Unaltered endothelium-dependent modulation of contraction in the pulmonary artery of hypertensive rats

European Journal of Pharmacology

Volumn 392, Issue 1-2, 2000, Pages 61-70

  Matsuda, Kyoko ^a   Sekiguchi, Fumiko ^a   Yamamoto, Kazuo ^a   Shimamura, Keiichi ^a   Sunano, Satoru ^a  

^a KINKI UNIVERSITY   (Japan)

Author keywords

Adrenoceptors; Endothelium; Nitric oxide (NO); Pulmonary artery; Stroke prone spontaneously hypertensive rats (SHRSP)

Indexed keywords

ACETYLCHOLINE; ALPHA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; ALPHA ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; ARGININE; AZEPEXOLE; BRIMONIDINE; METHOXAMINE; N(G) NITROARGININE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; NORADRENALIN; PAPAVERINE; PHENYLEPHRINE; PROPRANOLOL; VERAPAMIL;

ANIMAL MODEL; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTERY ENDOTHELIUM; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENTIATION; HEREDITARY HYPERTENSION; ISOLATED ARTERY; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; RAT; SMOOTH MUSCLE CONTRACTILITY; SPONTANEOUSLY HYPERTENSIVE RAT;

ADRENERGIC ALPHA-AGONISTS; ANIMALS; BLOOD PRESSURE; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; HYPERTENSION; METHOXAMINE; NITRIC OXIDE; NITROARGININE; NOREPINEPHRINE; PHENYLEPHRINE; PULMONARY ARTERY; RATS; RATS, INBRED SHR; RATS, INBRED WKY; VASOCONSTRICTION;

EID: 0034708467     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00073-X     Document Type: Article

References (44)

