A single amino acid mutation of Ala-773 in the mineralocorticoid receptor confers agonist properties to 11β-substituted spirolactones

Molecular Pharmacology

Volumn 58, Issue 4, 2000, Pages 684-691

  Auzou, Gilles ^a   Fagart, Jérôme ^b   Souque, Anny ^a   Hellal Lévy, Chantal ^a   Wurtz, Jean Marie ^b   Moras, Dino ^b   Rafestin Oblin, Marie Edith ^a  

^a INSERM   (France)

^b INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

7ALPHA PROPYLSPIRONOLACTONE; ALANINE; ALDOSTERONE; GLUCOCORTICOID RECEPTOR; MIFEPRISTONE; MINERALOCORTICOID RECEPTOR; SPIRONOLACTONE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; STEROID BINDING;

EID: 0033798154     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.58.4.684     Document Type: Article

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