Quantitative analysis of Helicobacter pylori infection in a mouse model

Journal of Immunological Methods

Volumn 242, Issue 1-2, 2000, Pages 67-78

  Smythies, Lesley E ^a   Chen, Jo Anne ^a   Lindsey, J Russell ^b   Ghiara, Paolo ^e   Smith, Phillip D ^d   Waites, Ken B ^c  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE   (United States)

^c University of Alabama at Birmingham   (United States)

^d BIRMINGHAM VA MEDICAL CENTER   (United States)

^e CHIRON VACCINES   (Italy)

Author keywords

Helicobacter pylori; Immunology; Mouse model; Mucosa; T helper

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL COLONIZATION; BACTERIUM ISOLATE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC PROCEDURE; GRAM NEGATIVE INFECTION; HELICOBACTER PYLORI; INFECTION SENSITIVITY; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PERSISTENT INFECTION; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMAL; ANTIBODIES, BACTERIAL; DISEASE MODELS, ANIMAL; DISEASE SUSCEPTIBILITY; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMAN; IMMUNOGLOBULIN G; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0034726414     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(00)00215-5     Document Type: Article

References (37)

1. Andersen A.P., Elliott D.A., Lawson M., Barland P., Hatcher V.B., Puszkin E.G. Growth and morphological transformations of Helicobacter pylori in broth media. J. Clin. Microbiol. 35:1997;2918.
2. Atherton J.C., Cao P., Peek J.R.M., Tummuru M.K.R., Blaser M.J., Cover T.L. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. J. Biol. Chem. 270:1995;17771.
3. Blaser M.J., Perez-Perez G.I., Kleanthous H., Cover T.L., Peek R.M., Chyou P.H., Stemmermann G.N., Nomura A. Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res. 55:1995;2111.
4. Bode G., Mauch F., Malfertheiner P. The coccoid forms of Helicobacter pylori. Criteria for their viability. Epidemiol. Infect. 111:1993;483.
5. Drazek E.S., Dubois A., Holmes R.K. Characterization and presumptive identification of Helicobacter pylori isolates from rhesus monkeys. J. Clin. Microbiol. 32:1994;1799.
6. Dubois A., Berg D.E., Incecik E.T., Fiala N., Heman-Ackah L.M., Perez-Perez G.I., Blaser M.J. Transient and persistent experimental infection of nonhuman primates with Helicobacter pylori: implications for human disease. Infect. Immun. 64:1996;2885.
7. Eaton K.A., Catrenich C.E., Makin K.M., Krakowka S. Virulence of coccoid and bacillary forms of Helicobacter pylori in gnotobiotic piglets. J. Infect. Dis. 171:1995;459.
8. Ermak T.H., Giannasca P.J., Nichols R., Myers G.A., Nedrud J., Wiltzin R., Lee C.K., Kleanthous H., Monath T.P. Immunization of mice with urease vaccine affords protection against Helicobacter pylori infection in the absence of antibodies and is mediated by MHC Class II-restricted responses. J. Exp. Med. 188:1998;1.
9. Engstrand L., Nguyen A.M., Graham D.Y., el-Saatari F.A. Reverse transcription and polymerase chain reaction amplification of rRNA for detection of Helicobacter species. J. Clin. Microbiol. 30:1992;2295.
10. Faulkner C.B., Simecka J.W., Davidson M.K., Davis J.K., Schoeb T.R., Lindsey J.R., Everson M.P. Gene expression and production of tumor necrosis factor-α, interleukin 1, interleukin 6, and gamma interferon in C3H/HeN and C57BL/6N mice in acute mycoplasma pulmonis disease. Infect. Immun. 63:1995;4084.
11. Ferrero R.L., Thiberge J.M., Huerre M., Labigne A. Recombinant antigens prepared from the urease subunits of Helicobacter spp.: evidence of protection in a mouse model of gastric infection. Infect. Immun. 62:1994;4981.
12. Ferrero R.L., Thiberge J.M., Huerre M., Labigne A. Immune responses of specific-pathogen-free mice to chronic Helicobacter pylori (strain SS1) infection. Infect. Immun. 66:1998;1349.
13. Figura, N.P., Guglielmetti, A., Rossolini, A., Barberi, G., Cusi, R.A., Musmanno, M., Rusi, Quaranta, S., 1989. Cytotoxin production by Campylobacter pylori strains isolated from patients with peptic ulcers and from patients with chronic gastritis only. J. Clin. Microbiol. 27, 225.
14. Fox J.G., Perkins S., Yan L., Shen Z., Attardo L., Pappo J. Local immune response in Helicobacter pylori-infected cats and identification of H. pylori in saliva, gastric fluid and faeces. Immunology. 88:1996;400.
15. Ghiara P., Rossi M., Marchetti M., Di Tommaso A., Vindigni C., Diampolini F., Covacci A., Teleford J.L., De Magistris M.T., Pizza M., Rappuoli R., Del Giudice G. Therapeutic intragastric vaccination against Helicobacter pylori in mice eradicates an otherwise chronic infection and confers protection against reinfection. Infect. Immun. 65:1997;4996.
