increases interlcukin 6 release and decreases tumour necrosis factor release from rat adrenal zona glomerulosa cells, ovarian cells, anterior pituitary cells, and peritoneal macrophages. Cytokine 1997: 9: 187-198.
38. WILLIAMS GT, SMITH CA, SPOONCER E, DEXTER TM, TAYLOR DR. Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis. Nature 1990: 343: 76-79.
39. DE HAAN G, DONTJE B, NIJHOF W. Concepts of hemopoietic cell amplification. Synergy, redundancy and pleiotropy of cytokines affecting the regulation of erythropoiesis. Leuk Lymph 1996: 22: 385-394.
40. HOŠEK B, BOHÁČEK J, S̀IKULOVÁ J, POSPÍŠIL. M, VACEK A. Protection of early cellular damage in 1 Gy-irradiatcd mice by the elevation of extracellular adenosine. Radiat Environ Biophys 1992: 31: 289-297.
41. BOHÁČEK K J, HOŠEK B. POSPÍŠIL. M. Post-irradiation administration of adenosine monophosphate combined with dipyridamole reduces early cellular damage in mice. Life Sci 1993: 53: 1317-1324.
42. 4A and adenosine triphosphate interact with granulocyte-macrophage colony-stimulating factor to delay neutrophil apoptosis: implications for neutrophil : platelet interactions during inflammation. Blood 1996: 87: 3442-3449.
43. BROXMEYER HE, BENNINGER L, PATEL SR, BENJAMIN RS, VADHAN-RAJ S. Kinetic response of human marrow myeloid progenitor cells to in vivo treatment of patients with granulocyte colony-stimulating factor is different from the response to treatment with granulocyte-macrophage colony-stimulating factor. Exp Hemalol 1994: 22: 100-102.