Synthesis of 5,6-dihydro-4-hydroxy-2-pyrones via formal cycloaddition reactions

Tetrahedron Letters

Volumn 41, Issue 18, 2000, Pages 3299-3302

  Liu, Kun ^a   Xu, Libo ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5,6 DIHYDRO 4 HYDROXY 2 PYRONE DERIVATIVE; ALDEHYDE DERIVATIVE; PYRAN DERIVATIVE; PYRANDIONE; PYRONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CYCLIZATION; DRUG STRUCTURE; PARTIAL DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0034728929     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)00422-6     Document Type: Article

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13. 6) δ 9.27 (d, J=5.3 Hz, 1H), 8.34 (d, J=8.4 Hz, 1H), 8.29 (d, J=8.5 Hz, 1H), 8.08 (t, J=8.4 Hz, 1H), 8.02 (d, J=5.0 Hz, 1H), 7.96 (t, J=8.4 Hz, 1H), 7.20 (m, 5H), 6.07 (s, 1H), 5.36 (s, 1H).
14. 6) δ 8.74 (d, J=2.4 Hz, 1H), 8.51 (dd, J=2.4, 8.5 Hz, 1H), 7.99 (d, J=8.6 Hz, 1H), 7.89 (d, J=7.2 Hz, 2H), 7.32 (t, J=7.5 Hz, 2H), 7.20 (m, 1H), 5.31 (dd, J=3.8, 7.9 Hz, 1H), 4.06 (dd, J=3.8, 14.4 Hz, 1H), 3.56 (dd, J=7.9, 14.5 Hz, 1H).