The three-dimensional high resolution structure of human interferon α-2a determined by heteronuclear NMR spectroscopy in solution

Journal of Molecular Biology

Volumn 274, Issue 4, 1997, Pages 661-675

  Klaus, Werner ^a   Gsell, Bernard ^a   Labhardt, Alexander M ^a   Wipf, Beat ^a   Senn, Hans ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Cytokine; Four helix bundle; Interferon ; NMR spectroscopy; Protein structure

Indexed keywords

ALPHA2A INTERFERON; ALPHA2B INTERFERON; BETA INTERFERON; CYTOKINE; DISULFIDE; METHYL GROUP; NITROGEN 15; RECOMBINANT ALPHA2A INTERFERON;

ALPHA HELIX; AMINO ACID SEQUENCE; AQUEOUS SOLUTION; ARTICLE; DRUG STRUCTURE; HUMAN; HYDROGEN BOND; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN TERTIARY STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOSPECIFICITY;

MURINAE; STAPHYLOCOCCUS PHAGE 187;

EID: 0031566032     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1997.1396     Document Type: Article

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