Cell polarity: Scaffold proteins par excellence

Current Biology

Volumn 10, Issue 16, 2000, Pages

  Brazil, Derek P ^a   Hemmings, Brian A ^a  

^a FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0034710617     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(00)00635-7     Document Type: Review

References (10)

1. Polarized signaling:basolateral receptor localization in epithelial cells by PDZ-containing proteins
2. Neuronal polarity and the epithelial metaphor
3. The cell polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42
4. The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is an effector for the Rho GTPase Cdc42
5. A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signaling and cell polarity
6. A human homolog of the C. elegans polarity determinant Par-6 links Rac and Cdc42 to PKCζ signaling and cell transformation
7. The Drosophila homolog of C. elegans PAR-1 organizes the oocyte cytoskeleton and directs oskar mRNA localization to the posterior pole
8. Atypical protein kinases Cλ and -ζ associate with the GTP-binding protein Cdc42 and mediate stress fibre loss
9. The γ-subunit of the coatomer complex binds Cdc42 to mediate transformation
10. Cell polarity: Par for the polar course