The native metastable fold of C1-inhibitor is stabilized by disulfide bonds

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1481, Issue 1, 2000, Pages 97-102

  Simonovic, Ivana ^a   Patston, Philip A ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

C1 inhibitor; Complement; Disulfide bond; Metastable state; Polymerization; Serpin

Indexed keywords

COMPLEMENT COMPONENT C1; SERINE PROTEINASE INHIBITOR;

ARTICLE; COMPLEMENT SYSTEM; DISULFIDE BOND; ENZYME INHIBITION; GLYCOSYLATION; HUMAN; KINETICS; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEINASE INHIBITION;

ALPHA 1-ANTITRYPSIN; BINDING SITES; COMPLEMENT C1 INACTIVATOR PROTEINS; COMPLEMENT C1 INHIBITOR PROTEIN; CYSTEINE; CYSTEINE PROTEINASE INHIBITORS; DISULFIDES; DITHIOTHREITOL; HEAT; HUMANS; OXIDATION-REDUCTION; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; UREA;

EID: 0034739282     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4838(00)00115-1     Document Type: Article

References (32)

1. Bock S.C., Skriver K., Nielsen E., Thøgerson H.C., Wiman B., Donaldson V.H., Eddy R.L., Marrinan J., Radziejewska E., Huber R., Shows T.B., Magnusson S. Biochemistry. 25:1986;4292-4301.
2. Davis A.E. III. Annu. Rev. Immunol. 6:1988;595-628.
3. Patston P.A., Hauert J., Michaud M., Schapira M. FEBS Lett. 368:1995;401-404.
4. Lennick M., Brew S.A., Ingham K.C. Biochemistry. 24:1985;2561-2568.
5. Creighton T.E. Nature. 356:1992;194-195.
6. Baker D., Agard D.A. Biochemistry. 33:1994;7505-7509.
7. Patston P.A., Gettins P.G.W. FEBS Lett. 373:1996;87-92.
8. Coutinho M., Aulak K.S., Davis A.E. III. J. Immunol. 153:1994;3648-3654.
9. Huber R., Carrell R.W. Biochemistry. 28:1989;8951-8966.
10. Odermatt E., Berger H., Sano Y. FEBS Lett. 131:1981;283-285.
11. Perkins S.J., Smith K.F., Amatayakul S., Ashford D., Rademacher T.W., Dwek R.A., Lachmann P.J., Harrison R.A. J. Mol. Biol. 214:1990;751-763.
12. Perkins S.J. FEBS Lett. 271:1990;89-92.
13. Schumaker V.N., Hanson D.C., Kilchherr E., Phillips M.L., Poon P.H. Mol. Immunol. 23:1986;557-565.
14. Nilsson T., Wiman B. Biochim. Biophys. Acta. 705:1982;271-276.
15. Nilsson T., Sjöholm I., Wiman B. Biochem. J. 213:1983;617-624.
16. de Agostini A., Schapira M., Wachtfogel Y.T., Colman R.W., Carrel S. Proc. Natl. Acad. Sci. USA. 82:1985;5190-5193.
17. D.P. Goldenberg, in: T.E. Creighton (Ed.), Protein Structure: A Practical Approach, IRL Press, 1989, pp. 225-250.
18. Huntington J.A., Olson S.T., Fan B., Gettins P.G.W. Biochemistry. 35:1996;8459-8503.
19. Lei J., Abrahams J.-P., Skinner R., Petitou M., Pike R.N., Carrell R.W. Proc. Natl. Acad. Sci. USA. 94:1997;14683-14688.
20. Elliott P.R., Abrahams J.-P., Lomas D.A. J. Mol. Biol. 275:1998;419-425.
21. Björquist P., Ehnebom J., Inghardt T., Hansson L., Lindberg M., Linschoten M., Strömqvist M., Deinum J. Biochemistry. 37:1998;1227-1234.
22. Davis A.E. III, Bissler J.J., Cicardi M. Behring Inst. Mitt. 93:1993;313-320.
23. Kirkegaard T., Jensen S., Schousboe S.L., Petersen H.H., Egelund R., Andreasen P.A., Rodenburg K.W. Eur. J. Biochem. 263:1999;577-586.
24. James E., Bottomley S.P. Arch. Biochem. Biophys. 356:1998;296-300.
25. James E., Whisstock J.C., Gore M.G., Bottomley S.P. J. Biol. Chem. 274:1999;9482-9488.
26. Dafforn T.R., Mahadeva R., Elliott P.R., Sivasothy P., Lomas D.A. J. Biol. Chem. 274:1999;9458-9555.
27. Gooptu B., Hazes B., Chang W.-S.W., Dafforn T.R., Carrell R.W., Read R.J., Lomas D.A. Proc. Natl. Acad. Sci. USA. 97:2000;67-72.
28. Christensen S., Valnickova Z., Thørgersen I.B., Olsen E.H.N., Enghild J.J. Biochem. J. 323:1997;847-852.
29. Longas M.O., Ferguson W.S., Finlay T.H. J. Biol. Chem. 255:1980;3436-3441.
30. Sun X.-J., Chang J.-Y. J. Biol. Chem. 264:1989;11288-11293.
31. Einarsson R., Jahr E., Stiber E., Engman L., Lundstrom H., Andersson L.O. Biochim. Biophys. Acta. 624:1980;386-396.
32. Travis J., Salvesen G.S. Annu. Rev. Biochem. 52:1983;655-709.