In vitro and in vivo antitumour activity and cellular pharmacological properties of new platinum-iminoether complexes with different configuration at the iminoether ligands

Journal of Inorganic Biochemistry

Volumn 77, Issue 1-2, 1999, Pages 31-35

  Coluccia, Mauro ^a   Nassi, Anna ^a   Boccarelli, Angela ^a   Giordano, Domenico ^a   Cardellicchio, Nicola ^b   Locker, Daniel ^c   Leng, Marc ^c   Sivo, Maria ^d   Intini, Francesco P ^d   Natile, Giovanni ^d  

^a UNIVERSITY OF BARI   (Italy)

^b CNR   (Italy)

^c CENTRE DE BIOPHYSIQUE MOLÉCULAIRE   (France)

^d Dipartimento Farmaco Chimico   (Italy)

Author keywords

Anticancer agents; Cellular accumulation; Excision repair defective Drosophila; trans Platinum iminoether

Indexed keywords

CISPLATIN DERIVATIVE; CISPLATIN IMINOETHER COMPLEX; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; COMPLEX FORMATION; DROSOPHILA; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG STRUCTURE; HUMAN; HUMAN CELL; LIGAND BINDING; METAL BINDING; OVARY CANCER;

ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA; CELL DIVISION; CISPLATIN; DNA REPAIR; DNA, NEOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; DROSOPHILA; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; IMINES; LEUKEMIA P388; MICE; MICE, INBRED STRAINS; ORGANOPLATINUM COMPOUNDS; OVARIAN NEOPLASMS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0033367354     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0162-0134(99)00139-7     Document Type: Article

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