16. Goto T., Nishizono A., Fujioka T., Ikewaki J., Mifune K., Nasu M. Local secretory immunoglobulin A and postimmunization gastritis correlate with protection against Helicobacter pylori infection after oral vaccination of mice. Infect. Immun. 67:1999;2531.
17. Hansson L.-E., Nyren O.A.W.H., Bergstrom R., Josefsson S., Chow W.-H., Fraumeni J.F., Adami H.-O. The risk of stomach cancer in patients with gastric or duodenal ulcer disease. New Engl. J. Med. 335:1996;242.
18. Harris P.R., Mobley H.L., Perez-Perez G.I., Blaser M.J., Smith P.D. Helicobacter pylori urease is a potent stimulus of mononuclear phagocyte activation and inflammatory cytokine production. Gastroenterology. 111:1996;419.
19. b H chain constant regions are derived from two distinct isotypic genes. Immunogenetics. 29:1989;92.
20. Karita M., Kouchiyama T., Okita K., Nakazawa T. New small animal model for human gastric Helicobacter pylori infection: success in both nude and euthymic mice. Am. J. Gastroenterol. 86:1991;1596.
21. Karita M., Li Q., Cantero D., Okita K. Establishment of a small animal model for human Helicobacter pylori infection using germ-free mouse. Am. J. Gastroenterol. 89:1994;208.
22. Kleanthous, H.G.A., Myers, K.M., Georgakopoulos, T.J., Tibbitts, J.I., Ingrassia, H.L., Gray, R., Ding, Z., Zhang, W., Lei, R., Nichols, C.K., Lee, T.H., Ermak, Monath, T.P., 1998. Rectal and intranasal immunizations with recombinant urease induce distinct local and serum immune responses in mice and protect against Helicobater pylori infection. Infect. Immun. 66, 2879.
23. Krakowka S., Morgan D.R., Kraft W.G., Leunk R.D. Establishment of gastric Campylobacter pylori infection in the neonatal gnotobiotic piglet. Infect. Immun. 55:1987;2789.
24. Marchetti M., Arico B., Burroni D., Figura N., Rappuoli R., Ghiara P. Development of a mouse model of Helicobacter pylori infection that mimics human disease. Science. 267:1995;1655.
25. Martin R.M., Lew A.M. Is IgG2a a good Th1 marker in mice? Immunol. Today. 19:1998.
26. Martin R.M., Silva A., Lew A.M. The Igh-1 sequence of the non-obese diabetic (NOD) mouse assigns it to the IgG2c isotype. Immunogenetics. 46:1997;167.
27. Mohammadi M., Czinn S., Redline R., Nedrud J. Helicobacter-specific cell-mediated immune responses display a predominant Th1 phenotye and promote a delayed-type hypersensitivity response in the stomachs of mice. J. Immunol. 156:1996;4729.
28. Mohammadi M., Nedrud J., Redline R., Lycke N., Czinn S. Murine CD4 t-cell response to Helicobacter infection: Th1 cells enhance gastritist and Th2 cells reduce bacterial load. Gastroenterology. 113:1997;1848.
29. Novak M.J., Smythies L.E., McPherson S.A., Smith P.D., Morrow C.D. Poliovirus replicons encoding the B subunit of Helicobacter pylori urease elicit a Th1 associated immune response. Vaccine. 17:1999;2384.
30. Parsonnet J., Hansen S., Rodriguez L., Gelb A.B., Warnke R.A., Jellum E., Orentreich N., Vogelman J.H., Friedman G.D. Helicobacter pylori infection and gastric lymphoma. New Engl. J. Med. 330:1994;1267.
31. Sakagami T., Dixon M., O'Rourke J., Howlett R., Alderuccio F., Vella J.S.T., Lee A. Atrophic gastric changes in both Helicobacter felis and Helicobacter pylori infected mice are host dependent and separate from antral gastritis. Gut. 39:1996;639.
32. Smythies L.E., Waites K.B., Lindsey J.R., Harris P.R., Ghiara P., Smith P.D. Helicobacter pylori-induced mucosal inflammation is Th1 mediated and exacerbated in IL-4, but not IFN-γ, gene-deficient mice. J. Immunol. 165:2000;1022.
33. Snapper C.M., Paul W.E. Interferon-g and B cell stimulatory factor-1 reciprocally regulate Ig isotype production. Science. 236:1987;944.
34. Telford J.L., Ghjiara M., Dell'Oreo M., Comanducci D., Burroni M., Bugnoli M.F., Tecce S.C.A., Covacci Z., Xiang Z. Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease. J. Exp. Med. 179:1994;1653.
35. Tummuru M.K., Cover T.L., Blaser M.J. Cloning and expression of a high-molecular mass major antigen of Helicobacter pylori: evidence of linkage to cytotoxin production. Infect. Immun. 61:1993;1799.
36. Watanabe T., Tada M., Nagai H., Sasaki S., Nakao M. Helicobacter pylori infection induces gastric cancer in Mongolian gerbils. Gastroenterology. 115:1998;642.
37. Xia H.X., Keane C.T., O'Morain C.A. Pre-formed urease activity of Helicobacter pylori as determined by a viable cell count technique - clinical implications. J. Med. Microbiol. 40:1994;435.