Effect of ring fluorination on the pharmacology of hallucinogenic tryptamines

Journal of Medicinal Chemistry

Volumn 43, Issue 24, 2000, Pages 4701-4710

  Blair, J B ^a   Kurrasch Orbaugh, D ^a   Marona Lewicka, D ^a   Gumbay, M G ^a   Watts, V J ^a   Barker, E L ^a   Nichols, D E ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 4 FLUORO 5 METHOXYDIMETHYLTRYPTAMINE; 5 METHOXY N,N DIMETHYLTRYPTAMINE; LY 293284; LY 293294; N,N DIETHYLTRYPTAMINE; PSILOCIN; PSYCHEDELIC AGENT; SEROTONIN 1A AGONIST; SEROTONIN 1A RECEPTOR; SEROTONIN 2A AGONIST; SEROTONIN 2A RECEPTOR; SEROTONIN 2C RECEPTOR; TRYPTAMINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING COMPETITION; CHEMICAL MODIFICATION; DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; FLUORINATION; MALE; NONHUMAN; RAT;

3T3 CELLS; ANIMALS; BINDING, COMPETITIVE; CHO CELLS; CRICETINAE; CYCLIC AMP; DISCRIMINATION LEARNING; DRUG EVALUATION, PRECLINICAL; FLUORINE; FORSKOLIN; HALLUCINOGENS; HUMANS; HYDROLYSIS; MICE; PHOSPHATIDYLINOSITOLS; RADIOLIGAND ASSAY; RATS; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTOR, SEROTONIN, 5-HT2C; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN AGONISTS; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPTAMINES;

EID: 0034736037     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm000339w     Document Type: Article

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