Synthesis, crystal structure, spectral properties and cytotoxic activity of platinum(II) complexes of 2-acetyl pyridine and pyridine-2-carbaldehyde N(4)-ethyl-thiosemicarbazones

Journal of Inorganic Biochemistry

Volumn 78, Issue 4, 2000, Pages 347-354

  Kovala Demertzi, Dimitra ^a   Yadav, Paras Nath ^a   Demertzis, Mavroudis A ^a   Coluccia, Mauro ^b  

^a UNIVERSITY OF IOANNINA   (Greece)

^b UNIVERSITY OF BARI   (Italy)

Author keywords

Crystal structure; Cytotoxic activity; Platinum(II) complexes; Spectroscopic studies; Thiosemicarbazonato complexes

Indexed keywords

CISPLATIN; PLATINUM COMPLEX; THIOSEMICARBAZONE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOTOXICITY; DRUG RESISTANCE; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OVARY CANCER; SPECTROSCOPY; ULTRAVIOLET SPECTROSCOPY;

CELL DIVISION; CELL SURVIVAL; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROGEN BONDING; INHIBITORY CONCENTRATION 50; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MODELS, MOLECULAR; SPECTROPHOTOMETRY, INFRARED; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; THIOSEMICARBAZONES; TUMOR CELLS, CULTURED;

EID: 0034737655     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0162-0134(00)00063-5     Document Type: Article

References (43)

