Comparison of [3H]tamsulosin and [3H]prazosin binding to wild-type and constitutively active α1(B)-adrenoceptors

Life Sciences

Volumn 67, Issue 5, 2000, Pages 503-508

  Hein, Peter ^a   Goepel, Mark ^a   Cotecchia, Susanna ^b   Michel, Martin C ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

1(B) Adrenoceptor; 3H Prazosin; 3H Tamsulosin; Constitutively active receptor; Radioligand binding

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; PRAZOSIN; TAMSULOSIN; ADRENERGIC RECEPTOR ALPHA(1B); ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; SULFONAMIDE; TRITIUM;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; DRUG RECEPTOR BINDING; HAMSTER; LIGAND BINDING; MALE; NONHUMAN; RAT; ANIMAL; COMPARATIVE STUDY; METABOLISM; RADIOASSAY; WISTAR RAT;

ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; CRICETINAE; MALE; PRAZOSIN; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA-1; SULFONAMIDES; TRITIUM;

EID: 0034705234     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(00)00652-4     Document Type: Article

References (13)

1. H. Yazawa, M. Takanashi, K. Sudoh, O. Inagaki, and K. Honda, J. Pharmacol. Exp. Ther. 263 201-206 (1992).
2. M.C. Michel and M. Goepel, Eur. J. Pharmacol. 342 85-92 (1998).
3. M.C. Michel, B.A. Kenny, and D.A. Schwinn, Naunyn-Schmiedeberg's Arch. Pharmacol. 352 1-10 (1995).
4. M.A. Kjelsberg, S. Cotecchia, J. Ostrowski, M.G. Caron, and R.J. Lefkowitz, J. Biol. Chem. 267 1430-1433 (1992).
5. T.W. Lee, A. Wise, S. Cotecchia, and G. Milligan, Biochem. J. 320 79-86 (1996).
6. L.F. Allen, R.J. Lefkowitz, M.G. Caron, and S. Cotecchia, Proc. Natl. Acad. Sci. USA 88 11354-11358 (1991).
7. D. Langin, M. Lafontan, M.R. Stilings, and H. Paris, Eur. J. Pharmacol. 167 95-104 (1989).
8. J. Galitzky, J.M. Senard, M. Lafontan, M. Stillings, J.L. Montastruc, and M. Berlan, Br. J. Pharmacol. 100 862-866 (1990).
9. A.C. Mackinnon, A.T. Kilpatrick, B.A. Kenny, M. Spedding, and C.M. Brown, Br. J. PharmaCol. 106 1011-1018 (1992).
10. W. Erdbrügger, M. Raulf, T. Otto, and M.C. Michel, J. Pharmacol. Exp. Ther. 273 1287-1294 (1995).
11. B. Djavan and M. Marberger, Eur. Urol. 36 1-13 (1999).
12. M.C. Michel, B. Grübbel, K. Taguchi, F. Verfürth, T. Otto, and D. Kröpfl, J. Auton. Pharmacol. 16 21-28 (1996).
13. T.W. Lee, S. Cotecchia, and G. Milligan, Biochem. J. 325 733-739 (1997).