1. Adeagbo A.S.O., Triggle C.R. Interactions of nitric oxide synthase inhibitors and dexamethasone with α-adrenoceptor-mediated responses in rat aorta. Br. J. Pharmacol. 109:1993;495-501.
2. Aharinejad S., Schraufnagel D.E., Böck P., MacKay C.A., Larson E.K., Miksovsky A., Marks S.C. Jr. Spontaneously hypertensive rats develop pulmonary hypertension and hypertrophy of pulmonary venous sphincters. Am. J. Pathol. 148:1996;281-290.
3. Alosachie I., Godfraind T. The modulatory role of vascular endothelium in the interaction of agonists and antagonists with α-adrenoceptors in the rat aorta. Br. J. Pharmacol. 95:1988;619-629.
4. 2-Adrenoceptors and endothelium-dependent relaxation in canine large arteries. Br. J. Pharmacol. 88:1986;767-777.
5. Carrier G.O., White R.E. Enhancement of alpha-1 and alpha-2 adrenergic agonist-induced vasoconstriction by removal of endothelium in rat aorta. J. Pharmacol. Exp. Ther. 232:1985;682-687.
6. Clozel M., Kuhn H., Hefti F. Effects of angiotensin converting enzyme inhibitors and of hydralazine on endothelial function in hypertensive rats. Hypertension. 16:1990;532-540.
7. Cocks T.M., Angus J.A. Endothelium-dependent relaxation of coronary arteries by noradrenaline and serotonin. Nature. 305:1983;627-630.
8. Cohen R.A., Vanhoutte P.M. Endothelium-dependent hyperpolarization beyond nitric oxide and cyclic GMP. Circulation. 92:1995;3337-3349.
9. Diederich D., Yang Z., Bühler F.R., Lüscher T.F. Impaired endothelium-dependent relaxations in hypertensive resistance arteries involve cyclooxygenase pathway. Am. J. Physiol. 258:1990;H445-H451.
10. Dohi Y., Criscione L., Pfeiffer K., Lüscher T.F. Angiotensin blockade or calcium antagonists improve endothelial dysfunction in hypertension: studies in perfused mesenteric resistance arteries. J. Cardiovasc. Pharmacol. 24:1994;372-379.
11. Egléme C., Godfraind T., Miller R.C. Enhanced responsiveness of rat isolated aorta to clonidine after removal of the endothelial cells. Br. J. Pharmacol. 81:1984;16-18.
12. Flower R.J. Drugs which inhibit prostaglandin biosynthesis. Pharmacol. Rev. 26:1974;33-67.
13. Furchgott R.F. The role of endothelium in the responses of vascular smooth muscle to drugs. Annu. Rev. Pharmacol. Toxicol. 24:1984;175-197.
14. ω-nitro-L-arginine: a potent inhibitor of endothelium-derived relaxing factor formation. Eur. J. Pharmacol. 176:1990;219-223.
15. Ito S., Carretero O.A. Impaired response to acetylcholine despite intact endothelium-derived relaxing factor/nitric oxide in isolated microperfused afferent arterioles of the spontaneously hypertensive rat. J. Cardiovasc. Pharmacol. 20(Suppl. 12):1992;S187-S189.
16. Kaneko K., Sunano S. Involvement of α-adrenoceptors in the endothelium-dependent depression of noradrenaline-induced contraction in rat aorta. Eur. J. Pharmacol. 240:1993;195-200.
17. Lüscher T.F., Diederich D., Weber E., Vanhoutte P.M., Bühler F.R. Endothelium-dependent responses in carotid and renal arteries of normotensive and hypertensive rats. Hypertension. 11:1988;573-578.
18. Lüscher T.F., Vanhoutte P.M. Endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat. Hypertension. 8:1986;344-348.
19. Lüscher T.F., Vanhoutte P.M. Hypertension and endothelium-dependent responses. Vanhoutte P.M. Vascular Smooth muscle, Peptides, Autonomic Nerves, and Endothelium. 1988;523-529 Raven Press, New York, NY.
20. Marletta M.A. Nitric oxide synthase structure and mechanism. J. Biol. Chem. 268:1993;12231-12234.
21. Martin W., Furchgott R.F., Villani G.M., Jothianandan D. Depression of contractile responses in rat aorta by spontaneously released endothelium-derived relaxing factor. J. Pharmacol. Exp. Ther. 237:1986;529-538.
22. G-nitro-L-arginine on α-agonists-induced contraction of aortae from Wistar Kyoto rats and stroke-prone spontaneously hypertensive rats. J. Smooth Muscle Res. 31:1995;51-60.
23. 2-adrenoceptors in canine pulmonary and systemic blood vessels. Eur. J. Pharmacol. 118:1985;123-129.
24. G-nitro-arginine (L-NOARG), a novel, L-arginine-reversible inhibitor of endothelium-dependent vasodilation in vitro. Br. J. Pharmacol. 99:1990;408-412.
25. Okamoto K., Yamori Y., Nagaoka A. Establishment of the stroke-prone spontaneously hypertensive rat (SHR). Circ. Res. 34-35(Suppl):1974;143-153.
26. Palmer R.M.J., Rees D.D., Ashton D.S., Moncada S. L-Arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation. Biochem. Biophys. Res. Commun. 153:1988;1251-1256.
27. Priest R.M., Hucks D., Ward J.P.T. Noradrenaline, β-adrenoceptor mediated vasorelaxation and nitric oxide in large and small pulmonary arteries of the rat. Br. J. Pharmacol. 122:1997;1375-1384.
28. Rapoport R.M., Murad F. Agonist-induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cGMP. Circ. Res. 52:1983;352-357.
29. Rees D.D., Palmer R.M.J., Schulz P.R., Hodson H.F., Moncada S. Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br. J. Pharmacol. 101:1990;746-752.
30. Sawada Y., Sakamaki T., Nakamura T., Sato K., Ono Z., Murata K. Release of nitric oxide in response to acetylcholine is unaltered in spontaneously hypertensive rats. J. Hypertens. 12:1994;745-750.
31. Shimamura K., Osugi S., Moriyama K., Sunano S. Impairment and protection of endothelium-dependent relaxation in aortae of various strains of spontaneously hypertensive rats. J. Cardiovasc. Pharmacol. 17(Suppl. 3):1991;S133-S136.
32. Takase H., Moreau P., Küng C.F., Nava E., Lüscher T.F. Antihypertensive therapy prevents endothelial dysfunction in chronic nitric oxide deficiency. Hypertension. 27:1996;25-31.
33. Sunano S., Osugi S., Kaneko K., Yamamoto K., Shimamura K. Effects of chronic treatment with SQ29852 on spontaneous smooth muscle tone and endothelium-dependent relaxation in aorta of stroke-prone spontaneously hypertensive rats. J. Cardiovasc. Pharmacol. 19:1992;602-609.
34. Sunano S., Osugi S., Shimamura K. Blood pressure and impairment of endothelium-dependent relaxation in spontaneously hypertensive rats. Experientia. 45:1989;705-708.
35. 2-adrenoceptor agonists in spontaneously hypertensive rat aorta. J. Cardiovasc. Pharmacol. 27:1996;733-739.
36. 3H-adrenaline. Nature. 270:1977;261.
37. Vanhoutte P.M. Endothelium and control of vascular function state of the art lecture. Hypertension. 13:1989;658-667.
38. Vanhoutte P.M., Boulanger C.M. Endothelium-dependent responses in hypertension. Hypertens. Res. 18:1995;87-98.
39. Vanhoutte P.M., Rubanyi G.M., Miller V.M., Houston D.S. Modulation of vascular smooth muscle contraction by the endothelium. Annu. Rev. Physiol. 48:1986;307-320.
40. Vinet R., Brieva C., Pinardi G., Penna M. Modulation of α-adrenergic-induced contractions by endothelium-derived relaxing factor in rat aorta. Gen. Pharmacol. 22:1991;137-142.
41. Vo P.A., Reid J.J., Rand M.J. Attenuation of vasoconstriction by endogenous nitric oxide in rat caudal artery. Br. J. Pharmacol. 107:1992;1121-1128.
42. Watt P.A.C., Thurston H. Endothelium-dependent relaxation in resistance vessels from the spontaneously hypertensive rats. J. Hypertens. 7:1989;661-666.
43. 2-adrenoceptor agonist-induced contraction in rat mesenteric artery upon removal of endothelium. Eur. J. Pharmacol. 122:1986;349-352.
44. Yaghi A., Paterson N.A.M., McCormack D.G. Differential effect of nitric oxide synthase inhibitors on acetylcholine-induced relaxation of rat pulmonary and celiac artery rings. Can. J. Physiol. Pharmacol. 75:1997;279-286.