1. Scovill J.P., Klayman D.L., Franchino C.F. J. Med. Chem. 25:1982;1261.
2. Agrawal K.C., Sartorelli A.C. Prog. Med. Chem. 15:1978;321.
3. Sartorelli A.C., Agrawal K.C., Tsiftsoglou A.S., Moore E.C. Adv. Enzyme Regul. 15:1977;117.
4. Schenley Ind., US Patent No. 2 719 161 (1952).
5. Bymes R.W., Mohan M., Antholine W.E., Xu R.X., Petering D.H. Biochemistry. 29:1990;7046.
6. M.C Miller III, C.N.Stineman, J.R. Vance, D.X. West, I.H. Hall, Anticancer Res. 18 (1998) 6A, 4131.
7. A. Mignot, M. Miocque, P. Binet, J.-R. Rapin, P. Rinjard, Eur. J. Med. Chim. Ther. 15 (1980) 1, 33.
8. R.H. Dodd, C. Ouannes, M. Robert-Gero, P. Potier, J. Med. Chem. 32 (1989) 6, 1272.
9. Kraker A., Krezoski S., Schneider J., Mingel D., Petering D.H. J. Biol. Chem. 260:1985;13710.
10. Quiroga A.G., Pérez J.M., López-Solera I., Masaquer J.R., Luque A., Román P., Edwards A., Alonso C., Navarro-Ranninger C. J. Med. Chem. 41:1998;1399.
11. Matesanz A.I., Perez J.M., Navarro P., Moreno J.M., Colacio E., Souza P. J. Inorg. Biochem. 76:1999;29-37.
12. Pérez J.M., Quiroga A.G., Montero E.I., Alonso C., Navarro-Ranninger C. J. Inorg. Biochem. 73:1999;235.
13. Papageorgiou A., Iakovidou Z., Mourelatos D., Mioglou E., Boutis L., Kotsis A., Kovala-Demertzi D., Domopoulou A., West D.X., Demertzis M.A. Anticancer Res. 17:1997;247.
14. Kovala-Demertzi D., Domopoulou A., Demertzis M.A., Valle G., Papageorgiou A. J. Inorg. Biochem. 68:1997;147.
15. D. Kovala-Demertzi, A. Domopoulou, M.A. Demertzis, A. Papageorgiou, D.X. West, Polyhedron 16 (1997) 20, 3625.
16. Kovala-Demertzi D., Demertzis M.A., Varagi V., Papageorgiou A., Mourelatos D., Mioglou E., Iakovidou Z., Kotsis A. Chemotherapy. 44:1998;421.
17. Kovala-Demertzi D., Miller J.R., Kourkoumelis N., Hadjikakou S.K., Demertzis M.A. Polyhedron. 18:1999;1005.
18. Kovala-Demertzi D., Domopoulou A., Demetrzis M.A., Raptopoulou C.P., Terzis A. Polyhedron. 13:1994;1917.
19. Kovala-Demertzi D., Domopoulou A., Demetrzis M.A., Valdés-Martínez J., Hernández-Ortega S., Espinosa-Pérez G., West D.X., Salberg M.M., Bain G.A., Bloom P.D. Polyhedron. 15:1996;2587.
20. D. Kovala-Demertzi, N. Kourkoumelis, D.X. West, J. Valdés-Martínez, S. Hernández-Ortega, Eur. J. Inorg. Chem. (1998) 861.
21. D. Kovala-Demertzi, M.A. Demertzis, A. Castineiras, D.X. West, Polyhedron 17 (1998) 21, 3739.
22. D.D. Perrin, W.L.F. Armarego, D.R. Perrin, Purification of Laboratory Chemicals, 2nd ed., Pergamon, Oxford, 1980.
23. Hemmerich P., Prijs B., Erlenmeyer H. Helv. Chim. Acta. 217:1958;2059.
24. Kovala-Demertzi D., Tsangaris J.M., Hadjiliadis N. Transition Met. Chem. 9:1984;77.
25. G.M. Sheldrick, SHELXS-86: Structure Solving Program, University of Göttingen, Germany, 1986.
26. G.M. Sheldrick, SHELXL-93: Crystal Structure Refinement, University of Göttingen, Germany, 1993.
27. International Tables for X-ray Crystallography, vol. IV, Kynoch Press, Birmingham, UK, 1974.
28. C.K. Johnson, ORTEPII. Report ORNL-5138, Oak Ridge National Laboratory, TN, USA, 1976.
29. A.L. Spek, PLATON. A Program for the Automated Generation of a Variety of Geometrical Entities, University of Utrecht, Netherlands, 1997.
30. L.J. Bellamy, The Infrared Spectra of Complex Molecules, Chapman and Hall, London, 1978.
31. Drago R.S., Kovala-Demertzi D., Ferris D.C. J. Coord. Chem. 32:1994;145.
32. A.B.P. Lever, Inorganic Electronic Speectroscopy, Elsevier, New York, 1984.
33. Kovala-Demertzi D., Tsangaris J.M., Desseyn H.O., Van der Veken B.J. Bull. Soc. Chim. Belg. 1:1987;7.
34. West D.W., Saleda J.S., Liberta A.E. Transition Met. Chem. 17:1991;568.
35. Kovala-Demertzi D., Varagi V., Demertzis M.A., Raptopoulou C.P., Terzis A. Acta Crystallogr., Sect. C. 52:1996;2027.
36. Domopoulou A., Michaelidis A., Skoulika S., Kovala-Demertzi D. J. Cryst. Growth. 191:1998;166.
37. Jeffrey G.A., Maluszynska H., Mitra J. Int. J. Biol. Macromol. 7:1985;336.
38. Bordwell F.G., Ji G.Z. J. Am. Chem. Soc. 113:1991;8398.
39. Steiner Th. Cryst. Rev. 6:1996;1.
40. R. Cini, J. Chem. Soc., Dalton Trans. (1996) 111.
41. Goldberg K.I., Valdes-Martinez J., Espinoza-Perez G., Ackerman L.J., West D.X. Polyhedron. 18:1999;1177.
42. Beherens B.C., Hamilton T.C., Msuda H., Grotzinger K.R., Whang-Peng J., Louie K.G., Knutsen T., McKoy W.M., Young R.C., Ozols R.F. Cancer Res. 47:1987;414.
43. Coluccia M., Nassi A., Boccarelli A., Giordano D., Locker D., Leng M., Sivo M., Intini F.P., Natile G. J. Inorg. Biochem. 77:1999;31.