Substitution mode of the amide fragment in some new N-[ω-[4-(2-methoxyphenyl)piperazin-1-yl]alkyl pyrid-2(1H)-ones and their 5-HT1A/5-HT2A activity

Polish Journal of Pharmacology

Volumn 53, Issue 4, 2001, Pages 369-376

  Paluchowska, M H ^a   Bugno, R ^a   Charakchieva Minol, S ^a   Bojarski, A J ^a   Wesolowska, A ^a  

^a INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

5 HT1A receptor antagonists; 5HT2A 5 HT1A selectivity; Pyrid 2(1H) one derivatives

Indexed keywords

AROMATIC AMIDE; LIGAND; N [OMEGA [4 (2 METHOXYPHENYL)PIPERAZIN 1 YL]ALKYL]PYRID 2 (1H) ONE DERIVATIVE; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR; SEROTONIN 2A RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; BRAIN CORTEX; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CONFORMATION; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; RAT; RAT STRAIN; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

ADRENERGIC UPTAKE INHIBITORS; ANIMALS; BEHAVIOR, ANIMAL; BODY TEMPERATURE; CEREBRAL CORTEX; CHROMATOGRAPHY, THIN LAYER; HIPPOCAMPUS; LIGANDS; LIP; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICE; PYRIDONES; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; RESERPINE; SEROTONIN ANTAGONISTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034748186     PISSN: 12306002     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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