Antimineralocorticoid 11β-substituted spirolactones exhibit androgen receptor agonistic activity: A structure function study

Molecular Pharmacology

Volumn 59, Issue 5, 2001, Pages 1307-1313

  Nirdé, Philippe ^a   Térouanne, Béatrice ^a   Gallais, Nadine ^a   Sultan, Charles ^a,b,c   Auzou, Gilles ^a  

^a INSERM   (France)

^b LAPEYRONIE HOSPITAL   (France)

^c HÔPITAL ARNAUD DE VILLENEUVE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; CYPROTERONE ACETATE; HYDROXYFLUTAMIDE; METRIBOLONE; MINERALOCORTICOID ANTAGONIST; SPIRONOLACTONE; ALDOSTERONE ANTAGONIST; LIGAND; STEROID;

AGONIST; ANIMAL CELL; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG STABILITY; HUMAN; HUMAN CELL; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; AMINO ACID SUBSTITUTION; ANIMAL; CELL CULTURE; CHEMISTRY; DRUG POTENTIATION; GENETIC TRANSFECTION; GENETICS; HAPLORHINI; METABOLISM; MUTATION; TRANSACTIVATION;

ALDOSTERONE ANTAGONISTS; AMINO ACID SUBSTITUTION; ANIMALS; CELLS, CULTURED; HAPLORHINI; LIGANDS; MUTATION; RECEPTORS, ANDROGEN; SPIRONOLACTONE; STEROIDS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANS-ACTIVATION (GENETICS); TRANSFECTION;

EID: 0034744368     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.59.5.1307     Document Type: Article

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