Allosteric modulation of [3H]-CGP39653 binding through the glycine site of the NMDA receptor: Further studies in rat and human brain

British Journal of Pharmacology

Volumn 132, Issue 8, 2001, Pages 1883-1897

  Mugnaini, Manolo ^a,b   Meoni, Paolo ^b   Bunnemann, Bernd ^a   Corsi, Mauro ^a   Bowery, Norman G ^b  

^a GSK   (Italy)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Allosteric modulation; Autoradiography; CGP39653; Glutamate; Glycine; GV150526A; Human brain; NMDA receptor; Receptor binding

Indexed keywords

2 AMINO 4 PHOSPHONOMETHYL 3 HEPTENOIC ACID; GAVESTINEL; GLUTAMIC ACID; GLYCINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; 2 AMINO 5 PHOSPHONOVALERIC ACID; AMINO ACID RECEPTOR BLOCKING AGENT; DRUG DERIVATIVE; GLYCINE RECEPTOR; INDOLE DERIVATIVE;

ALLOSTERISM; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BRAIN CORTEX; CINGULATE GYRUS; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG BINDING SITE; DRUG RECEPTOR BINDING; FEMALE; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; INSULA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; AGED; ANIMAL; BRAIN LEVEL; DRUG EFFECT; IN VITRO STUDY; METABOLISM; SPRAGUE DAWLEY RAT; STIMULATION; SYNAPTIC MEMBRANE;

2-AMINO-5-PHOSPHONOVALERATE; AGED; ANIMALS; AUTORADIOGRAPHY; BRAIN CHEMISTRY; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; GLYCINE; HUMANS; INDOLES; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GLYCINE; RECEPTORS, N-METHYL-D-ASPARTATE; STIMULATION, CHEMICAL; SYNAPTIC MEMBRANES;

EID: 0034744496     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704017     Document Type: Article

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