The indolocarbazole Go6976 protects neurons from lipopolysaccharide/interferon-γ-induced cytotoxicity in murine neuron/glia co-cultures

Molecular Brain Research

Volumn 79, Issue 1-2, 2000, Pages 32-44

  Jeohn, G H ^a   Wilson, B ^a   Wetsel, W C ^b   Hong, J S ^a  

^a Neuropharmacology Section   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Endotoxin; Glia; Lipopolysaccharide; Neuroprotection; Neurotoxicity; Protein kinase C

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; 2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; GAMMA INTERFERON; GOE 7874; INTERLEUKIN 1ALPHA; LIPOPOLYSACCHARIDE; MESSENGER RNA; N (2 METHYLAMINOETHYL) 5 ISOQUINOLINESULFONAMIDE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHORBOL ESTER; PROTEIN KINASE C INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CARBAZOLE DERIVATIVE; INDOLE DERIVATIVE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1; MICROTUBULE ASSOCIATED PROTEIN; NERVE CELL ADHESION MOLECULE; NEUROPROTECTIVE AGENT; NOS2 PROTEIN, MOUSE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; RECOMBINANT GAMMA INTERFERON; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DEATH; COCULTURE; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; ENZYME ACTIVITY; GENE EXPRESSION; GLIA CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; MOUSE; NERVE CELL; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; CELL SURVIVAL; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; GLIA; NEWBORN; PHYSIOLOGY;

ANIMALS; ANIMALS, NEWBORN; CARBAZOLES; CELL SURVIVAL; COCULTURE TECHNIQUES; GENE EXPRESSION REGULATION; INDOLES; INTERFERON-GAMMA, RECOMBINANT; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; MICE; MICROTUBULE-ASSOCIATED PROTEINS; NEURAL CELL ADHESION MOLECULES; NEUROGLIA; NEURONS; NEUROPROTECTIVE AGENTS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PROTEIN KINASE C; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TETRADECANOYLPHORBOL ACETATE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034705572     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(00)00082-6     Document Type: Article

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