Synthesis and cytokine modulation properties of pyrrolo[2,3.d]-4- pyrimidone nucleosides

Journal of Medicinal Chemistry

Volumn 43, Issue 13, 2000, Pages 2566-2574

  Wang, Guangyi ^a   Tam, Robert C ^a   Gunic, Esmir ^a   Du, Jinfa ^a   Bard, Josie ^a   Pai, Bharati ^a  

^a Valeant Pharmaceuticals International   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 (BETA D RIBOFURANOSYL)PYRROLO[2,3 D] 4 PYRIMIDONE 5 CARBOXAMIDINE; GAMMA INTERFERON; IMMUNOSTIMULATING AGENT; INTERLEUKIN 4; INTERLEUKIN 5; NUCLEOSIDE DERIVATIVE; PYRIMIDINONE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CHEMICAL REACTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOSTIMULATION; REACTION ANALYSIS; T LYMPHOCYTE;

ADJUVANTS, IMMUNOLOGIC; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; NUCLEOSIDES; PYRIMIDINE NUCLEOSIDES; PYRIMIDINONES; STRUCTURE-ACTIVITY RELATIONSHIP; T-LYMPHOCYTES;

EID: 0034729743     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm000035+     Document Type: Article

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